Zobrazeno 1 - 10
of 18
pro vyhledávání: '"António J. M. Santos"'
Publikováno v:
Trends in Cell Biology. 28:1062-1078
The intestinal epithelium is a rapidly renewing cellular compartment. This constant regeneration is a hallmark of intestinal homeostasis and requires a tightly regulated balance between intestinal stem cell (ISC) proliferation and differentiation. Si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed09445d9e60a75ba856597654d772d
https://doi.org/10.1016/j.tcb.2018.08.001
https://doi.org/10.1016/j.tcb.2018.08.001
Autor:
Pehr B. Harbury, Grace X.Y. Zheng, Solongo B. Ziraldo, Lisa E. Wagar, Tarjei S. Mikkelsen, Manuel R. Amieva, Jihang Ju, Calvin J. Kuo, Mar Margalef-Català, Jeffrey S. Glenn, Daniel J. Hart, Mark M. Davis, Arpit Batish, Caitlin E. Edwards, Ameen A. Salahudeen, Arjun Rustagi, Catherine A. Blish, Sean M. de la O, Shannon S. Choi, Monica Nagendran, Ralph S. Baric, Vincent C. Luca, Junjie Zhu, Tushar J. Desai, Khanh Nguyen, Jessica M. Terry, Tatsuya Usui, Phillip Belgrader, Ryan A. Flynn, Vincent van Unen, Chiara Sabatti, Benedict Anchang, K. Christopher Garcia, António J. M. Santos
Publikováno v:
Nature
The distal lung contains terminal bronchioles and alveoli that facilitate gas exchange and is affected by disorders including interstitial lung disease, cancer, and SARS-CoV-2-associated COVID-19 pneumonia. Investigations of these localized pathologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd135e8a48676b74a1913575886480b
https://pubmed.ncbi.nlm.nih.gov/33238290
https://pubmed.ncbi.nlm.nih.gov/33238290
Autor:
Francisco S Mesquita, Mair Thomas, Martin Sachse, António J M Santos, Rita Figueira, David W Holden
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002743 (2012)
Cell stress and infection promote the formation of ubiquitinated aggregates in both non-immune and immune cells. These structures are recognised by the autophagy receptor p62/sequestosome 1 and are substrates for selective autophagy. The intracellula
Externí odkaz:
https://doaj.org/article/a511cd1048664a6690244cc63c80a22f
Autor:
Sanne de Haan, Kathrin Rösch, Roeland Nusse, Cayetano Pleguezuelos-Manzano, Jeroen P. Roose, Carol Piani, Kanako Yuki, Calvin J. Kuo, David Baker, Jacob Piehler, Changjiang You, António J. M. Santos, Jens Puschhof, Wieger Hemrika, Jarno Drost, Sylvia F. Boj, Hans Clevers, K. Christopher Garcia, Oghenekevwe M. Gbenedio, Melanie Ott, Ramazan Senlice, Wim de Lau, Jenny Yuan, Mario Vallon, Philippe Depeille, Weng Chuan Peng, Sean M. Wu, Claudia Y. Janda, Maarten H. Geurts, Andrew C.T. Ha, Luke T. Dang, Jan W. Buikema, Yi Miao
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 27(5), 840-851.e6. Cell Press
Cell Stem Cell, 27(5), 840-851.e6. Cell Press
Modulation of Wnt signaling has untapped potential in regenerative medicine due to its essential functions in stem cell homeostasis. However, Wnt lipidation and Wnt-Frizzled (Fzd) cross-reactivity have hindered translational Wnt applications. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b232938f6dd6d1f94761d2a2d4d248
https://pubmed.ncbi.nlm.nih.gov/32818433
https://pubmed.ncbi.nlm.nih.gov/32818433
Autor:
Maria Ortega-Bellido, Ombretta Foresti, Ishier Raote, Felix Campelo, Vivek Malhotra, Maria F. Garcia-Parajo, António J. M. Santos, Chong Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d7b0b8ca4a774cdab156ca6ac8da00
https://doi.org/10.7554/elife.32723.025
https://doi.org/10.7554/elife.32723.025
Autor:
Maria F. Garcia-Parajo, Felix Campelo, Ishier Raote, Maria Ortega-Bellido, Ombretta Foresti, Vivek Malhotra, António J. M. Santos, Chong Zhang
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
eLife
Recercat. Dipósit de la Recerca de Catalunya
instname
eLife, Vol 7 (2018)
Universitat Politècnica de Catalunya (UPC)
eLife
Recercat. Dipósit de la Recerca de Catalunya
instname
eLife, Vol 7 (2018)
Collagen export from the endoplasmic reticulum (ER) requires TANGO1, COPII coats, and retrograde fusion of ERGIC membranes. How do these components come together to produce a transport carrier commensurate with the bulky cargo collagen? TANGO1 is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb8d777cbe0a76bd9b8647aa2e90ffb
http://hdl.handle.net/2117/114925
http://hdl.handle.net/2117/114925
Autor:
Emmanuel Boucrot, António J. M. Santos
Publikováno v:
Clathrin-Mediated Endocytosis ISBN: 9781493987177
Endocytosis mediates the cellular uptake of nutrients, modulates signaling by regulating levels of cell surface receptors, and is usurped by pathogens during infection. Endocytosis activity is known to vary during the cell cycle, in particular during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf76b3743d6276c5e179de3425601605
https://doi.org/10.1007/978-1-4939-8719-1_3
https://doi.org/10.1007/978-1-4939-8719-1_3
Autor:
Mar Margalef-Català, Caitlin E. Edwards, Manuel R. Amieva, Jihang Ju, Lisa E. Wagar, Arjun Rustagi, Khanh Nguyen, Vincent C. Luca, Tatsuya Usui, Ameen A. Salahudeen, Tarjei S. Mikkelsen, Shannon S. Choi, Ralph S. Baric, António J. M. Santos, Jessica M. Terry, Grace X.Y. Zheng, Mark M. Davis, Catherine A. Blish, Ryan A. Flynn, Phillip Belgrader, Solongo B. Ziraldo, Vincent van Unen, Jeffrey S. Glenn, Junjie Zhu, Sean M. de la O, Monica Nagendran, Tushar J. Desai, Calvin J. Kuo, Arpit Batish, Benedict Anchang, K. Christopher Garcia, Daniel J. Hart, Pehr B. Harbury, Chiara Sabatti
Publikováno v:
bioRxiv
Nature
Nature
The distal lung contains terminal bronchioles and alveoli that facilitate gas exchange and is affected by disorders including interstitial lung disease, cancer, and SARS-CoV-2-associated COVID-19 pneumonia. Investigations of these localized pathologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c696214f38cd47aec02a747ccb7cb29
https://pubmed.ncbi.nlm.nih.gov/32743583
https://pubmed.ncbi.nlm.nih.gov/32743583
Autor:
Paulo B. Correia, Karina B. Xavier, Michal Bejerano-Sagie, Catarina S. Pereira, António J. M. Santos, João C. Marques
Publikováno v:
Molecular Microbiology. 84:93-104
Autoinducer-2 (AI-2) a signal produced by a range of phylogenetically distant microorganisms, enables inter-species cell-cell communication and regulates many bacterial phenotypes. Certain bacteria can interfere with AI-2-regulated behaviours of neig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8fed4c8fa4f7c19feb912537ec0d5d5
https://doi.org/10.1111/j.1365-2958.2012.08010.x
https://doi.org/10.1111/j.1365-2958.2012.08010.x