Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ansis Maleckis"'
Autor:
Alons Lends, Asen Daskalov, Ansis Maleckis, Aline Delamare, Mélanie Berbon, Axelle Grélard, Estelle Morvan, Jayakrishna Shenoy, Antoine Dutour, James Tolchard, Abdelmajid Noubhani, Marie-France Giraud, Corinne Sanchez, Birgit Habenstein, Gilles Guichard, Guillaume Compain, Kristaps Jaudzems, Sven J. Saupe, Antoine Loquet
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
A method for cell-free synthesis of amyloid fibrils is reported that also allows for solid-state NMR analysis to characterize complex and pathological fibrillary assemblies.
Externí odkaz:
https://doaj.org/article/2425b18b9b474e05af291b67802899d9
Publikováno v:
Organic & Biomolecular Chemistry. 20:2424-2432
19F-NMR spectra of the protein GB1 produced by cell-free protein synthesis with fluorinated amino acids substituting their canonical parent amino acids show exceptionally large chemical shift dispersions, which indicate structural conservation.
Autor:
Bim Graham, Shereen Jabar, Gottfried Otting, Ansis Maleckis, Iresha D. Herath, Colum Breen, Lydia Topping, Henry W. Orton, Stephen J. Butler, Monika Szabo
Publikováno v:
Magnetic Resonance, Vol 3, Pp 1-13 (2022)
The metallo-β-lactamase IMP-1 features a flexible loop near the active site that assumes different conformations in single crystal structures, which may assist in substrate binding and enzymatic activity. To probe the position of this loop, we label
Site-selective generation of lanthanoid binding sites on proteins using 4-fluoro-2,6-dicyanopyridine
Autor:
Sreelakshmi Mekkattu Tharayil, Mithun C. Mahawaththa, Akiva Feintuch, Ansis Maleckis, Sven Ullrich, Richard Morewood, Michael J. Maxwell, Thomas Huber, Christoph Nitsche, Daniella Goldfarb, Gottfried Otting
The paramagnetism of a lanthanoid tag site-specifically installed on a protein provides a rich source of structural information accessible by nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) spectroscopy. Here we report a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc30d1da696e42187a03bfa2a9dce7d2
https://mr.copernicus.org/articles/3/169/2022/
https://mr.copernicus.org/articles/3/169/2022/
Autor:
Sreelakshmi Mekkattu Tharayil, Mithun C. Mahawaththa, Akiva Feintuch, Ansis Maleckis, Sven Ullrich, Richard Morewood, Thomas Huber, Christoph Nitsche, Daniella Goldfarb, Gottfried Otting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f197b06959796ad7f203cd58b8a7f787
https://doi.org/10.5194/mr-2022-11-supplement
https://doi.org/10.5194/mr-2022-11-supplement
Publikováno v:
Organic & Biomolecular Chemistry. 19:5133-5147
Synthesis of indoles labeled with 13C–1H and 13C–19F spin pairs is described. All syntheses utilize inexpensive carbon–13C dioxide as the 13C isotope source. Ruthenium-mediated ring-closing metathesis is the key step in construction of the 13C
Autor:
Henry W. Orton, Iresha D. Herath, Ansis Maleckis, Shereen Jabar, Monika Szabo, Bim Graham, Colum Breen, Lydia Topping, Stephen J. Butler, Gottfried Otting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b98338e7fc0b6f29de6b24b95d63695
https://doi.org/10.5194/mr-2021-63-supplement
https://doi.org/10.5194/mr-2021-63-supplement
Publikováno v:
Organicbiomolecular chemistry. 19(23)
Synthesis of indoles labeled with 13C-1H and 13C-19F spin pairs is described. All syntheses utilize inexpensive carbon-13C dioxide as the 13C isotope source. Ruthenium-mediated ring-closing metathesis is the key step in construction of the 13C contai
Autor:
Iresha D. Herath, Yi Jiun Tan, Daniella Goldfarb, Thomas Huber, Adarshi P. Welegedara, Angeliki Giannoulis, Mithun C. Mahawaththa, Gottfried Otting, Ansis Maleckis, Ruchira Bandara
Publikováno v:
Chembiochem : a European journal of chemical biology. 22(8)
The selenol group of selenocysteine is much more nucleophilic than the thiol group of cysteine. Selenocysteine residues in proteins thus offer reactive points for rapid post-translational modification. Herein, we show that selenoproteins can be expre
Autor:
Ansis Maleckis, Melanie S. Sanford
Publikováno v:
Organometallics. 33:3831-3839
The synthesis and characterization of a series of fluoroalkyl palladium(II) and nickel(II) complexes via decarbonylation of the corresponding acylmetal species is reported. At palladium(II), labile supporting ligands such as tri-o-tolylphosphine are