Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anta Ngkelo"'
NK1.1+ Cells and CD8+ T Cells Mediate the Antitumor Activity of Cl-IB-MECA in a Mouse Melanoma Model
Autor:
Silvana Morello, Rosalinda Sorrentino, Antonella Montinaro, Antonio Luciano, Piera Maiolino, Anta Ngkelo, Claudio Arra, Ian M. Adcock, Aldo Pinto
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 365-373 (2011)
Cl-IB-MECA, synthetic A3 adenosine receptor agonist, is a potential anticancer agent. In this study, we have examined the effect of Cl-IB-MECA in a mouse melanoma model. Cl-IB-MECA significantly inhibited tumor growth in immune-competent mice. Notabl
Externí odkaz:
https://doaj.org/article/8d44ec819fdf4534bf85abe8caa5636d
Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction
Autor:
Luca Danelli, Maxime Branchereau, Eric Camerer, Mathilde Lemitre, Nisa Renault, Béatrice Cousin, Pauline Marck, Adèle Richart, Elodie Luche, Pierre Launay, Sylvain M. Le Gall, Coralie L. Guerin, Jean-Sébastien Silvestre, Anta Ngkelo, Philippe Bonnin, Anaïs Kervadec, Jonathan A. Kirk, Hans Reimer Rodewald, Philippe Menasché, Mark J. Ranek, Patrick Bruneval, Christophe Heymes, José Vilar, Ulrich Blank, David A. Kass, Gregory Gautier, Louis Casteilla
Publikováno v:
The Journal of Experimental Medicine
Ngkelo et al. use a mast cell–deficient mouse model to reveal a protective role of mast cells in myocardial infarction, through regulation of the cardiac contractile machinery.
Acute myocardial infarction (MI) is a severe ischemic disease resp
Acute myocardial infarction (MI) is a severe ischemic disease resp
Autor:
Ivana Zlatanova, Christian Stockmann, Ziad Mallat, Jean-Sébastien Silvestre, Cristina Pinto, Marie Rouanet, José Vilar, Clément Cochain, Mathilde Lemitre, Anta Ngkelo, Kiave-Yune Howangyin, Bernd K. Fleischmann
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background— In infarcted heart, improper clearance of dying cells by activated neighboring phagocytes may precipitate the transition to heart failure. We analyzed the coordinated role of 2
Background— In infarcted heart, improper clearance of dying cells by activated neighboring phagocytes may precipitate the transition to heart failure. We analyzed the coordinated role of 2
Autor:
Nathalie Kubis, Philippe Bonnin, Bernard I. Levy, Diana Cifuentes, Anta Ngkelo, Marine Poittevin, Tatyana Merkulova-Rainon
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 70(3)
The epidemiological link between hypertension and Alzheimer disease is established. We previously reported that hypertension aggravates the Alzheimer-like pathology in APPPS1 mice (amyloid precursor protein/presenilin-1, mouse model of Alzheimer dise
Autor:
Anta Ngkelo, Jonathan Kirk, Adele Richart, Philippe Bonnin, Jose Vilar, Christophe Heymes, Hans-Reimer Rodewald, David Kass, Jean-Sebastien Silvestre
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Inflammatory cells orchestrate post-ischemic cardiac remodeling after myocardial infarction (MI). Studies in Kit mutant mice suggest key roles for mast cells in post-ischemic tissue remodeling. However, Kit mutations affect multiple cell types of bot
Autor:
Michel Pucéat, Anta Ngkelo, Tui Neri, Jean-Sébastien Silvestre, Xavier Loyer, Bernard Levy, Marc E. Rothenberg, Adèle Richart, José Vilar, Ziad Mallat, Kiave Yune Howangyin, Marie Rouanet, Coralie L. Guerin, Wineke Bakker, Ivana Zlatanova
Publikováno v:
Stem cells (Dayton, Ohio). 32(11)
Published clinical trials in patients with ischemic diseases show limited benefit of adult stem cell-based therapy, likely due to their restricted plasticity and commitment toward vascular cell lineage. We aim to uncover the potent regenerative abili
Autor:
Ian M. Adcock, Anta Ngkelo
Publikováno v:
Current opinion in pharmacology. 13(3)
Chronic obstructive pulmonary disease (COPD) is a major health problem worldwide. It is characterised by chronic inflammation in the lungs that leads to progressive chronic airflow obstruction. The main strategy for treating COPD is control of the ch
Publikováno v:
Journal of Inflammation (London, England)
Journal of Inflammation, Vol 9, Iss 1, p 1 (2012)
Journal of Inflammation, Vol 9, Iss 1, p 1 (2012)
COPD is a disease of innate immunity and bacterial infections are a dominant cause of exacerbations in the later stages resulting in poor health and high mortality. The pathogen-associated molecular pattern (PAMP) lipopolysaccharide (LPS) is sensed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a73043d9d7e3d97c3c5aeaa1176803
http://hdl.handle.net/10044/1/31728
http://hdl.handle.net/10044/1/31728
Publikováno v:
B33. OXIDANTS, OXIDASES AND REDOX REGULATION OF LUNG DISEASE.
Autor:
Aldo Pinto, Piera Maiolino, Rosalinda Sorrentino, Claudio Arra, Silvana Morello, Antonella Montinaro, Antonio Luciano, Anta Ngkelo, Ian M. Adcock
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 365-373 (2011)
Cl-IB-MECA, synthetic A(3) adenosine receptor agonist, is a potential anticancer agent. In this study, we have examined the effect of Cl-IB-MECA in a mouse melanoma model. Cl-IB-MECA significantly inhibited tumor growth in immune-competent mice. Nota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f556460ef3353b3699376f9b90bece
http://hdl.handle.net/11386/3023159
http://hdl.handle.net/11386/3023159