Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ansgar Petersen"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Biophysical cues have the ability to enhance cellular signaling response to Bone Morphogenetic Proteins, an essential growth factor during bone development and regeneration. Yet, therapeutic application of Bone Morphogenetic Protein 2 (BMP2)
Externí odkaz:
https://doaj.org/article/ad074a2787c9465e8f9f6a4cd5f71794
Autor:
Julia Mehl, Saeed Khomeijani Farahani, Erik Brauer, Alexandra Klaus‐Bergmann, Tobias Thiele, Agnes Ellinghaus, Eireen Bartels‐Klein, Katharina Koch, Katharina Schmidt‐Bleek, Ansgar Petersen, Holger Gerhardt, Viola Vogel, Georg N. Duda
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Bone fracture healing is regulated by mechanobiological cues. Both, extracellular matrix (ECM) deposition and microvascular assembly determine the dynamics of the regenerative processes. Mechanical instability as by inter‐fragmentary shear
Externí odkaz:
https://doaj.org/article/2bcadc7c650844098b756206036103db
Autor:
Kathleen Pappritz, Sarah-Lena Puhl, Isabel Matz, Erik Brauer, Yi Xuan Shia, Muhammad El-Shafeey, Suzanne E. Koch, Kapka Miteva, Christin Mucha, Georg N. Duda, Ansgar Petersen, Sabine Steffens, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAge and sex are prominent risk factors for heart failure and determinants of structural and functional changes of the heart. Cardiac fibroblasts (cFB) are beyond their task as extracellular matrix-producing cells further recognized as infla
Externí odkaz:
https://doaj.org/article/431c58d3a3d04068a86c2900a66337bc
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The success of cell-free in situ tissue engineering approaches depends on an appropriate recruitment of autologous cells from neighboring tissues. This identifies cellular migration as a critical parameter for the pre-clinical characterization of bio
Externí odkaz:
https://doaj.org/article/2347c357f4d0410185a6157220545c30
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Current clinical treatments of osteochondral defects in articulating joints are frequently not successful in restoring articular surfaces. Novel scaffold-based tissue engineering strategies may help to improve current treatment options and foster a t
Externí odkaz:
https://doaj.org/article/9781038c15af45c28eeecd9c6088e500
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Osteochondral defects in joints require surgical intervention to relieve pain and restore function. However, no current treatment enables a complete reconstitution of the articular surface. It is known that both mechanical and biological factors play
Externí odkaz:
https://doaj.org/article/0818e687a66e46978275c4eb5e3196a4
Collagen Fibrils Mechanically Contribute to Tissue Contraction in an In Vitro Wound Healing Scenario
Autor:
Erik Brauer, Evi Lippens, Oliver Klein, Grit Nebrich, Sophie Schreivogel, Gabriela Korus, Georg N. Duda, Ansgar Petersen
Publikováno v:
Advanced Science, Vol 6, Iss 9, Pp n/a-n/a (2019)
Abstract Wound contraction is an ancient survival mechanism of vertebrates that results from tensile forces supporting wound closure. So far, tissue tension was attributed to cellular forces produced by tissue‐resident (myo‐)fibroblasts alone. Ho
Externí odkaz:
https://doaj.org/article/58706d6932654f2a9fac22842ffdde45
Autor:
Thaqif El Khassawna, Alessandro Serra, Christian H. Bucher, Ansgar Petersen, Claudia Schlundt, Ireen Könnecke, Deeksha Malhan, Sebastian Wendler, Hanna Schell, Hans-Dieter Volk, Katharina Schmidt-Bleek, Georg N. Duda
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Bone is a unique organ able to regenerate itself after injuries. This regeneration requires the local interplay between different biological systems such as inflammation and matrix formation. Structural reconstitution is initiated by an inflammatory
Externí odkaz:
https://doaj.org/article/ae3344d6371340768eebe63e1c8034d9
Autor:
Pascal Joly, Georg N Duda, Martin Schöne, Petra B Welzel, Uwe Freudenberg, Carsten Werner, Ansgar Petersen
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73545 (2013)
To heal tissue defects, cells have to bridge gaps and generate new extracellular matrix (ECM). Macroporous scaffolds are frequently used to support the process of defect filling and thus foster tissue regeneration. Such biomaterials contain micro-voi
Externí odkaz:
https://doaj.org/article/0f1ef727dc1e442fb4dba450f724a677
Autor:
Georg N. Duda, Sven Geissler, Sara Checa, Serafeim Tsitsilonis, Ansgar Petersen, Katharina Schmidt-Bleek
Publikováno v:
Nature Reviews Rheumatology. 19:78-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce216de5ba67312b5cce4afb6853aefd
https://doi.org/10.1038/s41584-022-00887-0
https://doi.org/10.1038/s41584-022-00887-0