Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ante S. Lundberg"'
Autor:
Yi Wang, Masha Fridkis-Hareli, Ante S. Lundberg, Nirmal K. Banda, Jeff Hunter, Michael Storek, Fang Sun, Gaurav Mehta, Richard Altman, Eran Or, Suresh Katti, Krista Johnson, Tao Peng, V. Michael Holers
Publikováno v:
Molecular Immunology. 105:150-164
Complement activation in human diseases is characterized by the local covalent deposition of the long-lived C3 fragments iC3b/C3dg/C3d. Previously, TT30, a complement alternative pathway (AP)-selective inhibitor, was designed as a fusion protein link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ea905eb539010676c87e74844d92dc
https://doi.org/10.1016/j.molimm.2018.09.013
https://doi.org/10.1016/j.molimm.2018.09.013
Autor:
Mark D. Fleming, Scott W Miller, William C. Hahn, Sheila A. Stewart, Brian Elenbaas, Kimberly A. Hartwell, John C. Olsen, Mary W. Brooks, Scott H. Randell, Robert A. Weinberg, Ante S. Lundberg
Publikováno v:
Oncogene. 21:4577-4586
One critical step in the development of a cancerous cell is its acquisition of an unlimited replicative lifespan, the process termed immortalization. Experimental model systems designed to study cellular transformation ex vivo have relied to date on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1ed3d9ee7d4473105651dfc8d8913f
https://doi.org/10.1038/sj.onc.1205550
https://doi.org/10.1038/sj.onc.1205550
Publikováno v:
Current Opinion in Cell Biology. 12:705-709
Senescence is now understood to be the final phenotypic state adopted by a cell in response to several distinct cell physiological processes, including proliferation, oncogene activation and oxygen free radical toxicity. The role of telomere maintena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d95df55c39e5cae55237909b88d1f74
https://doi.org/10.1016/s0955-0674(00)00155-1
https://doi.org/10.1016/s0955-0674(00)00155-1
Autor:
Christopher M. Counter, Ante S. Lundberg, Roderick L. Beijersbergen, Robert A. Weinberg, Mary W. Brooks, William C. Hahn
Publikováno v:
Nature. 400:464-468
During malignant transformation, cancer cells acquire genetic mutations that override the normal mechanisms controlling cellular proliferation. Primary rodent cells are efficiently converted into tumorigenic cells by the coexpression of cooperating o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d846070ed3fc0b5f0f929642ea8c2d
https://doi.org/10.1038/22780
https://doi.org/10.1038/22780
Autor:
Ante S. Lundberg, Robert A. Weinberg
Publikováno v:
Molecular and Cellular Biology. 18:753-761
The retinoblastoma protein (pRb) acts to constrain the G1-S transition in mammalian cells. Phosphorylation of pRb in G1 inactivates its growth-inhibitory function, allowing for cell cycle progression. Although several cyclins and associated cyclin-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41b73a33f29963a62d789155f8a3b8e
https://doi.org/10.1128/mcb.18.2.753
https://doi.org/10.1128/mcb.18.2.753
Autor:
Michael Mcdermott, Daniel L. Kastner, Christine Hsu, John D. Holloman, Gabriele Schmidt-Wolf, Ante S. Lundberg, Animesh A. Sinha, Hugh O. Mcdevitt, Patrick Cashin, Michael G. Molloy, Brian Mulcahy, Fergal O'Gara, Fiona I. Mcconnell, Claire Adams, Muhammad A. Khan, Frederick Wolfe, Laurence A. Rubin, Daniel O. Clegg, Dee Husebye, Christopher I. Amos, Ryk H. Ward
Publikováno v:
Arthritis & Rheumatism. 38:91-95
OBJECTIVE To evaluate the role of the T cell receptor beta chain locus (TCRB) in genetic susceptibility to rheumatoid arthritis (RA). METHODS Twenty-eight multiplex RA families were recruited from 3 rheumatology outpatient departments. All members we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e89bea0417b28a0f4d6af7513c7a1ba7
https://doi.org/10.1002/art.1780380114
https://doi.org/10.1002/art.1780380114
Autor:
V. Michael Holers, Christopher J. Horvath, Antonio M. Risitano, Masha Fridkis-Hareli, Istvan Mazsaroff, Michael Storek, Ante S. Lundberg
Publikováno v:
Blood. 118(17)
To selectively modulate human complement alternative pathway (CAP) activity implicated in a wide range of acute and chronic inflammatory conditions and to provide local cell surface and tissue-based inhibition of complement-induced damage, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa4915e4f848cca09f89b4b5f2553f9
https://pubmed.ncbi.nlm.nih.gov/22033943
https://pubmed.ncbi.nlm.nih.gov/22033943
Autor:
Hugh O. McDevitt, Ante S. Lundberg
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6545-6549
The high degree of polymorphism seen at major histocompatibility complex (MHC) class II loci is a feature unique to the MHC. Most of the beta-chain polymorphism is localized in "hypervariable" regions (HVRs). HVR amino acid sequence similarity betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2341b610dfb93052ac2f2508fbd4c6fb
https://doi.org/10.1073/pnas.89.14.6545
https://doi.org/10.1073/pnas.89.14.6545
Publikováno v:
Biopharmaceuticsdrug disposition. 31(1)
The pharmacokinetics, bioavailability and effects on electrocardiographic (ECG) parameters of fludarabine phosphate (2F-ara-AMP) were evaluated in adult patients with B-cell chronic lymphocytic leukemia. Patients received single doses of intravenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245aaabefcb9a7184cf7ec5f2a80b958
https://pubmed.ncbi.nlm.nih.gov/19862681
https://pubmed.ncbi.nlm.nih.gov/19862681
Autor:
Judith C. W. Marsh, Serena Marotta, Michael Storek, Antonio M. Risitano, Andrzej Hellmann, Austin G. Kulasekararaj, Ilene C. Weitz, Mittie K. Doyle, Modupe Elebute, Ante S. Lundberg, Leonardo Sahelijo, Casey O'Connell, Giridharan Ramsingh, Yang Dai
Publikováno v:
Blood. 126:2137-2137
TT30 is a novel, recombinant human fusion protein, linking the C3d-binding domain of human complement receptor 2 (CR2) with the complement regulatory domain of human factor H (fH). TT30 is designed to inhibit the complement alternative pathway (CAP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55b65a1000f19c39166ff4d70a4b8386
https://doi.org/10.1182/blood.v126.23.2137.2137
https://doi.org/10.1182/blood.v126.23.2137.2137