Mycobacterium tuberculosis and M. bovis BCG Moreau Fumarate Reductase Operons Produce Different Polypeptides That May Be Related to Non-canonical Functions

Autor: Marcos Gustavo Araujo Schwarz, Deborah Antunes, Paloma Rezende Corrêa, Antônio José da Silva-Gonçalves, Wladimir Malaga, Ernesto Raul Caffarena, Christophe Guilhot, Leila Mendonça-Lima

Publikováno v: Frontiers in Microbiology, Vol 11 (2021)

Tuberculosis is a world widespread disease, caused by Mycobacterium tuberculosis (M.tb). Although considered an obligate aerobe, this organism can resist life-limiting conditions such as microaerophily mainly due to its set of enzymes responsible for

Externí odkaz: https://doaj.org/article/626174fdadcc4b0baede5747c8d1d166

Zika Virus Infects Human Placental Mast Cells and the HMC-1 Cell Line, and Triggers Degranulation, Cytokine Release and Ultrastructural Changes

Autor: Kíssila Rabelo, Antônio José da Silva Gonçalves, Luiz José de Souza, Anna Paula Sales, Sheila Maria Barbosa de Lima, Gisela Freitas Trindade, Bianca Torres Ciambarella, Natália Recardo Amorim Tasmo, Bruno Lourenço Diaz, Jorge José de Carvalho, Márcia Pereira de Oliveira Duarte, Marciano Viana Paes

Publikováno v: Cells, Vol 9, Iss 4, p 975 (2020)

Zika virus (ZIKV) is an emergent arthropod-borne virus whose outbreak in Brazil has brought major public health problems. Infected individuals have different symptoms, including rash and pruritus, which can be relieved by the administration of antial

Externí odkaz: https://doaj.org/article/ed9961310f5548e38c4a87450520eab4

Mycobacterium tuberculosis and M. bovis BCG Moreau Fumarate Reductase Operons Produce Different Polypeptides That May Be Related to Non-canonical Functions

Autor: Leila Mendonça-Lima, Wladimir Malaga, Christophe Guilhot, Deborah Antunes, Ernesto Raul Caffarena, Marcos Gustavo Araujo Schwarz, Paloma Rezende Correa, Antônio José da Silva-Gonçalves

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Frontiers Media, 2021, 11, pp.624121. ⟨10.3389/fmicb.2020.624121⟩
Frontiers in Microbiology, Vol 11 (2021)

Tuberculosis is a world widespread disease, caused by Mycobacterium tuberculosis (M.tb). Although considered an obligate aerobe, this organism can resist life-limiting conditions such as microaerophily mainly due to its set of enzymes responsible for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bfd8e123dceafcea159952560bec9b
https://doi.org/10.3389/fmicb.2020.624121

New administration model of trans-chalcone biodegradable polymers for the treatment of experimental leishmaniasis

Autor: Isabel L. Bazzocchi, Antônio José da Silva-Gonçalves, Alexis Oliva, Antonio Perera, Basilio Valladares, Leonor L. Leon, Rosane Maria Temporal, José E. Piñero, Ignacio A. Jiménez

Publikováno v: Acta tropica. 98(1)

The present study was designed to investigate a new administration model and the antileishmanial activity of a semi-synthetic chalcone, benzylideneacetophenone (trans-chalcone). The antileishmanial activity of this product was first tested in vitro a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2565d51c2da22a4e6865d15d6184c158
https://pubmed.ncbi.nlm.nih.gov/16529707

Effects of amidine derivatives on parasite-macrophage interaction and evaluation of toxicity

Autor: Claude Pirmez, Aurea Echevarria, Lenor L. Leon, Marco A. S. de Souza, Antônio José da Silva-Gonçalves, Mônica Sertã, Léa Cysne-Finkelstein, Rosane Maria Temporal

Publikováno v: Arzneimittel-Forschung. 52(6)

In this work, the effect of amidine derivatives (with bromine and methoxy as substituents) in the "in vitro" parasite-macrophage interaction was evaluated. The potential toxicity was also analyzed. The results show that the methoxy-derivative was abl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d92ba816f143751e9a15b243f0eeaa2
https://pubmed.ncbi.nlm.nih.gov/12109051