Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics.

Autor: Wallace RP; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Refvik KC; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Antane JT; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Brünggel K; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Tremain AC; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA., Raczy MR; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Alpar AT; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Nguyen M; Animal Resources Center, University of Chicago, Chicago, IL 60637, USA., Solanki A; Animal Resources Center, University of Chicago, Chicago, IL 60637, USA., Slezak AJ; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Watkins EA; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Lauterbach AL; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Cao S; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA., Wilson DS; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA; Biomedical Engineering Department, Johns Hopkins University, Baltimore, MD 21211, USA. Electronic address: scott.wilson@jhmi.edu., Hubbell JA; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, University of Chicago, Chicago, IL 60637, USA. Electronic address: jhubbell@uchicago.edu.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2024 Jan 16; Vol. 5 (1), pp. 101345. Date of Electronic Publication: 2023 Dec 20.

Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses.

Autor: Tremain AC; Committee on Immunology, University of Chicago, Chicago, IL, USA., Wallace RP; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Lorentz KM; Anokion US Inc., Cambridge, MA, USA., Thornley TB; Anokion US Inc., Cambridge, MA, USA., Antane JT; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Raczy MR; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Reda JW; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Alpar AT; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Slezak AJ; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Watkins EA; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Maulloo CD; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Budina E; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA., Solanki A; Animal Resources Center, University of Chicago, Chicago, IL, USA., Nguyen M; Animal Resources Center, University of Chicago, Chicago, IL, USA., Bischoff DJ; Anokion US Inc., Cambridge, MA, USA., Harrington JL; Anokion US Inc., Cambridge, MA, USA., Mishra R; Anokion US Inc., Cambridge, MA, USA., Conley GP; Anokion US Inc., Cambridge, MA, USA., Marlin R; Center for Immunology of Viral, Auto-immune, Hematological and Bacterial Diseases (IMVA-HB/IDMIT), Université Paris-Saclay, INSERM, CEA, Fontenay-aux-Roses, France., Dereuddre-Bosquet N; Center for Immunology of Viral, Auto-immune, Hematological and Bacterial Diseases (IMVA-HB/IDMIT), Université Paris-Saclay, INSERM, CEA, Fontenay-aux-Roses, France., Gallouët AS; Center for Immunology of Viral, Auto-immune, Hematological and Bacterial Diseases (IMVA-HB/IDMIT), Université Paris-Saclay, INSERM, CEA, Fontenay-aux-Roses, France., LeGrand R; Center for Immunology of Viral, Auto-immune, Hematological and Bacterial Diseases (IMVA-HB/IDMIT), Université Paris-Saclay, INSERM, CEA, Fontenay-aux-Roses, France., Wilson DS; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA. scott.wilson@jhmi.edu.; Biomedical Engineering Department, Johns Hopkins University, Baltimore, MD, USA. scott.wilson@jhmi.edu., Kontos S; Anokion US Inc., Cambridge, MA, USA., Hubbell JA; Committee on Immunology, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.; Pritzker School for Molecular Engineering, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.; Committee on Cancer Biology, University of Chicago, Chicago, IL, USA. jhubbell@uchicago.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2023 Sep; Vol. 7 (9), pp. 1142-1155. Date of Electronic Publication: 2023 Sep 07.

Semi-automated counting of axon regeneration in poly(lactide co-glycolide) spinal cord bridges.

Autor: McCreedy DA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Margul DJ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Seidlits SK; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA; Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, USA., Antane JT; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Thomas RJ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Sissman GM; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Boehler RM; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Smith DR; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Goldsmith SW; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Kukushliev TV; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Lamano JB; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Vedia BH; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., He T; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA., Shea LD; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address: ldshea@umich.edu.

Publikováno v: Journal of neuroscience methods [J Neurosci Methods] 2016 Apr 01; Vol. 263, pp. 15-22. Date of Electronic Publication: 2016 Jan 25.