Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anshu P. Gounder"'
Autor:
Kathryn W. Juchem, Anshu P. Gounder, Jian Ping Gao, Elise Seccareccia, Narayana Yeddula, Nicholas J. Huffmaster, Alexandra Côté-Martin, Steven E. Fogal, Donald Souza, Sarah Sirui Wang, Elizabeth R. A. Glynn, Ivy Yung, Julie Ritchie, Li Li, Jie Zheng, M. Lamine Mbow, Jun Li, Sumit K. Chanda
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
NFAT activating protein with ITAM motif 1 (NFAM1) is an ITAM bearing-transmembrane receptor that has been reported to play a role in B cell signaling and development. We performed expression analysis of NFAM1 using publicly available gene expression
Externí odkaz:
https://doaj.org/article/2f3f4e6c77ec4d86beb354c5637d3437
Autor:
Jian-Ping Yang, Rachel Toughiri, Anshu P Gounder, Dan Scheibe, Matt Petrus, Sarah J Fink, Sebastien Vallee, Jon Kenniston, Nikolaos Papaioannou, Steve Langston, Narender R Gavva, Shane R Horman
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0307049 (2024)
Induction of fetal hemoglobin (HbF) has been shown to be a viable therapeutic approach to treating sickle cell disease and potentially other β-hemoglobinopathies. To identify targets and target-modulating small molecules that enhance HbF expression,
Externí odkaz:
https://doaj.org/article/8f230a19fa88408da5af340d0b8fa670
Autor:
Anshu P Gounder, Christine C Yokoyama, Nicholas N Jarjour, Traci L Bricker, Brian T Edelson, Adrianus C M Boon
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007001 (2018)
Pro-inflammatory cytokinemia is a hallmark of highly pathogenic H5N1 influenza virus (IAV) disease yet little is known about the role of host proteins in modulating a pathogenic innate immune response. The host Interferon Induced Protein 35 (Ifi35) h
Externí odkaz:
https://doaj.org/article/fbf7620cce494db7af4bb838d1c65d9c
Autor:
Sarah S Wilson, Beth A Bromme, Mayumi K Holly, Mayim E Wiens, Anshu P Gounder, Youngmee Sul, Jason G Smith
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006446 (2017)
The small intestinal epithelium produces numerous antimicrobial peptides and proteins, including abundant enteric α-defensins. Although they most commonly function as potent antivirals in cell culture, enteric α-defensins have also been shown to en
Externí odkaz:
https://doaj.org/article/fd2216afedea466ca68a6bbfd4d8888b
Autor:
Michael Lagunoff, Daniel J. Vogt, Jason G. Smith, Shivam A. Zaver, Terri A. DiMaio, Anshu P. Gounder, Alice Ranjan
Publikováno v:
Virology
During DNA virus infections, detection of cytosolic DNA by the cGAS-STING pathway leads to activation of IFN-β. Kaposi’s Sarcoma Herpesvirus (KSHV), an oncogenic DNA virus, is the etiological agent of Kaposi’s Sarcoma, an endothelial cell (EC)-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6d8e2829021e473e650d7ca12a47fb
https://doi.org/10.1016/j.virol.2019.11.012
https://doi.org/10.1016/j.virol.2019.11.012
Autor:
Anshu P. Gounder, Adrianus C. M. Boon
Publikováno v:
The Journal of Immunology. 202:341-350
Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject of intense research and many molecular determinan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1378843d97c02cd75621cfd2b31c83
https://doi.org/10.4049/jimmunol.1801010
https://doi.org/10.4049/jimmunol.1801010
Autor:
Christopher Churas, Lisa Miorin, Dexter Pratt, Anshu P. Gounder, Aaron L. Oom, Laura Martin-Sancho, Sumit K. Chanda, Judd F. Hultquist, Sophie Liu, Courtney Nguyen, Max W. Chang, Ariel Rodriguez-Frandsen, Trey Ideker, Alan M. O’Neill, Matthew Urbanowski, Yuan Pu, Megan L. Shaw, Sara Brin Rosenthal, John C. Guatelli, Paul D. De Jesus, Charlotte A. Stoneham, Christopher Benner, Mary K. Lewinski, Matthew B. Frieman, Lars Pache, Adolfo García-Sastre, Xin Yin
Publikováno v:
bioRxiv
A deficient interferon response to SARS-CoV-2 infection has been implicated as a determinant of severe COVID-19. To identify the molecular effectors that govern interferon control of SARS-CoV-2 infection, we conducted a large-scale gain-of-function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdb27efac76461cbaf3aeed7ee78337
https://europepmc.org/articles/PMC7536870/
https://europepmc.org/articles/PMC7536870/
Autor:
Nicolle D. Myers, Jason G. Smith, Ciara T. Hu, Beth A. Bromme, Youngmee Sul, Karina Diaz, Ksenia V. Skorohodova, Anshu P. Gounder
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 11, p e1009018 (2020)
PLoS Pathogens, Vol 16, Iss 11, p e1009018 (2020)
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb7f53f7d37743b61c863cdb80d2db3
Autor:
Sharmila Nair, Vicky Lampropoulou, Ekaterina Esaulova, Anshu P. Gounder, Maxim N. Artyomov, Adrianus C. M. Boon, Michael S. Diamond, Elizabeth A. Schwarzkopf, Ekaterina Loginicheva, Tara R. Bradstreet, Brian T. Edelson, Jeremy P. Huynh, Christina L. Stallings
Publikováno v:
The Journal of Experimental Medicine
Nair et al. define a key role for Irg1 in minimizing the pathological immune response associated with Mtb infection. Using Irg1−/− and Irg1fl/fl conditional mice, detailed immune cell analysis, and transcriptional profiling, their data supports a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b7b64bf1bf436ce79642fedccf62bd
http://europepmc.org/articles/PMC5881474
http://europepmc.org/articles/PMC5881474
Autor:
Trey Ideker, Megan L. Shaw, Sara Brin Rosenthal, Matthew Urbanowski, Sumit K. Chanda, Chunxiang Wu, Thomas J. Hope, Yong Xiong, Charlotte A. Stoneham, Matthew B. Frieman, Aaron L. Oom, John C. Guatelli, Dexter Pratt, Sophie Liu, Christopher Churas, Courtney Nguyen, Anshu P. Gounder, Mary K. Lewinski, Lisa Miorin, Adolfo García-Sastre, Mark E. Becker, Stuart Weston, Yuan Pu, Alan M. O’Neill, Max W. Chang, Laura Martin-Sancho, Christopher Benner, Fan Zheng, Heather M. Curry, Paul D. De Jesus, Judd F. Hultquist, Ariel Rodriguez-Frandsen, Xin Yin, Lars Pache
Publikováno v:
Molecular cell, vol 81, iss 12
Molecular Cell
Molecular Cell
A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus disease 2019 (COVID-19). To identify the molecular effectors that govern IFN co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb9bcf12fce94be23d569fee1692ee0
https://doi.org/10.1016/j.molcel.2021.04.008
https://doi.org/10.1016/j.molcel.2021.04.008