Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Ans, Punt"'
Autor:
Lorenzo Pedroni, Jochem Louisse, Ans Punt, Jean Lou C. M. Dorne, Chiara Dall’Asta, Luca Dellafiora
Publikováno v:
Toxins, Vol 15, Iss 2, p 94 (2023)
Safrole, a 162.2 Da natural compound belonging to the alkenylbenzenes class, is classified as a possible carcinogen to humans by IARC (group IIB) and has proven to be genotoxic and carcinogenic to rodents. Despite its use as a food or feed additive,
Externí odkaz:
https://doaj.org/article/ebf0a3bb97974406a935bad225008780
Autor:
Sylvia Notenboom, Ans Punt, Rudolf Hoogenveen, Marco J. Zeilmaker, Ron L. A. P. Hoogenboom, Bas G. H. Bokkers
Publikováno v:
Food Additives and Contaminants-Part A 40 (2023) 1
Food Additives and Contaminants-Part A, 40(1), 96-109
Food Additives and Contaminants-Part A, 40(1), 96-109
Calibration of a kinetic model for the transfer of PCDD/Fs and dl-PCBs from feed to the hen's body and eggs was thus far restricted to the total TEQ concentration, i.e. the summed concentrations of PCDD/Fs and dl-PCBs expressed in terms of equivalent
Autor:
Jochem Louisse, Luca Dellafiora, Jeroen J. M. W. van den Heuvel, Deborah Rijkers, Liz Leenders, Jean-Lou C. M. Dorne, Ans Punt, Frans G. M. Russel, Jan B. Koenderink
Publikováno v:
Archives of Toxicology, 97, 3, pp. 685-696
Archives of Toxicology 97 (2023) 3
Archives of Toxicology, 97(3), 685-696
Archives of Toxicology, 97, 685-696
Archives of Toxicology 97 (2023) 3
Archives of Toxicology, 97(3), 685-696
Archives of Toxicology, 97, 685-696
Contains fulltext : 291310.pdf (Publisher’s version ) (Open Access) Poly- and perfluoroalkyl substances (PFASs) are omnipresent in the environment and have been shown to accumulate in humans. Most PFASs are not biotransformed in animals and humans,
Autor:
Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, Richard Helsdingen, Sjef Boeren, Jacques J. M. Vervoort, Ivonne M. C. M. Rietjens, Hans Bouwmeester
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Upon ingestion, nanoparticles can interact with the intestinal epithelial barrier potentially resulting in systemic uptake of nanoparticles. Nanoparticle properties have been described to influence the protein corona formation and
Externí odkaz:
https://doaj.org/article/c017b77a57de4b5ab731a9f29856a460
Autor:
Abdulkarim Najjar, Ans Punt, John Wambaugh, Alicia Paini, Corie Ellison, Styliani Fragki, Enrica Bianchi, Fagen Zhang, Joost Westerhout, Dennis Mueller, Hequn Li, Quan Shi, Timothy W. Gant, Phil Botham, Rémi Bars, Aldert Piersma, Ben van Ravenzwaay, Nynke I. Kramer
Publikováno v:
Archives of Toxicology 96 (2022) 12
Archives of Toxicology, 96(12), 3407-3419
Archives of Toxicology, 96(12), 3407-3419
With an increasing need to incorporate new approach methodologies (NAMs) in chemical risk assessment and the concomitant need to phase out animal testing, the interpretation of in vitro assay readouts for quantitative hazard characterisation becomes
Autor:
Amie Adkin, Timothy E.H. Allen, Felipe Alves de Almeida, Lucia E. Anelich, Mark Arnold, Sandrine Auger, Tessa Avermaete, Craig Baker-Austin, Forrest L. Bayer, Kiran N. Bhilegaonkar, Xiaoyu Bi, W. Marty Blom, Alan R. Boobis, Marija Boskovic, Hans Bouwmeester, Gary Bowering, Ioannis S. Boziaris, Christopher J. Breen, Hugo Brouwer, Ian Brown, Robert L. Buchanan, Elna M. Buys, Jane M. Caldwell, Elena Canellas, Deisy Guimarães Carneiro, Karin Carstensen, Brayan R.H. Cervantes-Huamán, Roger Clemens, Luca Cocolin, Samuel M. Cohen, David Coles, Alessia Cossettini, Natália Cruz-Martins, György Csikó, Michelle Danyluk, Wageh Sobhy Darwish, Barbara De Coninck, Christina A. Mireles DeWitt, B.C. Dlamini, John Doe, Simon Douglas Kelly, Eleonora Dupouy, Gerhard Eisenbrand, James A. Elegbeleye, Pablo Estévez, Ricardo Franco-Duarte, Leonardo Luiz de Freitas, Nigel French, Lynn J. Frewer, Yuqi Fu, Shoji Fukushima, Ana Gago-Martinez, Alejandro Dorado Garcia, Steven M. Gendel, Anne Gerardi, Anuradha Ghosh, Milica Glisic, Samuel Benrejeb Godefroy, Nigel J. Gooderham, Gerard Govers, Tomasz Grenda, F. Peter Guengerich, Sandrine Guillou, Steve Gutsell, Muriel Guyard-Nicodème, Nabila Haddad, Ndaindila N.K. Haindongo, Christie L. Harman, Thomas Hartung, A. Wallace Hayes, Graham