Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ans M M van Pelt"'
Autor:
Robert B Struijk, Lambert C J Dorssers, Peter Henneman, Martin A Rijlaarsdam, Andrea Venema, Aldo Jongejan, Marcel M A M Mannens, Leendert H J Looijenga, Sjoerd Repping, Ans M M van Pelt
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230253 (2020)
Autologous transplantation of spermatogonial stem cells is a promising new avenue to restore fertility in infertile recipients. Expansion of the initial spermatogonial stem cell pool through cell culturing is a necessary step to obtain enough cells f
Externí odkaz:
https://doaj.org/article/1c2e7d3a5bd04db78c169ad269fd23fe
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract In principle, germline cells possess the capability to transmit a nearly unaltered set of genetic material to infinite future generations, whereas somatic cells are limited by strict growth constraints necessary to assure an organism’s phy
Externí odkaz:
https://doaj.org/article/fee5ef7725da4c08941c4e5827747a30
Autor:
Ewart W Kuijk, Jeffrey de Gier, Susana M Chuva de Sousa Lopes, Ian Chambers, Ans M M van Pelt, Ben Colenbrander, Bernard A J Roelen
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10987 (2010)
NANOG is a key player in pluripotency and its expression is restricted to pluripotent cells of the inner cell mass, the epiblast and to primordial germ cells. Spermatogenesis is closely associated with pluripotency, because through this process highl
Externí odkaz:
https://doaj.org/article/bf2b995601c643e592957276c173c077
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: Autologous transplantation of spermatogonial stem cells (SSCs) isolated from cryopreserved testicular biopsies obtained before oncological treatment could restore fertility in male childhood cancer survivors. There is a clear necessity
Externí odkaz:
https://doaj.org/article/6fe61839132f4fcdb5eae247c07fd5a2
Autor:
Joana B. Serrano, Nils C. Tabeling, Cindy M. de Winter-Korver, Saskia K. M. van Daalen, Ans M. M. van Pelt, Callista L. Mulder
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Spermatogonial stem cell transplantation (SSCT) is proposed as a fertility therapy for childhood cancer survivors. SSCT starts with cryopreserving a testicular biopsy prior to gonadotoxic treatments such as cancer treatments. When
Externí odkaz:
https://doaj.org/article/1abbe68efe0342e8bab574dc8981b903
Autor:
Mariska A M Schröder, Fred C G J Sweep, Antonius E van Herwaarden, Rod T Mitchell, Jitske Eliveld, Ans M M van Pelt, Alan E Rowan, Darren Korbie, Nike M M L Stikkelbroeck, Hedi L Claahsen-van der Grinten, Paul N Span
Publikováno v:
European Journal of Endocrinology, 187, 607-615
European Journal of Endocrinology, 187(5), 607-615. BioScientifica Ltd.
European Journal of Endocrinology, 187, 5, pp. 607-615
Schröder, M A M, Sweep, F C G J, Van Herwaarden, A E, Mitchell, R T, Eliveld, J, Van Pelt, A M M, Rowan, A E, Korbie, D, Stikkelbroeck, N M M L, Claahsen-van Der Grinten, H L & Span, P N 2022, ' Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues ', European Journal of Endocrinology . https://doi.org/10.1530/EJE-22-0143
European Journal of Endocrinology, 187(5), 607-615. BioScientifica Ltd.
European Journal of Endocrinology, 187, 5, pp. 607-615
Schröder, M A M, Sweep, F C G J, Van Herwaarden, A E, Mitchell, R T, Eliveld, J, Van Pelt, A M M, Rowan, A E, Korbie, D, Stikkelbroeck, N M M L, Claahsen-van Der Grinten, H L & Span, P N 2022, ' Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues ', European Journal of Endocrinology . https://doi.org/10.1530/EJE-22-0143
Background Testicular adrenal rest tumors (TART) are a common complication of unknown cellular origin in patients with congenital adrenal hyperplasia (CAH). These benign tumors have both adrenal and testicular characteristics and are hypothesized to
Autor:
Ieva Masliukaite, Elissavet Ntemou, Elizabeth A M Feijen, Marianne van de Wetering, Andreas Meissner, Alexandre T Soufan, Sjoerd Repping, Leontien M C Kremer, Kirsi Jahnukainen, Ellen Goossens, Ans M M van Pelt
Publikováno v:
Human reproduction (Oxford, England), 38(3), 359-370. Oxford University Press
Masliukaite, I, Ntemou, E, Feijen, E A M, van de Wetering, M, Meissner, A, Soufan, A T, Repping, S, Kremer, L M C, Jahnukainen, K, Goossens, E & van Pelt, A M M 2023, ' Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis : a retrospective study of a male fertility preservation cohort ', Human reproduction (Oxford, England), vol. 38, no. 3, pp. 359-370 . https://doi.org/10.1093/humrep/dead004
Masliukaite, I, Ntemou, E, Feijen, E A M, van de Wetering, M, Meissner, A, Soufan, A T, Repping, S, Kremer, L M C, Jahnukainen, K, Goossens, E & van Pelt, A M M 2023, ' Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis : a retrospective study of a male fertility preservation cohort ', Human reproduction (Oxford, England), vol. 38, no. 3, pp. 359-370 . https://doi.org/10.1093/humrep/dead004
STUDY QUESTIONWhat is the impact of cancer or hematological disorders on germ cells in pediatric male patients?SUMMARY ANSWERSpermatogonial quantity is reduced in testes of prepubertal boys diagnosed with cancer or severe hematological disorder compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb8670db0d7a2441c926d09fbb131df
http://hdl.handle.net/10138/355944
http://hdl.handle.net/10138/355944
Publikováno v:
Tijdschrift voor Urologie. 12:65-70
Among many deleterious ramifications of oncological treatments, there is permanent male infertility due to the damage to spermatogonial stem cells (SSC) in the testes after chemotherapy or irradiation. For those patients that cannot produce sperm bef
Autor:
Letizia De Chiara, Elvira Smeralda Famulari, Sharmila Fagoonee, Saskia K. M. van Daalen, Stefano Buttiglieri, Alberto Revelli, Emanuela Tolosano, Lorenzo Silengo, Ans M. M. van Pelt, Fiorella Altruda
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Mesenchymal stem cells hold great promise for regenerative medicine as they can be easily isolated from different sources such as adipose tissue, bone marrow, and umbilical cord blood. Spontaneously arising pluripotent stem cells can be obtained in c
Externí odkaz:
https://doaj.org/article/659415803a0e4fbf994885f43924c753
Autor:
Iris Sanou, Jillis van Maaren, Jitske Eliveld, Qijing Lei, Andreas Meißner, Annemieke A. de Melker, Geert Hamer, Ans M. M. van Pelt, Callista L. Mulder
Publikováno v:
Sanou, I, van Maaren, J, Eliveld, J, Lei, Q, Meißner, A, de Melker, A A, Hamer, G, van Pelt, A M M & Mulder, C L 2022, ' Spermatogonial Stem Cell-Based Therapies : Taking Preclinical Research to the Next Level ', Frontiers in Endocrinology, vol. 13, 850219 . https://doi.org/10.3389/fendo.2022.850219
Fertility preservation via biobanking of testicular tissue retrieved from testicular biopsies is now generally recommended for boys who need to undergo gonadotoxic treatment prior to the onset of puberty, as a source of spermatogonial stem cells (SSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba077a20397e94e20611d169b64c8174
https://research.vumc.nl/en/publications/e62bba22-0a5a-4980-92e7-e5e2f5b1c7e6
https://research.vumc.nl/en/publications/e62bba22-0a5a-4980-92e7-e5e2f5b1c7e6