Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Anthony, Hickey"'
Autor:
Alexandria Ragsdale, Oscar Ortega-Recalde, Ludovic Dutoit, Anne A. Besson, Jolyn H. Z. Chia, Tania King, Shinichi Nakagawa, Anthony Hickey, Neil J. Gemmell, Timothy Hore, Sheri L. Johnson
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background In a time of rapid environmental change, understanding how the challenges experienced by one generation can influence the fitness of future generations is critically needed. Using tolerance assays and transcriptomic and methylome
Externí odkaz:
https://doaj.org/article/8f7c6f8bdc3d4f3d8e6e8f1c6190b911
Autor:
David Edwards, Anthony Hickey, Richard Batycky, Lester Griel, Michael Lipp, Wes Dehaan, Robert Clarke, David Hava, Jason Perry, Brendan Laurenzi, Aidan K. Curran, Brandon J. Beddingfield, Chad J. Roy, Tom Devlin, Robert Langer
Publikováno v:
QRB Discovery, Vol 1 (2020)
We propose the nasal administration of calcium-enriched physiological salts as a new hygienic intervention with possible therapeutic application as a response to the rapid and tenacious spread of COVID-19. We test the effectiveness of these salts aga
Externí odkaz:
https://doaj.org/article/d4158dc6a80b4f18a73d82060ce26014
Autor:
Daniel Joh, Mathew Morreau, Angela Lee, Sayali Pendharkar, Bruce Stokes, Roger Warren, Anthony Hickey, Anthony J. Phillips, John A Windsor
Publikováno v:
ANZ Journal of Surgery. 93:859-868
Acute Mesenteric Ischaemic (AMI) is a rare condition with significant morbidity and mortality. Many causes of AMI exist, which usually begin with mucosal injury. Onset is insiduous and there is frequent diagnostic delay. Current treatments can only c
Autor:
Taryn Chalmers, Blake Anthony Hickey, Phillip Newton, Chin-Teng Lin, David Sibbritt, Craig S. McLachlan, Roderick Clifton-Bligh, John Morley, Sara Lal
Publikováno v:
Sensors, Vol 22, Iss 1, p 151 (2021)
Stress is an inherent part of the normal human experience. Although, for the most part, this stress response is advantageous, chronic, heightened, or inappropriate stress responses can have deleterious effects on the human body. It has been suggested
Externí odkaz:
https://doaj.org/article/8cf5d5756f3740f38bf2a09f14d50f76
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1309 (2021)
Liposomes, as vehicles alone or in combination with rifampicin (RIF) microparticles (RMs), were evaluated as vehicles to enhance the permeation of RIF into granulomas. RIF liposomes (RLs) were extruded through a 0.1 µm polypropylene membrane. RMs we
Externí odkaz:
https://doaj.org/article/d059686356004cf5b451cd9e9bb0ed57
Autor:
Blake Anthony Hickey, Taryn Chalmers, Phillip Newton, Chin-Teng Lin, David Sibbritt, Craig S. McLachlan, Roderick Clifton-Bligh, John Morley, Sara Lal
Publikováno v:
Sensors, Vol 21, Iss 10, p 3461 (2021)
Recently, there has been an increase in the production of devices to monitor mental health and stress as means for expediting detection, and subsequent management of these conditions. The objective of this review is to identify and critically apprais
Externí odkaz:
https://doaj.org/article/63b856137adb429482b9df56598485b5
Autor:
Per Bäckman, Antonio Cabal, Andy Clark, Carsten Ehrhardt, Ben Forbes, Jayne Hastedt, Anthony Hickey, Guenther Hochhaus, Wenlei Jiang, Stavros Kassinos, Philip J. Kuehl, David Prime, Yoen-Ju Son, Simon P. Teague, Ulrika Tehler, Jennifer Wylie
Publikováno v:
Molecular Pharmaceutics. 19:2040-2047
This work is the second in a series of publications outlining the fundamental principles and proposed design of a biopharmaceutics classifications system for inhaled drugs and drug products (the iBCS). Here, a mechanistic computer-based model has bee
Autor:
Jayne E. Hastedt, Per Bäckman, Andrew R. Clark, William Doub, Anthony Hickey, Guenther Hochhaus, Phil J. Kuehl, Claus-Michael Lehr, Peter Mauser, Jason McConville, Ralph Niven, Masahiro Sakagimi, Jeffry G. Weers
Publikováno v:
AAPS Open, Vol 2, Iss 1, Pp 1-20 (2016)
Abstract The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral immediate release drugs, is utilized by R&D scientists and regulators to streamline product development and regulatory approval timelines. This elegant, scienc
Externí odkaz:
https://doaj.org/article/dc4a2a80e1784e56a752697b1c07da75
Autor:
Karen Santos, Pradeep B. Lukka, Anne Grzegorzewicz, Mary Jackson, Ashit Trivedi, Fernando Pavan, Marlus Chorilli, Miriam Braunstein, Anthony Hickey, Bernd Meibohm, Mercedes Gonzalez-Juarrero
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
There is an urgent need to treat tuberculosis (TB) quickly, effectively and without side effects. Mycobacterium tuberculosis (Mtb), the causative organism of TB, can survive for long periods of time within macrophages and dendritic cells and these in
Externí odkaz:
https://doaj.org/article/474f7a8a8f054cdf9c76928c6f2b5eec
Autor:
Shouryadipta, Ghosh, Giovanni, Guglielmi, Ioannis, Orfanidis, Fabian, Spill, Anthony, Hickey, Eric, Hanssen, Vijay, Rajagopal
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 377(1864)
Diabetic cardiomyopathy is a leading cause of heart failure in diabetes. At the cellular level, diabetic cardiomyopathy leads to altered mitochondrial energy metabolism and cardiomyocyte ultrastructure. We combined electron microscopy (EM) and comput