Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Antao Chang"'
Autor:
Chao Wu, Xin Yu, Xiaoling Li, Ran An, Shengnan Li, Xinyue Liu, Xiangting Hu, Shufei Li, Qinghong Zhou, Limei Li, Hai Yu, Miao Zhao, Antao Chang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 276, Iss , Pp 116302- (2024)
Benzene is a known contributor to human leukaemia through its toxic effects on bone marrow cells, and epigenetic modification is believed to be a potential mechanism underlying benzene pathogenesis. However, the specific roles of N6-methyladenosine (
Externí odkaz:
https://doaj.org/article/6293e93e4ec04f69904a66ff984319ec
Autor:
Chunhua She, Chao Wu, Weihua Guo, Yongjie Xie, Shouyi Li, Weishuai Liu, Chao Xu, Hui Li, Pei Cao, Yanfang Yang, Xiuchao Wang, Antao Chang, Yukuan Feng, Jihui Hao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Gemcitabine (GEM)-based chemotherapy is the first-line option for pancreatic ductal adenocarcinoma (PDAC). However, the development of drug resistance limits its efficacy, and the specific mechanisms remain largely unknown. RUNX1,
Externí odkaz:
https://doaj.org/article/35cb9655f284424ab326102f407ef4cd
Autor:
Danqi Fu, Jingrui Yan, Zhaoyu Zhang, Yang Liu, Xiaoqing Ma, Jinsheng Ding, Shengyu Yang, Ran Zhao, Antao Chang, Chuntao Gao, Jing Liu, Tiansuo Zhao, Xiuchao Wang, Chongbiao Huang, Song Gao, Ying Ma, Bo Tang, Yukuan Feng, Hongwei Wang, Jihui Hao
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 8, Pp 599-626 (2023)
Objective: Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant gastrointestinal cancer with a 5-year survival rate of only 9%. Of PDAC patients, 15%-20% are eligible for radical surgery. Gemcitabine is an important chemotherapeutic agent fo
Externí odkaz:
https://doaj.org/article/a41f4acb910649a6b6434c404baaece3
Autor:
Chongbiao Huang, Hui Li, Yang Xu, Chao Xu, Huizhi Sun, Zengxun Li, Yi Ge, Hongwei Wang, Tiansuo Zhao, Song Gao, Xiuchao Wang, Shengyu Yang, Peiqing Sun, Zhe Liu, Jing Liu, Antao Chang, Jihui Hao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract VEGF inhibitors are one of the most successful antiangiogenic drugs in the treatment of many solid tumors. Nevertheless, pancreatic adenocarcinoma (PAAD) cells can reinstate tumor angiogenesis via activation of VEGF-independent pathways, the
Externí odkaz:
https://doaj.org/article/f0971ada20564ff1aea7a8a80808159a
Autor:
Tianxing Zhou, Yongjie Xie, Xupeng Hou, Weiwei Bai, Xueyang Li, Ziyun Liu, Quan Man, Jingyan Sun, Danqi Fu, Jingrui Yan, Zhaoyu Zhang, Yifei Wang, Hongwei Wang, Wenna Jiang, Song Gao, Tiansuo Zhao, Antao Chang, Xiuchao Wang, Hongxia Sun, Xiufeng Zhang, Shengyu Yang, Chongbiao Huang, Jihui Hao, Jing Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-27 (2023)
Abstract Background Chemoresistance is the main reason for the poor prognosis of pancreatic ductal adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and compounds to reverse chemotherapeutic resistance. Methods We establi
Externí odkaz:
https://doaj.org/article/e32ae4b592a7470e8dd8678ad54192c9
Autor:
Liang Zhao, Min Kang, Xiaomeng Liu, Zhenran Wang, Yan Wang, Haiqiang Chen, Wenhui Liu, Shiqian Liu, Baibei Li, Chong Li, Antao Chang, Bo Tang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Glycolysis metabolism is an attractive target for cancer therapy. Reprogramming metabolic pathways could improve the ability of metabolic inhibitors to suppress cancers with limited treatment options. The ubiquitin–proteasome sy
Externí odkaz:
https://doaj.org/article/cc74f15180c44280a6559500c88ad7e6
Autor:
Chongbiao Huang, Hui Li, Yang Xu, Chao Xu, Huizhi Sun, Zengxun Li, Yi Ge, Hongwei Wang, Tiansuo Zhao, Song Gao, Xiuchao Wang, Shengyu Yang, Peiqing Sun, Zhe Liu, Jing Liu, Antao Chang, Jihui Hao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b0b9002731dd413782e9f494b437c8a8
Autor:
Weishuai Liu, Xiaozhou Yu, Yudong Yuan, Yixing Feng, Chao Wu, Chongbiao Huang, Peng Xie, Shengnan Li, Xiaofeng Li, Ziyang Wang, Lisha Qi, Yanan Chen, Lei Shi, Mulin Jun Li, Zhiyong Huang, Bo Tang, Antao Chang, Jihui Hao
Publikováno v:
Advanced Science, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract CD73, a cell surface‐bound nucleotidase, facilitates extracellular adenosine formation by hydrolyzing 5′‐AMP to adenosine. Several studies have shown that CD73 plays an essential role in immune escape, cell proliferation and tumor angi
Externí odkaz:
https://doaj.org/article/23758192030f42d88d19737b38c990d1
Autor:
Huimin Jiang, Huimin Wei, Hang Wang, Zhaoyang Wang, Jianjun Li, Yang Ou, Xuechun Xiao, Wenhao Wang, Antao Chang, Wei Sun, Li Zhao, Shuang Yang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-14 (2022)
Abstract Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator. However, how aerobic glycolysis is directly re
Externí odkaz:
https://doaj.org/article/12ab605f4b3f42a7adaf2cb8b0997ef0
Autor:
Shengnan Li, Gengpu Zhang, Yang Lu, Tiansuo Zhao, Chuntao Gao, Weishuai Liu, Yongjun Piao, Yanan Chen, Chongbiao Huang, Antao Chang, Jihui Hao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveSome patients with pancreatic ductal adenocarcinoma (PDAC) are prone to rapid recurrence or metastasis after radical resection. However, evaluation methods for effectively identifying these patients are lacking. In this study, we established
Externí odkaz:
https://doaj.org/article/23477fe56cf64da4b103f992081b649d