Výsledky vyhledávání - "Anson C. K. Chan"

Akademický článek

Dissecting components of the Campylobacter jejuni fetMP-fetABCDEF gene cluster under iron limitation

Autor: Tomas Richardson-Sanchez, Anson C. K. Chan, Brendil Sabatino, Helen Lin, Erin C. Gaynor, Michael E. P. Murphy

Publikováno v: Microbiology Spectrum, Vol 12, Iss 1 (2024)

ABSTRACT Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. Acute infection can be an antecedent to highly debilitating long-term sequelae. The expression of iron acquisition systems is vital for C. jejuni to survive the

Externí odkaz: https://doaj.org/article/983e1be7015c46ff8f34e0d904fd628d

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Akademický článek

Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System

Autor: Martha M. Liu, Christine J. Boinett, Anson C. K. Chan, Julian Parkhill, Michael E. P. Murphy, Erin C. Gaynor

Publikováno v: mBio, Vol 9, Iss 4 (2018)

ABSTRACT Campylobacter jejuni is a pathogenic bacterium that causes gastroenteritis in humans yet is a widespread commensal in wild and domestic animals, particularly poultry. Using RNA sequencing, we assessed C. jejuni transcriptional responses to m

Externí odkaz: https://doaj.org/article/fd91b5ce7f24434ab035a653ed868d4b

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Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species

Autor: Robert G. Mothersole, Maxim Kolesnikov, Anson C. K. Chan, Emmanuella Oduro, Michael E. P. Murphy, Kirsten R. Wolthers

Publikováno v: Biochemistry. 61:1378-1391

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18bf79ac2f4c0da28b5c3cbb11508627
https://doi.org/10.1021/acs.biochem.2c00197

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A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly

Autor: Michael E. P. Murphy, Ivan Rajkovic, Anson C. K. Chan, Thomas M. Weiss, Tsutomu Matsui, Lucy Shapiro, Soichi Wakatsuki, Po-Nan Li, Jonathan Herrmann, Fatemeh Jabbarpour, John Smit

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Many microbes assemble a crystalline protein layer on their outer surface as an additional barrier and communication platform between the cell and its environment. Surface layer proteins efficiently crystallize to continuously coat the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d19230de1bb6fbaa2f454dbd3ba43a
https://doi.org/10.1073/pnas.1909798116

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Mechanism of the CBM35 domain in assisting catalysis by Ape1, a Campylobacter jejuni O-acetyl esterase

Autor: Anson C. K. Chan, Michael E. P. Murphy, Ian Y. Yen, Chang Sheng-Huei Lin

Peptidoglycan (PG) is O-acetylated by bacteria to resist killing by host lysozyme. During PG turnover, however, deacetylation is a prerequisite for glycan strand hydrolysis by lytic transglycosylases. Ape1, a de-O-acetylase from Campylobacter jejuni,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9724580d49506b7fedbb87022b76d0c0
https://doi.org/10.1101/2021.09.23.461501

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Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6

Autor: Michael E. P. Murphy, Stefan J. Haugen, Gregg T. Beckham, Lindsay D. Eltis, Rui Katahira, Anson C. K. Chan, Eugene Kuatsjah

Publikováno v: The Journal of Biological Chemistry

Lignostilbene-α,β-dioxygenases (LSDs) are iron-dependent oxygenases involved in the catabolism of lignin-derived stilbenes. Sphingobium sp. SYK-6 contains eight LSD homologs with undetermined physiological roles. To investigate which homologs are i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b43759759486fe9c487965b4216b6c
http://europepmc.org/articles/PMC8191317

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Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni

Autor: Martin E. Tanner, Jacob A. Brockerman, Chang Sheng-Huei Lin, Jean-Pierre Simorre, Erin C. Gaynor, Jenny Vermeulen, Lawrence P. McIntosh, Anson C. K. Chan, Arvind Soni, Michael E. P. Murphy

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
The Journal of Biological Chemistry

International audience; The helical morphology of Campylobacter jejuni, a bacterium involved in host gut colonization and pathogenesis in humans, is determined by the structure of the peptidoglycan (PG) layer. This structure is dictated by trimming o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0e0e23388d36bc0f74269c64db3c73
https://hal.science/hal-03328690

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A copper site is required for iron transport by the periplasmic proteins P19 and FetP

Autor: Michael E. P. Murphy, Dietrich H. Nies, Helen Lin, Gregor Grass, Anson C. K. Chan, Doreen Koch

Publikováno v: Metallomics : integrated biometal science. 12(10)

Campylobacter jejuni is a leading cause of food-borne gastrointestinal disease in humans and uropathogenic Escherichia coli is a leading cause of urinary tract infections. Both human pathogens harbour a homologous iron uptake system (termed cjFetM-P1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b3748a1cb9ab7ee258b74e82c2ee80
https://pubmed.ncbi.nlm.nih.gov/32780051

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