Zobrazeno 1 - 10
of 111
pro vyhledávání: '"António G. Castro"'
Autor:
Daniel B. Rodrigues, Helena R. Moreira, Mariana T. Cerqueira, Alexandra P. Marques, António G. Castro, Rui L. Reis, Rogério P. Pirraco
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-19 (2022)
Abstract Background T cell priming has been shown to be a powerful immunotherapeutic approach for cancer treatment in terms of efficacy and relatively weak side effects. Systems that optimize the stimulation of T cells to improve therapeutic efficacy
Externí odkaz:
https://doaj.org/article/9e240c53884d402faeacec8e70cfcb61
Autor:
Catarina M. Ferreira, Ana Margarida Barbosa, Palmira Barreira-Silva, Ricardo Silvestre, Cristina Cunha, Agostinho Carvalho, Fernando Rodrigues, Margarida Correia-Neves, António G. Castro, Egídio Torrado
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Cytokine-producing CD4+ T cells play a crucial role in the control of Mycobacterium tuberculosis infection; however, there is a delayed appearance of effector T cells in the lungs following aerosol infection. The immunomodulatory cytokine IL-10 antag
Externí odkaz:
https://doaj.org/article/35c15db18b774497a118c4122f4e11f5
Autor:
Ana Margarida Barbosa, Olga Martinho, Rosete Nogueira, Juliana Campos, Liliana Lobo, Henrique Pinto, Adhemar Longatto-Filho, António G. Castro, Sandra F. Martins, Egídio Torrado
Publikováno v:
Biology, Vol 10, Iss 8, p 808 (2021)
Tumor-infiltrating lymphocytes include heterogeneous populations of T lymphocytes that play crucial roles in the tumor immune response; importantly, their presence in the tumor tissue may predict clinical outcomes. Therefore, we herein studied the pr
Externí odkaz:
https://doaj.org/article/50e3c04807374406a7264ca48bb9d662
Autor:
Kiranmai Bhatt, Henrique Machado, Nuno S. Osório, Jeremy Sousa, Filipa Cardoso, Carlos Magalhães, Bing Chen, Mei Chen, John Kim, Albel Singh, Catarina M. Ferreira, António G. Castro, Egidio Torrado, William R. Jacobs, Apoorva Bhatt, Margarida Saraiva
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Nonribosomal peptide synthases produce short peptides in a manner that is distinct from classical mRNA-dependent ribosome-mediated translation. The Mycobacterium tuberculosis genome harbors a nonribosomal peptide synthase gene, nrp, which is
Externí odkaz:
https://doaj.org/article/1ca69f777d56487ab7f418ab4f795bf6
Autor:
Joana Gaifem, Luís G. Gonçalves, Ricardo J. Dinis-Oliveira, Cristina Cunha, Agostinho Carvalho, Egídio Torrado, Fernando Rodrigues, Margarida Saraiva, António G. Castro, Ricardo Silvestre
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Dietary nutrients have emerged as potential therapeutic adjuncts for inflammatory bowel disease (IBD) given their impact on intestinal homeostasis through the modulation of immune response, gut microbiota composition and epithelial barrier stability.
Externí odkaz:
https://doaj.org/article/24c3a209f76b403c96121bbcb81cc4e6
Publikováno v:
Pathobiology. 88:170-186
The immune system plays a critical role in preventing cancer development and progression. However, the complex network of cells and soluble factor that form the tumor microenvironment (TME) can dictate the differentiation of tumor-infiltrating leukoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcb0e745a599cfa6fa68537f6beb9c4
https://doi.org/10.1159/000512326
https://doi.org/10.1159/000512326
Autor:
Teresa Carvalho, Albel Singh, Jeremy Sousa, Luisa Simoes-Costa, Álvaro Chiner-Oms, Leandro Barros, Nuno S. Osório, Apoorva Bhatt, Cristina P. Vieira, Baltazar Cá, Maria Isabel Veiga, António G. Castro, Ana Raquel Maceiras, Sebastien Gagneux, Ana Isabel Rodrigues Fernandes, João Tiago Guimarães, António Amorim, Iñaki Comas, Helder Novais Bastos, Kaori L. Fonseca, Pedro Rodrigues, Carlos Magalhães, Margarida Saraiva, Rui Pereira, Angélica Ramos, Jorge Vieira, Fernando Rodrigues, Henrique Machado
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
14 páginas, 6 figuras. Supplementary information is available for this paper at https://doi.org/10.1038/s41467-020-15832-6. Sequence data are deposited on NCBI GEO database with the accession code GSE138580
Genetic diversity of Mycobacterium tu
Genetic diversity of Mycobacterium tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d0ff58581a69d4e8619e55fe908bc3
http://link.springer.com/article/10.1038/s41467-020-15832-6
http://link.springer.com/article/10.1038/s41467-020-15832-6
Autor:
Ibrahim Fatih Cengiz, Joaquim M. Oliveira, António G. Castro, Maurice N. Collins, Rui L. Reis, Fernanda Zamboni, Ana Margarida Barbosa
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Pharmaceutics, Vol 13, Iss 1925, p 1925 (2021)
Pharmaceutics
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Pharmaceutics, Vol 13, Iss 1925, p 1925 (2021)
Pharmaceutics
Supplementary Materials: The following are available online at https://www.mdpi.com/article/10 .3390/pharmaceutics13111925/s1. Figure S1 (A) Intraperitoneal injection of STZ. (B) Mice are kept in cages with ad libitum fed regimen. Figure S2 MIN-6 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6311ad3cfbb161c656f09ceaf9ae3
Autor:
Palmira Barreira-Silva, António G. Castro, Agostinho Carvalho, Egídio Torrado, Margarida Correia-Neves, Cristina Cunha, Fernando Rodrigues, Catarina Machado Ferreira, Ricardo Silvestre, Ana Margarida Barbosa
Publikováno v:
JCI Insight
Cytokine-producing CD4+ T cells play a crucial role in the control of Mycobacterium tuberculosis infection; however, there is a delayed appearance of effector T cells in the lungs following aerosol infection. The immunomodulatory cytokine IL-10 antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c3666120adb179e5084518fa13bbfc
https://doi.org/10.1172/jci.insight.150060
https://doi.org/10.1172/jci.insight.150060
Autor:
Ana, Cardoso, Ana Catarina, Martins, Ana Raquel, Maceiras, Wei, Liu, Isabel, Castro, António G, Castro, António, Bandeira, James P, Di Santo, Ana, Cumano, Yan, Li, Paulo, Vieira, Margarida, Saraiva
Publikováno v:
Cell Reports
Cell Reports, 2021, 37 (4), pp.109887. ⟨10.1016/j.celrep.2021.109887⟩
Cell Reports, Elsevier Inc, 2021, 37 (4), pp.109887. ⟨10.1016/j.celrep.2021.109887⟩
Cell Reports, 2021, 37 (4), pp.109887. ⟨10.1016/j.celrep.2021.109887⟩
Cell Reports, Elsevier Inc, 2021, 37 (4), pp.109887. ⟨10.1016/j.celrep.2021.109887⟩
International audience; In emergency myelopoiesis (EM), expansion of the myeloid progenitor compartment and increased myeloid cell production are observed and often mediated by the pro-inflammatory cytokine interferon gamma (IFN-γ). Interleukin-10 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b2c03464de8d68dd47090656ab5584a3
https://hal-pasteur.archives-ouvertes.fr/pasteur-03405881
https://hal-pasteur.archives-ouvertes.fr/pasteur-03405881