Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Antanasijevic A"'
Autor:
Christopher A. Cottrell, Payal P. Pratap, Kimberly M. Cirelli, Diane G. Carnathan, Chiamaka A. Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M. Sewall, Hongmei Gao, Joel D. Allen, Bartek Nogal, Murillo Silva, Jinal Bhiman, Matthias Pauthner, Darrell J. Irvine, David Montefiori, Max Crispin, Dennis R. Burton, Guido Silvestri, Shane Crotty, Andrew B. Ward
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Immunodominance of antibodies targeting non-neutralizing epitopes and the high level of somatic hypermutation within germinal centers (GCs) required for most HIV broadly neutralizing antibodies (bnAbs) are major impediments to the developmen
Externí odkaz:
https://doaj.org/article/bdb802dbabe14d2b9e05554af9fa7556
Autor:
Yi-Nan Zhang, Jennifer Paynter, Aleksandar Antanasijevic, Joel D. Allen, Mor Eldad, Yi-Zong Lee, Jeffrey Copps, Maddy L. Newby, Linling He, Deborah Chavez, Pat Frost, Anna Goodroe, John Dutton, Robert Lanford, Christopher Chen, Ian A. Wilson, Max Crispin, Andrew B. Ward, Jiang Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-29 (2023)
Abstract Uncleaved prefusion-optimized (UFO) design can stabilize diverse HIV-1 envelope glycoproteins (Envs). Single-component, self-assembling protein nanoparticles (1c-SApNP) can display 8 or 20 native-like Env trimers as vaccine candidates. We ch
Externí odkaz:
https://doaj.org/article/8c8a86fe8b784b6ca540b12ac0e73452
Autor:
Rajesh P Ringe, Philippe Colin, Gabriel Ozorowski, Joel D Allen, Anila Yasmeen, Gemma E Seabright, Jeong Hyun Lee, Aleksandar Antanasijevic, Kimmo Rantalainen, Thomas Ketas, John P Moore, Andrew B Ward, Max Crispin, P J Klasse
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011601 (2023)
Neutralizing antibodies (NAbs) to multiple epitopes on the HIV-1-envelope glycoprotein (Env) have been isolated from infected persons. The potency of NAbs is measured more often than the size of the persistent fraction of infectivity at maximum neutr
Externí odkaz:
https://doaj.org/article/7568988b535a466f9fbb76d93f1b2ea9
Akademický článek
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Autor:
Hannah L. Turner, Abigail M. Jackson, Sara T. Richey, Leigh M. Sewall, Aleksandar Antanasijevic, Lars Hangartner, Andrew B. Ward
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102476- (2023)
Summary: Electron microscopy-based polyclonal epitope mapping (EMPEM) can delineate epitope specificities of serum antibodies to a given antigen following vaccination or infection. Here, we present a protocol for the EMPEM method for rapid high-throu
Externí odkaz:
https://doaj.org/article/010e64234a784042945307e4df01eeb0
Autor:
Perrett, Hailee R., Brouwer, Philip J.M., Hurtado, Jonathan, Newby, Maddy L., Liu, Lin, Müller-Kräuter, Helena, Müller Aguirre, Sarah, Burger, Judith A., Bouhuijs, Joey H., Gibson, Grace, Messmer, Terrence, Schieffelin, John S., Antanasijevic, Aleksandar, Boons, Geert-Jan, Strecker, Thomas, Crispin, Max, Sanders, Rogier W., Briney, Bryan, Ward, Andrew B.
Publikováno v:
In Cell Reports 30 May 2023 42(5)
Autor:
E. I. M. M. Reiss, M. M. van Haaren, J. van Schooten, M. A. F. Claireaux, P. Maisonnasse, A. Antanasijevic, J. D. Allen, I. Bontjer, J. L. Torres, W-H Lee, G. Ozorowski, N. Vázquez Bernat, M. Kaduk, Y. Aldon, J. A. Burger, H. Chawla, A. Aartse, M. Tolazzi, H. Gao, P. Mundsperger, M. Crispin, D. C. Montefiori, G. B. Karlsson Hedestam, G. Scarlatti, A. B. Ward, R. Le Grand, R. Shattock, N. Dereuddre-Bosquet, R. W. Sanders, M. J. van Gils
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract The HIV-1 envelope glycoprotein (Env) trimer is the key target for vaccines aimed at inducing neutralizing antibodies (NAbs) against HIV-1. The clinical candidate immunogen ConM SOSIP.v7 is a stabilized native-like HIV-1 Env trimer based on
Externí odkaz:
https://doaj.org/article/d919d26129cb4d55a6a5afbc08a9a26e
Autor:
Hailee R. Perrett, Philip J.M. Brouwer, Jonathan Hurtado, Maddy L. Newby, Lin Liu, Helena Müller-Kräuter, Sarah Müller Aguirre, Judith A. Burger, Joey H. Bouhuijs, Grace Gibson, Terrence Messmer, John S. Schieffelin, Aleksandar Antanasijevic, Geert-Jan Boons, Thomas Strecker, Max Crispin, Rogier W. Sanders, Bryan Briney, Andrew B. Ward
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112524- (2023)
Summary: Lassa fever is an acute hemorrhagic fever caused by the zoonotic Lassa virus (LASV). The LASV glycoprotein complex (GPC) mediates viral entry and is the sole target for neutralizing antibodies. Immunogen design is complicated by the metastab
Externí odkaz:
https://doaj.org/article/42bc3a303aa044c8bb858af2181c5575
Autor:
Kraft, John C., Pham, Minh N., Shehata, Laila, Brinkkemper, Mitch, Boyoglu-Barnum, Seyhan, Sprouse, Kaitlin R., Walls, Alexandra C., Cheng, Suna, Murphy, Mike, Pettie, Deleah, Ahlrichs, Maggie, Sydeman, Claire, Johnson, Max, Blackstone, Alyssa, Ellis, Daniel, Ravichandran, Rashmi, Fiala, Brooke, Wrenn, Samuel, Miranda, Marcos, Sliepen, Kwinten, Brouwer, Philip J.M., Antanasijevic, Aleksandar, Veesler, David, Ward, Andrew B., Kanekiyo, Masaru, Pepper, Marion, Sanders, Rogier W., King, Neil P.
Publikováno v:
In Cell Reports Medicine 18 October 2022 3(10)
Autor:
Brouwer, Philip J.M., Antanasijevic, Aleksandar, Ronk, Adam J., Müller-Kräuter, Helena, Watanabe, Yasunori, Claireaux, Mathieu, Perrett, Hailee R., Bijl, Tom P.L., Grobben, Marloes, Umotoy, Jeffrey C., Schriek, Angela I., Burger, Judith A., Tejjani, Khadija, Lloyd, Nicole M., Steijaert, Thijs H., van Haaren, Marlies M., Sliepen, Kwinten, de Taeye, Steven W., van Gils, Marit J., Crispin, Max, Strecker, Thomas, Bukreyev, Alexander, Ward, Andrew B., Sanders, Rogier W.
Publikováno v:
In Cell Host & Microbe October 2022