Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ansley M Nemeth"'
Autor:
Kenneth I. Onyedibe, Ansley M. Nemeth, Neetu Dayal, Richard D. Smith, Jones Lamptey, Robert K. Ernst, Roberta J. Melander, Christian Melander, Herman O. Sintim
Publikováno v:
ACS Infectious Diseases. 9:283-295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4350211a22995bb80c563fd8565afd4
https://doi.org/10.1021/acsinfecdis.2c00417
https://doi.org/10.1021/acsinfecdis.2c00417
Publikováno v:
Bioorganicmedicinal chemistry letters. 80
Gram-negative bacteria are intrinsically resistant to many classes of antibiotics, predominantly due to the impermeability of the outer membrane and the presence of efflux pumps. Small molecule adjuvants that circumvent these resistance mechanisms ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bd169b5ad6ae162739d4fa9b61ee63
https://pubmed.ncbi.nlm.nih.gov/36566797
https://pubmed.ncbi.nlm.nih.gov/36566797
Autor:
Kittipan Siwawannapong, Ansley M. Nemeth, Roberta J. Melander, Jie Rong, Jonathan R. Davis, Masahiko Taniguchi, Morgan E. Carpenter, Jonathan S. Lindsey, Christian Melander
Publikováno v:
ChemMedChem. 17
Multidrug resistant (MDR) bacteria are an increasing public health problem. One promising alternative to the development of new antibiotics is the use of antibiotic adjuvants, which would allow the continued use of FDA-approved antibiotics that have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adec02dbe2d6b2ef95f9a431a6336f9d
https://doi.org/10.1002/cmdc.202200286
https://doi.org/10.1002/cmdc.202200286
Autor:
Santiana A. Marrujo, Veronica B. Hubble, Jingdong Yang, Man Wang, Ansley M. Nemeth, Samantha L. Barlock, Dane Juarez, Richard D. Smith, Roberta J. Melander, Robert K. Ernst, Mayland Chang, Christian Melander
Publikováno v:
European Journal of Medicinal Chemistry. 253:115329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf5e85e9dd5ee84743ac37d1a82300e
https://doi.org/10.1016/j.ejmech.2023.115329
https://doi.org/10.1016/j.ejmech.2023.115329
Autor:
Roberta J. Melander, Anne E. Mattingly, Christian Melander, Veronica B Hubble, Kyle R Bartholomew, Sara M Brackett, Ansley M Nemeth, Alexander W. Weig, Samantha L. Barlock
Publikováno v:
ACS Medicinal Chemistry Letters. 11:1723-1731
Approximately 1.7 million Americans develop hospital associated infections each year, resulting in more than 98,000 deaths. One of the main contributors to such infections is the Gram-negative pathogen Acinetobacter baumannii. Recently, it was report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8620fe91c0eec6985feabd67ce1fa14f
https://doi.org/10.1021/acsmedchemlett.0c00276
https://doi.org/10.1021/acsmedchemlett.0c00276
Autor:
Veronica B, Hubble, Kyle R, Bartholomew, Alexander W, Weig, Sara M, Brackett, Samantha L, Barlock, Anne E, Mattingly, Ansley M, Nemeth, Roberta J, Melander, Christian, Melander
Publikováno v:
ACS Med Chem Lett
[Image: see text] Approximately 1.7 million Americans develop hospital associated infections each year, resulting in more than 98,000 deaths. One of the main contributors to such infections is the Gram-negative pathogen Acinetobacter baumannii. Recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a28e323964c37eea7f9d0c2e986bc34
https://pubmed.ncbi.nlm.nih.gov/32944140
https://pubmed.ncbi.nlm.nih.gov/32944140
Autor:
Christian Melander, Akash Basak, Tyler A. Hendricks, Leigh A. Jania, Patrick M. O'Connor, Santiana A. Marrujo, William T. Barker, Roberta J. Melander, Beverly H. Koller, Ansley M Nemeth, Ashley E. Sullivan, Alexander W. Weig
Publikováno v:
ChemMedChem
Infections caused by multi-drug resistant (MDR) bacteria, particularly Gram-negative bacteria, are an escalating global health threat. Often clinicians are forced to administer the last resort antibiotic colistin, however colistin resistance is becom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514bab61b6d0093a10fe6b352dc148ab
https://pubmed.ncbi.nlm.nih.gov/31756025
https://pubmed.ncbi.nlm.nih.gov/31756025
Autor:
Sara M Brackett, William T. Barker, Robert K. Ernst, Courtney E. Chandler, Ansley M Nemeth, Akash Basak, Beverly H. Koller, Christian Melander, Roberta J. Melander, William J. Zuercher, Leigh A. Jania
Publikováno v:
ACS Infect Dis
Kinase inhibitors comprise a diverse cohort of chemical scaffolds that are active in multiple biological systems. Currently, thousands of eukaryotic kinase inhibitors are commercially available, have well-characterized targets, and often carry pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d295f6b49242c0c0a1a0f946e8dfb2
https://pubmed.ncbi.nlm.nih.gov/31434474
https://pubmed.ncbi.nlm.nih.gov/31434474