Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Daniel Haensel, Bence Daniel, Sadhana Gaddam, Cory Pan, Tania Fabo, Jeremy Bjelajac, Anna R. Jussila, Fernanda Gonzalez, Nancy Yanzhe Li, Yun Chen, JinChao Hou, Tiffany Patel, Sumaira Aasi, Ansuman T. Satpathy, Anthony E. Oro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Cancer immunotherapies have revolutionized treatment but have shown limited success as single-agent therapies highlighting the need to understand the origin, assembly, and dynamics of heterogeneous tumor immune niches. Here, we use single-ce
Externí odkaz:
https://doaj.org/article/5e4bc24e6e914f23800da67601a21438
Autor:
Sarthak Sinha, Ansuman T. Satpathy, Weiqiang Zhou, Hongkai Ji, Jo A. Stratton, Arzina Jaffer, Nizar Bahlis, Sorana Morrissy, Jeff A. Biernaskie
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 172-190 (2021)
How distinct transcriptional programs are enacted to generate cellular heterogeneity and plasticity, and enable complex fate decisions are important open questions. One key regulator is the cell’s epigenome state that drives distinct transcriptiona
Externí odkaz:
https://doaj.org/article/5aca11c01c014409a829dd0a2d1013a8
Autor:
Qian Liu, Lisa C. Zaba, Ansuman T. Satpathy, Michelle Longmire, Wen Zhang, Kun Li, Jeffrey Granja, Chuang Guo, Jun Lin, Rui Li, Karen Tolentino, Gabriela Kania, Oliver Distler, David Fiorentino, Lorinda Chung, Kun Qu, Howard Y. Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Systemic sclerosis (SSc) is a disease with manifestation in the skin and immune etiology, but the pathogenic immune cell types remain unidentified. Here the authors use ATAC-seq to profile chromatin landscapes of skin samples from patients with SSc t
Externí odkaz:
https://doaj.org/article/136a9ffc01a74f60ae540dd0b3a7288f
Autor:
Jason D. Goldman, Kai Wang, Katharina Röltgen, Sandra C. A. Nielsen, Jared C. Roach, Samia N. Naccache, Fan Yang, Oliver F. Wirz, Kathryn E. Yost, Ji-Yeun Lee, Kelly Chun, Terri Wrin, Christos J. Petropoulos, Inyoul Lee, Shannon Fallen, Paula M. Manner, Julie A. Wallick, Heather A. Algren, Kim M. Murray, Jennifer Hadlock, Daniel Chen, Chengzhen L. Dai, Dan Yuan, Yapeng Su, Joshua Jeharajah, William R. Berrington, George P. Pappas, Sonam T. Nyatsatsang, Alexander L. Greninger, Ansuman T. Satpathy, John S. Pauk, Scott D. Boyd, James R. Heath
Publikováno v:
Vaccines, Vol 11, Iss 1, p 5 (2022)
Recovery from COVID-19 is associated with production of anti-SARS-CoV-2 antibodies, but it is uncertain whether these confer immunity. We describe viral RNA shedding duration in hospitalized patients and identify patients with recurrent shedding. We
Externí odkaz:
https://doaj.org/article/be3f6b053d0240218091cbfe8d12b18b
Autor:
Elena López-Isac, Marialbert Acosta-Herrera, Martin Kerick, Shervin Assassi, Ansuman T. Satpathy, Jeffrey Granja, Maxwell R. Mumbach, Lorenzo Beretta, Carmen P. Simeón, Patricia Carreira, Norberto Ortego-Centeno, Ivan Castellvi, Lara Bossini-Castillo, F. David Carmona, Gisela Orozco, Nicolas Hunzelmann, Jörg H. W. Distler, Andre Franke, Claudio Lunardi, Gianluca Moroncini, Armando Gabrielli, Jeska de Vries-Bouwstra, Cisca Wijmenga, Bobby P. C. Koeleman, Annika Nordin, Leonid Padyukov, Anna-Maria Hoffmann-Vold, Benedicte Lie, European Scleroderma Group, Susanna Proudman, Wendy Stevens, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Timothy Vyse, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Yannick Allanore, Matthew A. Brown, Timothy R. D. J. Radstake, Carmen Fonseca, Howard Y. Chang, Maureen D. Mayes, Javier Martin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Systemic sclerosis (SSc) is a heterogeneous chronic autoimmune disease that affects the connective tissue. Here, López-Isac et al. identify 13 new risk loci for SSc as well as loci specific for limited cutaneous and diffuse SSc and, defining credibl
Externí odkaz:
https://doaj.org/article/2c83b5b19dd94142a96da7824aa29e78
Autor:
Adi Nagler, Shelly Kalaora, Chaya Barbolin, Anastasia Gangaev, Steven L.C. Ketelaars, Michal Alon, Joy Pai, Gil Benedek, Yfat Yahalom-Ronen, Noam Erez, Polina Greenberg, Gal Yagel, Aviyah Peri, Yishai Levin, Ansuman T. Satpathy, Erez Bar-Haim, Nir Paran, Pia Kvistborg, Yardena Samuels
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109305- (2021)
Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antige
Externí odkaz:
https://doaj.org/article/359efd361f4c4d7896a96b9b39e85d68
Autor:
Rebecca Leylek, Marcela Alcántara-Hernández, Jeffrey M. Granja, Michael Chavez, Kimberly Perez, Oscar R. Diaz, Rui Li, Ansuman T. Satpathy, Howard Y. Chang, Juliana Idoyaga
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108180- (2020)
Summary: Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive. Here, we analyze global chromatin accessibility profiles acros
Externí odkaz:
https://doaj.org/article/81883882618e42bc9e0d0395ae8e2a79
Autor:
Qian Liu, Lisa C. Zaba, Ansuman T. Satpathy, Michelle Longmire, Wen Zhang, Kun Li, Jeffrey Granja, Chuang Guo, Jun Lin, Rui Li, Karen Tolentino, Gabriela Kania, Oliver Distler, David Fiorentino, Lorinda Chung, Kun Qu, Howard Y. Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20411-w
Externí odkaz:
https://doaj.org/article/d81da064a5fc409a9e54505d28dd4e00
Autor:
Tian-Tian Liu, Feiya Ou, Julia A. Belk, Prachi Bagadia, David A. Anderson, Vivek Durai, Winnie Yao, Ansuman T. Satpathy, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Genes & Development. 37:291-302
Individual elements within a superenhancer can act in a cooperative or temporal manner, but the underlying mechanisms remain obscure. We recently identified anIrf8superenhancer, within which different elements act at distinct stages of type 1 classic
Autor:
Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh, Lea Wenting Rysavy, Won-Ju Kim, Caleb Lareau, Elena Sotillo, Evan W. Weber, Skyler P. Rietberg, Guillermo Nicolas Dalton, Yajie Yin, Dorota Klysz, Peng Xu, Eva L. de la Serna, Alexander R. Dunn, Ansuman T. Satpathy, Crystal L. Mackall, Robbie G. Majzner
Publikováno v:
Nature. 615:507-516