Head, Stephen S. Hecht, Jeljer Hoekstra, Louwrens Hoffman, Olivier Honnay, Geert Houben, Jan Jetten, Shan Jin, Karen Job, Snehal Kadam, Shraddha Karanth, Agnes Karmaus, Manos Karvounis, Fumiko Kasuga, Karishma S. Kaushik, Marc C. Kennedy, John G. Keogh, Wannes Keulemans, Nida Khan, Michael E. Knowles, Dimitra Kogiannou, Serhii Kolesnyk, Rahul P. Kolhe, Timm Konold, Zoi Kotsiri, Matt Krug, Krzysztof Kwiatek, Youngjoo Kwon, Francesca Latronico, José M. Leao, Jeffrey T. LeJeune, Wenjing Li, Matthew J. Linman, Rebeca López-García, Thomas Luechtefeld, Bernadene Magnuson, Louise Manning, Nikos Manouselis, Marisa Manzano, Marco Marin, María Salomé Mariotti, Jaime Martinez-Urtaza, Lynn M. McMullen, Cronan McNamara, Angel Medina, N.N. Mehlomakulu, Jyotigna M. Mehta, Marjolein Meijerink, J. David Miller, E.N. Clare Mills, Stephen C. Mitchell, Angelo Moretto, Desmond T. Mugadza, Keya Mukherjee, Francis Z. Naab, Hanspeter Naegeli, Maristela S. Nascimento, Ivan Nastasijevic, Maarten Nauta, Lev Neretin, Cristina Nerín, Victor Ntuli, Elena G. Olson, John O’Brien, Sakshi Painuli, Efstratia Panteleli, Mihalis Papakonstantinou, Foteini F. Parlapani, Ewelina Patyra, Franco Pedreschi, Sandrine Pigat, Bert Popping, Morten Poulsen, Abani K. Pradhan, Peter Pressman, Mykola Prodanchuk, Monika Przeniosło-Siwczyńska, Ans Punt, Alfons Ramel, Abderahman Rejeb, Katherine Rich, Steven C. Ricke, Ivonne M.C.M. Rietjens, George Rigos, Carolina Ripolles-Avila, Francesco Rizzotto, Célia Fortuna Rodrigues, José Juan Rodríguez-Jerez, Martin Rose, Thomas J. Rosol, Joyjit Saha, Tor Savidge, Eyassu Seifu, Prabhakar Semwal, Thulani Sibanda, Sik Yu So, Susana Socolovsky, Giannis Stoitsis, Katelynn Stull, Marta H. Taniwaki, Sean V. Taylor, Lesa A. Thompson, Zeynal Topalcengiz, George T. Tzotzos, Michaela van den Honert, Femke L.N. Van Oijen, Maria Cristina Dantas Vanetti, Apostolos Vantarakis, Paula Vera, Jasmina Vidic, Priya Vizzini, Rosemary H. Waring, Qinglong Wu, Khaldoon Zaid-Kaylani, Tjitske Anna Zwart
Publikováno v:
Present Knowledge in Food Safety ISBN: 9780128194706
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6e011638a656534ec945d3e98a7fc8
https://doi.org/10.1016/b978-0-12-819470-6.00078-0
https://doi.org/10.1016/b978-0-12-819470-6.00078-0
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, 186(1), 18-28
Toxicological sciences : an official journal of the Society of Toxicology 186 (2022) 1
Toxicological sciences : an official journal of the Society of Toxicology 186 (2022) 1
The goal of the present study was to assess the predictive performance of a minimal generic rat physiologically based kinetic (PBK) model based on in vitro and in silico input data to predict peak plasma concentrations (Cmax) upon single oral dosing.
Autor:
Jochem, Louisse, Luca, Dellafiora, Jeroen J M W, van den Heuvel, Deborah, Rijkers, Liz, Leenders, Jean-Lou C M, Dorne, Ans, Punt, Frans G M, Russel, Jan B, Koenderink
Publikováno v:
Archives of toxicology.
Poly- and perfluoroalkyl substances (PFASs) are omnipresent in the environment and have been shown to accumulate in humans. Most PFASs are not biotransformed in animals and humans, so that elimination is largely dependent on non-metabolic clearance v
Autor:
Paul A Hepburn, Ans Punt, Alan R. Boobis, James W. Firman, Martin F. Wilks, Karma C. Fussell, Anette Thiel, Mark T. D. Cronin
Publikováno v:
Chemical Research in Toxicology 34 (2021) 2
Chemical Research in Toxicology, 34(2), 300-312
Chemical Research in Toxicology, 34(2), 300-312
The intention of this study was to determine the utility of high-throughput screening (HTS) data, as exemplified by ToxCast and Tox21, for application in toxicological read-across in food-relevant chemicals. Key questions were addressed on the extent
Publikováno v:
Chemical Research in Toxicology
Chemical Research in Toxicology 34 (2021) 2
Chemical Research in Toxicology, 34(2), 460-472
Chemical Research in Toxicology 34 (2021) 2
Chemical Research in Toxicology, 34(2), 460-472
The goal of the present study was to develop an online web-based toolbox that contains generic physiologically based kinetic (PBK) models for rats and humans, including underlying calculation tools to predict plasma protein binding and tissue:plasma