Pancreatic Secretory Trypsin Inhibitor (SPINK1) Gene Mutation in Patients with Acute Alcohol Pancreatitis (AAP) Compared to Healthy Controls and Heavy Alcohol Users without Pancreatitis.

Autor: Anssi, Nikkola^1,2 (AUTHOR), Antero, Mäkelä Kari³ (AUTHOR), Karl-Heinz, Herzig^3,4,5 (AUTHOR), Jagalur, Mutt Shivaprakash³ (AUTHOR), Aishwarya, Prasannan³ (AUTHOR), Hanna, Seppänen⁶ (AUTHOR), Terho, Lehtimäki^2,7,8 (AUTHOR), Mika, Kähönen^2,8,9 (AUTHOR), Olli, Raitakari^10,11,12 (AUTHOR), Ilkka, Seppälä⁷ (AUTHOR), Pihla, Pakkanen^2,13 (AUTHOR), Isto, Nordback² (AUTHOR), Juhani, Sand¹ (AUTHOR), Johanna, Laukkarinen^1,2 (AUTHOR) johanna.laukkarinen@pshp.fi

Publikováno v: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p15726. 8p.

Plasma suPAR may help to distinguish between chronic pancreatitis and pancreatic cancer

Autor: Anssi Nikkola, Reetta Huttunen, Olli Limnell, Jussi Nikkola, Janne Aittoniemi, Juhani Sand, Irina Rinta-Kiikka, Johanna Laukkarinen, Anu Aronen, Isto Nordback

Publikováno v: Scandinavian journal of gastroenterology. 56(1)

Objectives SuPAR (soluble urokinase-type plasminogen activator receptor) is a biomarker reflecting the inflammatory state of the human body. Earlier studies suggest that urinary suPAR/creatinine ratio levels are elevated in chronic pancreatitis (CP),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5d5e56b1bd52c313f594374dc65cc6
https://pubmed.ncbi.nlm.nih.gov/33245246

Plasma level of soluble urokinase plasminogen activator receptor (suPAR) predicts long-term mortality after first acute alcohol-induced pancreatitis

Autor: Reetta Huttunen, Olli Limnell, Janne Aittoniemi, Anu Aronen, Anssi Nikkola, Juhani Sand, Johanna Laukkarinen, Jussi Nikkola, Isto Nordback

Background Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker associated with inflammatory and certain malignancies. Earlier we have shown that plasma suPAR (P-suPAR) predicts severity of acute alcohol-induced pancreatitis (AAP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976c1b8faf34797527d637160ab37a2a

Prevalence of Pancreatic Secretory Trypsin Inhibitor (SPINK1) gene mutation in patients with acute alcohol pancreatitis (AAP) compared to alcoholics and healthy controls

Autor: Pihla Paakkanen, Johanna Laukkarinen, Hanna Seppänen, Mika Kähönen, Anssi Nikkola, Olli T. Raitakari, Isto Nordback, Shivaprakash Jagalur Mutt, Ilkka Seppälä, Terho Lehtimäki, Juhani Sand, Karl-Heinz Herzig, Kari A. Mäkelä

Publikováno v: Pancreatology. 18:S36-S37

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94dea1a483c6924947b596dd3b3974bb
https://doi.org/10.1016/j.pan.2018.05.097

Plasma suPAR in differentiating malignant and benign pancreatic masses

Autor: Anu Aronen, Janne Aittoniemi, Reetta Huttunen, Anssi Nikkola, Jussi Nikkola, Olli Limnell, Juhani Sand, Johanna Laukkarinen

Publikováno v: Pancreatology. 19:S63

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de00a38b48c13b22f216cfd809cf1912
https://doi.org/10.1016/j.pan.2019.05.162