Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anthonieke Middelman"'
Autor:
Anne Stephanie Mallien, Laura Becker, Natascha Pfeiffer, Federica Terraneo, Melissa Hahn, Anthonieke Middelman, Rupert Palme, Kerstin Camile Creutzberg, Veronica Begni, Marco Andrea Riva, Damiana Leo, Heidrun Potschka, Fabio Fumagalli, Judith R. Homberg, Peter Gass
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
In preclinical psychiatry research, animals are central to modeling and understanding biological mechanisms of behavior and psychiatric disorders. We here present the first multimodal severity assessment of a genetically modified rat strain used in p
Externí odkaz:
https://doaj.org/article/f01fe0dd64c74543a7a97544fd93975b
Autor:
Giulia Sbrini, Sabrina I. Hanswijk, Paola Brivio, Anthonieke Middelman, Michael Bader, Fabio Fumagalli, Natalia Alenina, Judith R. Homberg, Francesca Calabrese
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4941 (2022)
Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in the brain, TPH1 is expressed in peripheral organs. Interestingly, despite its peripheral loc
Externí odkaz:
https://doaj.org/article/0d32b3b54d2345e5964bbdd298267006
Autor:
Calabrese, Giulia Sbrini, Sabrina I. Hanswijk, Paola Brivio, Anthonieke Middelman, Michael Bader, Fabio Fumagalli, Natalia Alenina, Judith R. Homberg, Francesca
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4941
Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in the brain, TPH1 is expressed in peripheral organs. Interestingly, despite its peripheral loc
Autor:
Jonathan R. Reinwald, Natalia Gass, Anne S. Mallien, Alexander Sartorius, Robert Becker, Markus Sack, Claudia Falfan-Melgoza, Christian Clemm von Hohenberg, Damiana Leo, Natascha Pfeiffer, Anthonieke Middelman, Andreas Meyer-Lindenberg, Judith R. Homberg, Wolfgang Weber-Fahr, Peter Gass
Publikováno v:
Molecular Psychiatry, 27, 2329-2339
Molecular Psychiatry, 27, 4, pp. 2329-2339
Molecular Psychiatry, 27, 4, pp. 2329-2339
Silencing of dopamine transporter (DAT), a main controlling factor of dopaminergic signaling, results in biochemical and behavioral features characteristic for neuropsychiatric diseases with presumed hyperdopaminergia including schizophrenia, attenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2407915fd4485b965c58c61b433053
http://hdl.handle.net/2066/251346
http://hdl.handle.net/2066/251346
Autor:
Judith R. Homberg, Lidiane P. Garcia, Anthonieke Middelman, Quirijn de Mast, André J. A. M. van der Ven, Gerard J.M. Martens, Sabrina I. Hanswijk, Lisa Van de Wijer, Rob ter Heine, Sharon M. Kolk, J. Rando, Arnt F. A. Schellekens
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 9, Iss 1, Pp 1-12 (2019)
Translational Psychiatry, 9, 1-12
Translational Psychiatry, 9, pp. 1-12
Translational Psychiatry, Vol 9, Iss 1, Pp 1-12 (2019)
Translational Psychiatry, 9, 1-12
Translational Psychiatry, 9, pp. 1-12
Contains fulltext : 201600.pdf (Publisher’s version ) (Open Access) Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus. Efavirenz is known for its central nervous sys
Autor:
Anthonieke Middelman, Lidiane P. Garcia, Gerard J.M. Martens, Josefine S. Witteveen, Sharon M. Kolk, Josephus A. van Hulten, Judith R. Homberg
Publikováno v:
Molecular Neurobiology, 56, 2, pp. 1405-1420
Molecular Neurobiology, 56, 1405-1420
Molecular Neurobiology, 56, pp. 1405-1420
Molecular Neurobiology
Molecular Neurobiology, 56, 1405-1420
Molecular Neurobiology, 56, pp. 1405-1420
Molecular Neurobiology
Proper development of the medial prefrontal cortex (mPFC), crucial for correct cognitive functioning, requires projections from, among others, the serotonergic (5-HT) and catecholaminergic systems, but it is unclear how these systems influence each o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b61ff9be8d72f2a9a0d85912bbf58b7
https://hdl.handle.net/2066/201900
https://hdl.handle.net/2066/201900
Autor:
