Výsledky vyhledávání

A microsample collection device for electrostatically sorted cells or particles and its preparative use for biochemical analysis

Autor: William G. Hinson, Pipkin Jl, Anson Jf, Harry W. Tyrer, J. L. Hudson

Publikováno v: Cytometry. 2:390-394

Biochemical analysis of proteins extracted from mammalian cell nuclei which were sorted according to DNA content was greatly simplified using a special collection device to recover sorted nuclei. The device was developed for use with a sorting flow c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8899cab7757fee6226b58a7306ebc0
https://doi.org/10.1002/cyto.990020606

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Regulatory application of SAR/QSAR for priority setting of endocrine disruptors: A perspective

Autor: Weida Tong, Roger Perkins, Hong Fang, Anson Jf, Daniel M. Sheehan, Huixiao Hong, Qian Xie

Publikováno v: Pure and Applied Chemistry. 75:2375-2388

Some seven years have passed since the U.S. legislature mandated the Environmental Protection Agency (EPA) to develop and implement a screening and testing program for chemicals that may disrupt the delicate endocrine system. The envisioned EPA progr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b00235f18009d54f2c67adaf42601afc
https://doi.org/10.1351/pac200375112375

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Comparison of the cell cycle regulated synthesis and phosphorylation of stress proteins, actin isoforms and a novel actin-like protein following drug administration in cultured rat lymphocytes

Autor: Anane Aidoo, Lascelles E. Lyn-Cook, William G. Hinson, Anson Jf, Pipkin Jl, Ritchie J. Feuers, Daniel A. Casciano

Publikováno v: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 113:549-559

Administration of phytohemagglutinin initiated cycling of rat lymphocytes in vitro, and following treatment with this drug and other drugs in combination, lymphocytes were pulse labeled with [3H] leucine of [32P] phosphate. The nuclei were isolated f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c756631e4136db7858fc2c1c3341a91
https://doi.org/10.1016/0305-0491(95)02090-x

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The homology of a novel polypeptide with stress protein characteristics in embryonic mice brain and in the hypothalamus of caloric restricted rats as determined by ultramicro western blotting

Autor: William G. Hinson, Anson Jf, Ronald W. Hart, Lascelles E. Lyn-Cook, Daniel A. Casciano, Ritchie J. Feuers, James La Borde, Peter H. Duffy, Pipkin Jl

Publikováno v: Electrophoresis. 15:677-684

A novel protein (p34) was observed in polyacrylamide gel fluorographs of gestation day 13 embryonic mouse brain following retinoic acid dosing of dams. Another p34 polypeptide with identical gel migratory characteristics was seen in the hypothalamus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a2b7b793229e6832a6542c3595dee6
https://doi.org/10.1002/elps.1150150196

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Target tissue specificity of retinoic acid-induced stress proteins and malformations in mice

Autor: James B. LaBorde, William G. Hinson, Anson Jf, John F. Young, Deborah K. Hansen, Pipkin Jl, Daniel M. Sheehan

Publikováno v: Teratology. 44:19-28

Retinoic acid (RA) is teratogenic in rodents and also induces the synthesis of stress proteins in fetal mouse limb buds. To determine if the RA induction of stress proteins is target tissue specific, pregnant CD-1 mice were gavaged with 100 mg/kg RA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4f75432edabc5665e040ea938d62b3
https://doi.org/10.1002/tera.1420440105

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Retinoic acid-induced stress protein synthesis in the mouse

Autor: Daniel M. Sheehan, John F. Young, William G. Hinson, James B. LaBorde, Anson Jf, Pipkin Jl, Deborah K. Hansen

Publikováno v: Life sciences. 56(21)

We have previously demonstrated that stress proteins (SPs) are synthesized in tissues in which malformations are later observed following treatment with the developmental toxicant, retinoic acid (RA), on day 11 of gestation (GD 11). These proteins we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe6701e0fa440f04323f947d9b973d2
https://pubmed.ncbi.nlm.nih.gov/7739351

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Comparative studies of synthesis, phosphorylation, DNA binding and proteolytic characteristics of a novel protein during phases of the mouse spleen cell cycle

Autor: Ritchie J. Feuers, Henry M. Schol, Pipkin Jl, E. Robert Burns, Daniel A. Casciano, Daniel M. Sheehan, William G. Hinson, Anson Jf, Lascelles E. Lyn-Cook

Publikováno v: Comparative biochemistry and physiology. B, Comparative biochemistry. 104(2)

1. 1. Cultured mouse spleen cells were exposed to the mitogen Concanavalin A followed by isoproterenol, and nuclei were electronically sorted from seven partitions of the cell cycle. 2. 2. Several nuclear proteins, including stress proteins, which we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34029517a3b8a2c6e7f4521354a5ec9e
https://pubmed.ncbi.nlm.nih.gov/8462285

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Flow cytometric DNA analysis of corneal epithelium

Autor: Roberson Mc, Pipkin Jl, William G. Hinson, Anson Jf, Shock Jp, Burns Er, Brown Mf

Publikováno v: The American journal of anatomy. 187(3)

We have modified an existing technique in order to perform DNA analysi by flow cytometry (FCM) of corneal epithelium from the mouse, rat, chicken, rabbit, and human. This protocol permitted an investigation of human corneal scrapings from several cat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba29419a9f09dd51af539deb30544ae
https://pubmed.ncbi.nlm.nih.gov/2321558

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