Výsledky vyhledávání - "Anthea J. Stanley"

A pilot study to investigate the potential of mass spectrometry profiling in the discovery of novel serum markers in chronic renal disease

Autor: Anthea J. Stanley, Douglas Thompson, Andrew Mooney, Jennifer H. Barrett, Peter Selby, Rosamonde E. Banks, David A. Perkins, Willem Develter, David A Cairns

Publikováno v: PROTEOMICS - Clinical Applications. 5:523-531

Purpose: There has been significant criticism of how technologies such as SELDI have been used in biomarker discovery and how the data have been analysed. We initiated a proof-of-principle pilot study using SELDI with stringent pre-analytic and analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ff4fc809069d809c5af3c25c371676
https://doi.org/10.1002/prca.201100009

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Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma

Autor: Rachel A. Craven, Sheryl Sim, Jon Cartledge, David A Cairns, Anthea J. Stanley, Naveen S. Vasudev, Peter Selby, Douglas Thompson, Roisean E. Ferguson, Rosamonde E. Banks

Publikováno v: British Journal of Cancer

Background: No circulating markers are routinely used for renal cancer. The objective of this pilot study was to investigate whether conditioned media (CM) from renal cancer cell lines contains potential biomarkers that, when measured in clinical flu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1721ae52678561119f54b736dc979cf4
http://europepmc.org/articles/PMC2768081

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Using the protein chip interface with quadrupole time-of-flight mass spectrometry to directly identify peaks in SELDI profiles - initial evaluation using low molecular weight serum peaks

Autor: Jianhe Peng, Peter Selby, David A Cairns, Rosamonde E. Banks, Anthea J. Stanley

Publikováno v: PROTEOMICS. 9:492-498

Mass spectrometric profiling, particularly in the form of SELDI, has been used in many studies, particularly in attempts to generate diagnostic serum profiles. Several studies have generated promising results but one of the limitations is the inabili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71a595b03aa7a1424a18f638bd23f00
https://doi.org/10.1002/pmic.200800424

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Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma

Autor: Adrian L. Harris, William S. Trimble, Eamonn R. Maher, Nick Totty, Sarah Hanrahan, Anthea J. Stanley, Patricia Harnden, Rachel A. Craven, Peter Selby, Rosamonde E. Banks

Publikováno v: PROTEOMICS. 6:3880-3893

The von Hippel Lindau (VHL) tumour suppressor gene, VHL, plays a central role in development of sporadic conventional renal cell carcinomas (RCCs). Studying VHL function may, therefore, increase understanding of the pathogenesis of RCC and identify m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0187b8db0e2440858e5ec4165d48cb18
https://doi.org/10.1002/pmic.200500811

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Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma

Autor: Rosamonde E. Banks, Sarah Hanrahan, James Dods, Nick Totty, Anthea J. Stanley, Richard D. Unwin, Patricia Harnden, Ian Eardley, Rachel A. Craven, Peter Selby

Publikováno v: PROTEOMICS. 6:2853-2864

New markers/targets for renal cell carcinoma (RCC) are needed to enable earlier detection and monitoring of disease and therapeutic targeting. To identify such molecules, normal and RCC-derived primary cell lines have been used as a simplified model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec87b67c77d3e90a4b6abe0d58b4e93f
https://doi.org/10.1002/pmic.200500549

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Genetic and Epigenetic Analysis of von Hippel-Lindau (VHL) Gene Alterations and Relationship with Clinical Variables in Sporadic Renal Cancer

Autor: Peter Selby, Patricia Harnden, Margaret A. Knowles, Rosamonde E. Banks, Dewi Astuti, Eamonn R. Maher, Dena Cohen, P. Tirukonda, Anthea J. Stanley, Nick Hornigold, Claire Taylor, Adrian D. Joyce

Publikováno v: Cancer Research. 66:2000-2011

Genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumor suppressor gene are common in sporadic conventional renal cell carcinoma (cRCC). Further insight into the clinical significance of these changes may lead to increased biological unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fb1641e3092c9997e3e421f5ae4655
https://doi.org/10.1158/0008-5472.can-05-3074

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