Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Anthony, Meager"'
Autor:
Anette S.B. Wolff, Lena Hansen, Marianne Aa. Grytaas, Bergithe E. Oftedal, Lars Breivik, Fan Zhou, Karl Ove Hufthammer, Thea Sjøgren, Jan Stefan Olofsson, Mai Chi Trieu, Anthony Meager, Anders P. Jørgensen, Kari Lima, Kristin Greve-Isdahl Mohn, Nina Langeland, Rebecca Jane Cox, Eystein S. Husebye
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107084- (2023)
Summary: A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of these antibodies has been associated with severe course of COVID-19.
Externí odkaz:
https://doaj.org/article/14962cf4208b4d55aa645d0083bbb0de
Autor:
Bergithe E. Oftedal, Nicolas Delaleu, David Dolan, Anthony Meager, Eystein S. Husebye, Anette S. B. Wolff
Publikováno v:
FEBS Letters. 597:1261-1274
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea655ef167ab0369919016df865f58ea
https://doi.org/10.1002/1873-3468.14625
https://doi.org/10.1002/1873-3468.14625
Autor:
Bergithe E. Oftedal, Øyvind Bruserud, Amund H. Berger, Sarah Braun, Nicolas Delaleu, David Dolan, Ellen C. Royrvik, Haydee Artaza, Anthony Meager, Eystein S. Husebye, Anette S.B. Wolff
Purpose: Autoimmune polyendocrine syndrome type I (APS-1) is a devastating autoimmune disease characterised by mutations in the AIRE gene. Because of failure of negative selection, these patients produce autoreactive B and T cells against affected ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0125228ad4c8a83b92bc3fc52f9339b5
https://doi.org/10.21203/rs.3.rs-2049437/v1
https://doi.org/10.21203/rs.3.rs-2049437/v1
Publikováno v:
Science. 373
Break et al . (Research Articles, 15 January 2021, eaay5731) conclude that T cell overproduction of interferon-γ causes chronic mucocutaneous candidiasis (CMC), a typical early feature of autoimmune polyendocrinopathy–candidiasis–ectodermal dyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47dd4d0e8d70b3669602505974d478ef
https://doi.org/10.1126/science.abi6235
https://doi.org/10.1126/science.abi6235
Autor:
Anthony Meager, Kumuthini Visvalingam, Pärt Peterson, Kaidi Möll, Astrid Murumägi, Kai Krohn, Petra Eskelin, Jaakko Perheentupa, Eystein Husebye, Yoshihisa Kadota, Nick Willcox
Publikováno v:
PLoS Medicine, Vol 3, Iss 7, p e289 (2006)
The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting endocrine and other epithelial tissues, al
Externí odkaz:
https://doaj.org/article/9bd180eef4174bcd8d23c4a80bc0c904
Autor:
Meenu Wadhwa, Anthony Meager
Publikováno v:
Expert Review of Clinical Immunology. 10:1029-1047
Cytokines regulate many aspects of cell growth and differentiation and play pivotal roles in the orchestration of immune defence against invading pathogens. Though 'self' proteins, they are potentially immunogenic and can give rise to anti-cytokine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0474472f2e66f21e16eb710da625d6
https://doi.org/10.1586/1744666x.2014.918848
https://doi.org/10.1586/1744666x.2014.918848
Autor:
Anthony Meager, Adrian Bristow, Stella C. Williams, Michelle E. McClements, Christine Ball, Meenu Wadhwa
B-cell activating factor (BAFF) is a type II transmembrane glycoprotein belonging to the tumour necrosis factor ligand superfamily. Active soluble forms of BAFF are generated either by cleavage of the extracellular domain or by recombinant DNA techno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4bf8f739343c29e61b7aee379617c8
https://doi.org/10.1016/j.jim.2008.05.013
https://doi.org/10.1016/j.jim.2008.05.013
Autor:
Leslie Jacobson, I. Matthews, W Zhang, Angela Vincent, Ioannis Roxanis, G. P. Sims, Nick Willcox, Anthony Meager, David Beeson, H Shiono, John A. Todd, Y L Wong, M Bonifati, David I. Stott, J.-L Liu, K Micklem
We have studied responses in thymoma patients to interferon-alpha and to the acetylcholine receptor (AChR) in early-onset myasthenia gravis (EOMG), seeking clues to autoimmunizing mechanisms. Our new evidence implicates a two-step process: (step 1) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7896520aa99c5b375afdebb658a39b41
https://ora.ox.ac.uk/objects/uuid:1cc711f2-d27c-44e9-98d9-a5ee2a68c834
https://ora.ox.ac.uk/objects/uuid:1cc711f2-d27c-44e9-98d9-a5ee2a68c834
Autor:
Antonio Cao, Nick Willcox, Eystein S. Husebye, Antonella Meloni, Anette S. B. Wolff, Maria Furcas, Anthony Meager, Mauro Congia, Maria Cristina Rosatelli, Michela Atzeni
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:1114-1124
Autoimmune polyendocrine syndrome type 1 (APS1) is a childhood-onset monogenic disorder caused by mutations in the autoimmune regulator (AIRE) gene, including the distinctive R139X in Sardinia. Its rarity and great variability in manifestations/onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a28825e52fb61a599639e44ca3aca1c
https://doi.org/10.1210/jc.2011-2461
https://doi.org/10.1210/jc.2011-2461
Autor:
Gavin Giovannoni, Silvia Lonardi, Ute-Christiane Meier, Androulla Elia, J.S. Tzartos, Jaap M. Middeldorp, Michael J. Clemens, Anthony Meager, Paul J. Farrell, M. Cruz-Sadaba, Gulfaraz Khan, E. Sefia, Anna Vossenkämper
Publikováno v:
Neurology, 78(1), 15-23. Lippincott Williams and Wilkins
Tzartos, J S, Khan, G, Vossenkamper, A, Cruz-Sabada, M, Lonardi, S, Sefia, E, Meager, A, Elia, A, Middeldorp, J M, Clemens, M, Farrell, P J, Giovannoni, G & Meier, U C 2012, ' Association of innate immune activation with latent Epstein-Barr virus in active MS lesions ', Neurology, vol. 78, no. 1, pp. 15-23 . https://doi.org/10.1212/WNL.0b013e31823ed057
Tzartos, J S, Khan, G, Vossenkamper, A, Cruz-Sabada, M, Lonardi, S, Sefia, E, Meager, A, Elia, A, Middeldorp, J M, Clemens, M, Farrell, P J, Giovannoni, G & Meier, U C 2012, ' Association of innate immune activation with latent Epstein-Barr virus in active MS lesions ', Neurology, vol. 78, no. 1, pp. 15-23 . https://doi.org/10.1212/WNL.0b013e31823ed057
OBJECTIVE: To determine whether the activation of innate immune responses, which can be elicited by pathogenic and endogenous triggers, is associated with the presence of Epstein-Barr virus (EBV) infection in the multiple sclerosis (MS) brain. METHOD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3aff583120dbcf269fcfdd78743e6e
https://doi.org/10.1212/wnl.0b013e31823ed057
https://doi.org/10.1212/wnl.0b013e31823ed057