Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ansari Mukhtar Aleem"'
Publikováno v:
Clinical Epigenetics, Vol 4, Iss 1, p 23 (2012)
Abstract Background The putative regulatory role of the male reproductive hormones in the molecular mechanism underlying chromatin condensation remains poorly understood. In the past decade, we developed two adult male rat models wherein functional d
Externí odkaz:
https://doaj.org/article/4de8620ded24499ba2b4936c6739c3ea
Autor:
Mohammed Sami Alhaddad, Abdullah F. Al-Naim, Bayan Jamal AlMulhim, Ansari Mukhtar Aleem, Malak J. Alali, Iheb Mohamed Bougmiza, Abdullatif Sami Al Rashed, Abdulaziz I. Al-Thafar, Saima Kashif
Publikováno v:
Neurology, Psychiatry and Brain Research. 31:32-36
Objective This study investigates the prevalence of depression and its predictors among the general population in Al-Ahsa, a city in the Eastern Province of the Kingdom of Saudi Arabia. Methods A cross-sectional study was conducted from June 2015 to
Autor:
Anthony T. Iavarone, Theodore R. Holman, Adam R. Offenbacher, Wilian A. Cortopassi, Chris Whittington, Wan-Chen Tsai, Ansari Mukhtar Aleem, Chakrapani Kalyanaraman, Ewa Skrzypczak-Jankun, Angel Baroz, Matthew P. Jacobson
Publikováno v:
Biochemistry. 60(10)
It was previously shown that human platelet 12S-lipoxygenase (h12-LOX) exists as a dimer; however, the specific structure is unknown. In this study, we create a model of the dimer through a combination of computational methods, experimental mutagenes
Autor:
Theodore R. Holman, Melinee D’silva, Harman S. Brah, Wan-Chen Tsai, Jennyfer Tena, Ansari Mukhtar Aleem, Chakrapani Kalyanaraman, Mirella Rivera-Velazquez, Sarvind Tripathi, Matthew P. Jacobson, Jerry L. Nadler
Publikováno v:
Bioorganic & Medicinal Chemistry. 46:116347
Human platelet 12-(S)-Lipoxygenase (12-LOX) is a fatty acid metabolizing oxygenase that plays an important role in platelet activation and cardiometabolic disease. ML355 is a specific 12-LOX inhibitor that has been shown to decrease thrombosis withou
Autor:
Marimar Hernandez-Perez, Kimberly El, Ganesha Rai, Sarah A. Tersey, Cody A. Sorrell, Raghavendra G. Mirmira, Ansari Mukhtar Aleem, Abhishek Kulkarni, Theodore R. Holman, Isra Haider, Ryan M. Anderson, Niharika Samala
Publikováno v:
FASEB J
12-Lipoxygenase (12-LOX) is a key enzyme in arachidonic acid metabolism, and alongside its major product, 12-HETE, plays a key role in promoting inflammatory signaling during diabetes pathogenesis. Although 12-LOX is a proposed therapeutic target to
Autor:
Theodore R. Holman, Chakrapani Kalyanaraman, Jennyfer Tena, Matthew P. Jacobson, Gabriella Alvarez, Wan-Chen Tsai, Ansari Mukhtar Aleem, Joshua D. Deschamps
Publikováno v:
Biochemistry
Biochemistry, vol 58, iss 6
Biochemistry, vol 58, iss 6
Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f546fac581c1f96f8ac1a03aa67ffd
https://europepmc.org/articles/PMC7270147/
https://europepmc.org/articles/PMC7270147/
Autor:
Mansour Abdullah Al Naim, Kaberi Feroze Kaliyadan, Abdullatif Sami Al Rashed, Khalid Abdullah Al Shehab, Hisham Sameer Al Hathloul, Hamad Abdulaziz Al Subaie, Ansari Mukhtar Aleem
Publikováno v:
Nigerian Journal of Ophthalmology; Vol 23, No 1 (2015); 12-15
Objective: The objective was to assess the profile of different types of glaucoma in a University Health Centre in Al‑Ahsa, Saudi Arabia.Materials and Methods: It is a retrospective study in which the files of the patients at King Faisal University
Autor:
Abdullah F. Al-Naim, Ansari Mukhtar Aleem, Khalid Saleh Al-Mulhim, Abdulaziz Ahmed Al-Darwish, Mohammed Saad Morsi, Nasser Khaled Al-Otaibi
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 15(6)
Background Cervical cancer is the second most common cancer among females and also the most preventable. In the literature there is abundant evidence that awareness regarding cervical cancer and its prevention is low in the developing countries. Medi