Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ante Sven Lundberg"'
Autor:
Giulia Pavani, Wassim El Nemer, Oriana Romano, Chiara Antoniani, Ante Sven Lundberg, Yukio Nakamura, Vasco Meneghini, Sara El Hoss, Fulvio Mavilio, Annarita Miccio, Annalisa Lattanzi, Thomas J. Cradick, Mario Amendola, Marina Cavazzana, Ryo Kurita, Tristan Felix, Matthew H. Porteus, Elisa Magrin, Leslie Weber
Publikováno v:
Blood
Blood, American Society of Hematology, 2018, 131, pp.1960-1973. ⟨10.1182/blood-2017-10-811505⟩
Blood, 2018, 131, pp.1960-1973. ⟨10.1182/blood-2017-10-811505⟩
Blood, American Society of Hematology, 2018, 131, pp.1960-1973. ⟨10.1182/blood-2017-10-811505⟩
Blood, 2018, 131, pp.1960-1973. ⟨10.1182/blood-2017-10-811505⟩
International audience; Naturally occurring, large deletions in the beta-globin locus result in hereditary persistence of fetal hemoglobin, a condition that mitigates the clinical severity of sickle cell disease (SCD) and beta-thalassemia. We designe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b03950f429c7272d83511e6c369566
https://hal.archives-ouvertes.fr/hal-02880783
https://hal.archives-ouvertes.fr/hal-02880783
Autor:
Jun Ho Jang, Miklos Egyed, Martin S. Tallman, Ante Sven Lundberg, Richard Stone, Donna Neuberg, Dominik Selleslag, Harry P. Erba, Robert K. Stuart, Emanuele Mazzola, Lloyd E. Damon, Parameswaran Venugopal, Tamas Masszi, David A. Rizzieri, Mikkael A. Sekeres, Meir Wetzler, Heinz A. Horst, Steven L. Allen, Bayard L. Powell, Arnaud Pigneux, Krzysztof Warzocha, Scott R. Solomon
Publikováno v:
Journal of Clinical Oncology. 33:1252-1257
Purpose Secondary acute myeloid leukemia (sAML), defined as AML arising after a prior myelodysplastic syndrome or after antineoplastic therapy, responds poorly to current therapies. It is often associated with adverse karyotypic abnormalities and ove
Autor:
Ante Sven Lundberg, Rodger Novak
Publikováno v:
The American Journal of Bioethics. 15:38-40
CRISPR-Cas9 is a powerful new technique that allows for precise editing of DNA, the genetic code in all the cells of our body. It is also broadly available and easy to use, which has raised the fea...
Autor:
Daniel R. Budman, John M. Bennett, Jonathan E. Kolitz, Robert L. Capizzi, Ante Sven Lundberg, Steven L. Allen
Publikováno v:
Leukemia Research. 34:487-491
Amonafide-l-malate (amonafide) is a unique DNA intercalator that maintains activity in the presence of MDR mechanisms, a frequent cause of treatment-failure in secondary AML. 43 patients with relapsed/refractory or secondary AML or CML blast crisis w
Autor:
Ante Sven Lundberg, Sara Haven, V. M. Holers, Spero R. Cataland, Trudy Wu, Shangbin Yang, Haifeng Wu
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:1925-1927
Autor:
Chad A. Cowan, Michelle I. Lin, Ying Zhang, Tirtha Chakraborty, Song Chou, Rodger Novak, Ante Sven Lundberg, Andrew Sanginario, Bibhu P. Mishra, Michael A. Pettiglio, Ruibin Liang, Matthias John, Melanie Allen, Thomas J. Cradick, Elizabeth J. Paik, Kaleigh Tomkinson
Publikováno v:
Blood. 128:3623-3623
Fetal hemoglobin (HbF) is abundant in the late stage fetus and newborns, but is progressively lost over the first 6 months of life as the genes encoding the g-globin subunit of HbF are repressed. HbF expression can provide clinical benefit to patient
Autor:
Chiara Antoniani, Fatima Amor, Elisa Magrin, Vasco Meneghini, Leslie Weber, Fulvio Mavilio, Thomas J. Cradick, Mario Amendola, Matthew H. Porteus, Annalisa Lattanzi, Tristan Felix, Marina Cavazzana, Ante Sven Lundberg, Giulia Pavani, Oriana Romano, Annarita Miccio
Publikováno v:
Blood. 128:321-321
Naturally occurring, large deletions in the β-globin locus result in increased fetal hemoglobin (HbF) expression (HPFH, Hereditary Persistence of Fetal Hemoglobin), a condition that mitigates the clinical severity of Sickle Cell Disease (SCD) and β
Autor:
Annarita Miccio, Tatjana I. Cornu, Fulvio Mavilio, Toni Cathomen, Ante Sven Lundberg, Thomas J. Cradick, Ciaran M. Lee, Matthew H. Porteus, Gang Bao
Publikováno v:
Blood. 126:3376-3376
CRISPR/Cas9 systems provide a powerful tool for precision genome editing due to their highly efficient targeting of specific DNA sequences in a genome. We have designed CRISPR single-guide RNAs (sgRNAs) containing the guide and tracr RNAs to selectiv
Autor:
Ante Sven Lundberg, Steven L. Allen
Publikováno v:
Expert opinion on investigational drugs. 20(7)
Amonafide is a novel topoisomerase II (Topo II) inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA. Amonafide retains cytotoxic activity even in the presence of P-glycoprotein (Pgp)-mediated mult
Autor:
V. Michael Holers, Ante Sven Lundberg, Trudy Wu, Sara Haven, Haifeng Wu, Shangbin Yang, Spero R. Cataland
Publikováno v:
Blood. 120:488-488
Abstract 488 Background: Acquired thrombotic thrombocytopenic purpura (TTP) is caused by acquired autoantibodies that inhibit the antithrombotic activity of ADAMTS13 and in turn cause a disseminated microangiopathy. Although, the majority of patients