Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Anson V Hatch"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
Microfluidic barrier tissue models have emerged as advanced in vitro tools to explore interactions with external stimuli such as drug candidates, pathogens, or toxins. However, the procedures required to establish and maintain these systems can be ch
Externí odkaz:
https://doaj.org/article/1c66f59926cf4c2c91e66e91208954c9
Autor:
Balakrishnan Raja, Ronald F. Renzi, Tim Sherlock, Bi Hung Peng, Juan P. Olano, Anson V. Hatch, Steven Kemper, Carmen Pascente, David Shakarisaz, Paul Ruchhoeft, Katerina Kourentzi, Jennifer Knoop, Richard C. Willson
Publikováno v:
Lab on a Chip. 16:1625-1635
We present a microfluidic immunoassay platform based on the use of linear microretroreflectors embedded in a transparent polymer layer as an optical sensing surface, and micron-sized magnetic particles as light-blocking labels. Retroreflectors return
Autor:
Derek Dunford, Anup K. Singh, Mangesh I. Chaudhari, Christopher A. Baker, Anson V. Hatch, Ben Schudel, Kerrie Wu, Susan B. Rempe
Publikováno v:
ACS applied materialsinterfaces. 10(16)
The ability to observe lethal anthrax exotoxins translocating through size-constricting nanopores in vitro, combined with detailed sequence and structural data, has aided in elucidated mechanisms of exotoxin cell entry and toxicity. However, due to l
Autor:
Anson V. Hatch, Mathias Bækbo Andersen, Ali Mani, Benjamin Schudel, Susan B. Rempe, David M. Rogers, Junyu Mai
Publikováno v:
Langmuir. 30:7902-7912
We present a detailed analysis of the transient pH dynamics for a weak, buffered electrolyte subject to voltage-driven transport through an ion-selective membrane. We show that pH fronts emanate from the concentration polarization zone next to the me
Autor:
Vinay V. Abhyankar, Junyu Mai, Anson V. Hatch, Juan P. Olano, Richard C. Willson, Matthew E. Piccini
Publikováno v:
Biosensors and Bioelectronics. 54:435-441
We present advancements in microfluidic technology for rapid detection of as few as ten rickettsial organisms in complex biological samples. An immuno-reactive filter, macroporous polyacrylamide monolith (PAM), fabricated within a microfluidic channe
Publikováno v:
Journal of Virology
Rift Valley fever virus (RVFV) is an arbovirus within the Bunyaviridae family capable of causing serious morbidity and mortality in humans and livestock. To identify host factors involved in bunyavirus replication, we employed genome-wide RNA interfe
Autor:
Anson V. Hatch, Greg J. Sommer
Publikováno v:
ELECTROPHORESIS. 30:742-757
IEF is one of the most powerful and prevalent techniques used in separation sciences. The power of IEF comes from the fact that it not only separates analytes based on their pI but also focuses them into highly resolved bands. In line with the miniat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
Microfluidic barrier tissue models have emerged as advanced in vitro tools to explore interactions with external stimuli such as drug candidates, pathogens, or toxins. However, the procedures required to establish and maintain these systems can be ch
In the early stages of infection, patients develop non-specific or no symptoms at all. While waiting for identification of the infectious agent, precious window of opportunity for early intervention is lost. The standard diagnostics require affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7744a8b7cb5c1293a3915af683d0426c
https://doi.org/10.2172/1222536
https://doi.org/10.2172/1222536
Publikováno v:
Analytical Chemistry. 78:4976-4984
The potential of integration of functions in microfluidic chips is demonstrated by implementing on-chip preconcentration of proteins prior to on-chip protein sizing by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Two polymeri