Anthonieke Middelman, Frances S. de Man, Judith R. Homberg, Norbert F. Voelkel, Harm Jan Bogaard, Helma de Jong, Yvet Kroeze, Michiel Alexander de Raaf, Anton Vonk-Noordegraaf, Chris L. de Korte
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology, 309(10), L1164-L1173. AMER PHYSIOLOGICAL SOC
American Journal of Physiology : Lung Cellular and Molecular Physiology, 309, 10, pp. L1164-73
de Raaf, M A, Kroeze, Y, Middelman, A, de Man, F S, de Jong, H, Vonk-Noordegraaf, A, de Korte, C, Voelkel, N F, Homberg, J & Bogaard, H J 2015, ' Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model ', American Journal of Physiology. Lung Cellular and Molecular Physiology, vol. 309, no. 10, pp. L1164-L1173 . https://doi.org/10.1152/ajplung.00127.2015
American Journal of Physiology : Lung Cellular and Molecular Physiology, 309, L1164-73
American Journal of Physiology. Lung Cellular and Molecular Physiology, 309(10), L1164-L1173. American Physiological Society
American Journal of Physiology : Lung Cellular and Molecular Physiology, 309, 10, pp. L1164-73
de Raaf, M A, Kroeze, Y, Middelman, A, de Man, F S, de Jong, H, Vonk-Noordegraaf, A, de Korte, C, Voelkel, N F, Homberg, J & Bogaard, H J 2015, ' Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model ', American Journal of Physiology. Lung Cellular and Molecular Physiology, vol. 309, no. 10, pp. L1164-L1173 . https://doi.org/10.1152/ajplung.00127.2015
American Journal of Physiology : Lung Cellular and Molecular Physiology, 309, L1164-73
American Journal of Physiology. Lung Cellular and Molecular Physiology, 309(10), L1164-L1173. American Physiological Society
Item does not contain fulltext Increased serotonin serum levels have been proposed to play a key role in pulmonary arterial hypertension (PAH) by regulating vessel tone and vascular smooth muscle cell proliferation. An intact serotonin system, which
Autor:
Anthonieke Middelman, Judith R. Homberg, Bart Dirven, Marijke Kröhnke, Hans van Bokhoven, Stefan Janssen, Yvet Kroeze, Ramona M. Barte, Huiqing Zhou
Publikováno v:
Neuropharmacology, 109, pp. 96-111
Neuropharmacology, 109, 96-111
Neuropharmacology, 109, 96-111
Contains fulltext : 168042.pdf (Publisher’s version ) (Open Access) While there is strong evidence from rodent and human studies that a reduction in serotonin transporter (5-HTT) function in early-life can increase the risk for several neuropsychia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766e5345b6686609269f6692c631c29b
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/168042
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/168042
Autor:
Josefine S. Witteveen, Josephus A. van Hulten, Judith R. Homberg, Sharon M. Kolk, Anthonieke Middelman, Gerardus Julianus Maria Martens
Publikováno v:
Frontiers in Cellular Neuroscience, 7
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Frontiers in Cellular Neuroscience
Contains fulltext : 126007.pdf (Publisher’s version ) (Open Access) Besides its "classical" neurotransmitter function, serotonin (5-HT) has been found to also act as a neurodevelopmental signal. During development, the 5-HT projection system, besid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c21a2f36f39c4c4b2fb99c3601b08de
http://hdl.handle.net/2066/126007
http://hdl.handle.net/2066/126007
Autor:
Giorgio Racagni, Gianluigi Guidotti, Judith R. Homberg, Marco A. Riva, Francesca Calabrese, Anthonieke Middelman
Publikováno v:
Molecular Neurobiology, 48, 244-56
Molecular Neurobiology, 48, 1, pp. 244-56
Molecular Neurobiology, 48, 1, pp. 244-56
Item does not contain fulltext It is well established that alterations of the serotoninergic system may contribute to the pathophysiology of mood disorders. Accordingly, it has been demonstrated that genetic deletion of the serotonin transporter (SER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a416798912edc5c38fb157a4e88065e7
http://hdl.handle.net/2066/126008
http://hdl.handle.net/2066/126008