Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anselm F. L. Schneider"'
Publikováno v:
Angewandte Chemie. 133:22246-22252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cce1805e5d87be0044b95d1bdf4c6ce
https://doi.org/10.1002/ange.202103068
https://doi.org/10.1002/ange.202103068
Autor:
Samuel Hintermann, Andreas Marzinzik, Johannes Ottl, Joerg Kallen, Therese-Marie Stachyra, Patrick C. Reid, Stephan Ruetz, Anselm F. L. Schneider, Christian P. R. Hackenberger, Christoph E. Dumelin, Sebastien Ripoche
Publikováno v:
RSC Chemical Biology
Mouse double minute 2 homolog (MDM2, Hdm2) is an important negative regulator of the tumor suppressor p53. Using a mRNA based display technique to screen a library of >1012in vitro-translated cyclic peptides, we have identified a macrocyclic ligand t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79c0089311703a726113d94f5b84104
http://europepmc.org/articles/PMC8637822
http://europepmc.org/articles/PMC8637822
Autor:
Marina Kithil, Martin Lehmann, Christian P. R. Hackenberger, M. Cristina Cardoso, Anselm F. L. Schneider
Publikováno v:
Nature Chemistry. 13:530-539
Enabling the cellular delivery and cytosolic bioavailability of functional proteins constitutes a major challenge for the life sciences. Here we demonstrate that thiol-reactive arginine-rich peptide additives can enhance the cellular uptake of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d3b51bcdcb4f049fd7748653ee531b
https://doi.org/10.1038/s41557-021-00661-x
https://doi.org/10.1038/s41557-021-00661-x
Autor:
Marcus Gerlach, Anselm F. L. Schneider, Dominik Schumacher, Marc-André Kasper, Jonas Helma, Christian P. R. Hackenberger, Stefanie Boldt, Heinrich Leonhardt, Mathias Christmann, Philipp Ochtrop, Christiane Groneberg
Publikováno v:
Chembiochem
Herein, the application of N‐hydroxysuccinimide‐modified phosphonamidate building blocks for the incorporation of cysteine‐selective ethynylphosphonamidates into lysine residues of proteins, followed by thiol addition with small molecules and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dfa7c81315bdd6ecb44f243d35d28a
https://doi.org/10.1002/cbic.201900587
https://doi.org/10.1002/cbic.201900587
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2355
Proteins conjugated to cyclic cell-penetrating peptides (cCPPs) haAbstractve been shown to be effectively taken up by living cells. Conjugation of proteins to cCPPs in a cleavable manner leads to localization in the cytosol and immediate bioavailabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d30603e33883452158f5d9a2ce63912
https://pubmed.ncbi.nlm.nih.gov/34386966
https://pubmed.ncbi.nlm.nih.gov/34386966
Publikováno v:
Bioconjugate Chemistry. 30:400-404
The delivery of entire functional proteins into living cells is a long-sought goal in science. Cyclic cell-penetrating peptides (cCPPs) have proven themselves to be potent delivery vehicles to carry proteins upon conjugation into the cytosol of livin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9bc5901f672d7fd90dabd1fa7e1424
https://doi.org/10.1021/acs.bioconjchem.8b00855
https://doi.org/10.1021/acs.bioconjchem.8b00855
Publikováno v:
Methods in Molecular Biology ISBN: 9781071616161
Proteins conjugated to cyclic cell-penetrating peptides (cCPPs) haAbstractve been shown to be effectively taken up by living cells. Conjugation of proteins to cCPPs in a cleavable manner leads to localization in the cytosol and immediate bioavailabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d47f817e6ca9a0c63c0fd4e1857ee76
https://doi.org/10.1007/978-1-0716-1617-8_22
https://doi.org/10.1007/978-1-0716-1617-8_22
Cell-Permeable Nanobodies Allow Dual-Color Super-Resolution Microscopy in Untransfected Living Cells
Publikováno v:
Angewandte Chemie (International Ed. in English)
Super‐resolution microscopy in living cells can be restricted by the availability of small molecule probes, which only exist against few targets and genetically encoded tags. Here, we expand the applicability of live‐cell STED by engineering cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c071fc6318ad7426c177748e61ab8b
https://doi.org/10.17169/refubium-32185
https://doi.org/10.17169/refubium-32185
Autor:
Heinrich Leonhardt, Christian P. R. Hackenberger, Jonas Helma, Anselm F. L. Schneider, Dominik Schumacher
Publikováno v:
Angewandte Chemie (International Ed. in English)
Nanobodies can be seen as next‐generation tools for the recognition and modulation of antigens that are inaccessible to conventional antibodies. Due to their compact structure and high stability, nanobodies see frequent usage in basic research, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29a9772a82bcc6f227f2bd9896f8369
https://doi.org/10.1002/anie.201708459
https://doi.org/10.1002/anie.201708459
Autor:
Anselm F. L. Schneider, Heinrich Leonhardt, Christian P. R. Hackenberger, Jonas Helma, Dominik Schumacher
Publikováno v:
Angewandte Chemie. 130:2336-2357
Nanobodies can be considered as next-generation life science tools for the recognition and modulation of antigens that are inaccessible to conventional antibodies. Due to their compact structure and high stability, nanobodies see frequent usage in ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da372e19045249a564e196297ad2494a
https://doi.org/10.1002/ange.201708459
https://doi.org/10.1002/ange.201708459