Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding

Autor: Rui-Jún Eveline Li, Aram de Haas, Ernesto Rodríguez, Hakan Kalay, Anouk Zaal, Connie R. Jimenez, Sander R. Piersma, Thang V. Pham, Alex A. Henneman, Richard R. de Goeij-de Haas, Sandra J. van Vliet, Yvette van Kooyk

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Dendritic cells (DCs) are key initiators of the adaptive immunity, and upon recognition of pathogens are able to skew T cell differentiation to elicit appropriate responses. DCs possess this extraordinary capacity to discern external signals using re

Externí odkaz: https://doaj.org/article/940058aa5a7547b08562962f35f58f1e

Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Autor: Anouk Zaal, R. J. Eveline Li, Joyce Lübbers, Sven C. M. Bruijns, Hakan Kalay, Yvette van Kooyk, Sandra J. van Vliet

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prog

Externí odkaz: https://doaj.org/article/8a27b1db633d48458fb6323a7077b1d0

Differential effects of anaphylatoxin C5a on antigen presenting cells, roles for C5aR1 and C5aR2

Autor: Anouk Zaal, Anja ten Brinke, S. Marieke van Ham

Publikováno v: Zaal, A, van Ham, S M & ten Brinke, A 2019, ' Differential effects of anaphylatoxin C5a on antigen presenting cells, roles for C5aR1 and C5aR2 ', Immunology Letters, vol. 209, pp. 45-52 . https://doi.org/10.1016/j.imlet.2019.03.014

The anaphylatoxin C5a is well-known for its role as chemoattractant and contributes to immune cell recruitment into inflamed tissue and local inflammation. C5a has recently been implicated in modulation of antigen presenting cell function, such as ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b3db7f9930ed74bc42537178d2b471
https://doi.org/10.1016/j.imlet.2019.03.014

Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding

Autor: Sander R. Piersma, Connie R. Jimenez, Sandra J. van Vliet, Thang V. Pham, Yvette van Kooyk, Rui-Jún Eveline Li, Anouk Zaal, Alex A. Henneman, Ernesto Rodríguez, Aram de Haas, Hakan Kalay, Richard R. de Haas

Publikováno v: Frontiers in Immunology
Li, R J E, de Haas, A, Rodríguez, E, Kalay, H, Zaal, A, Jimenez, C R, Piersma, S R, Pham, T V, Henneman, A A, de Goeij-de Haas, R R, van Vliet, S J & van Kooyk, Y 2021, ' Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell-Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding ', Frontiers in Immunology, vol. 12, 673454 . https://doi.org/10.3389/fimmu.2021.673454
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 12:673454. Frontiers Media S.A.

Dendritic cells (DCs) are key initiators of the adaptive immunity, and upon recognition of pathogens are able to skew T cell differentiation to elicit appropriate responses. DCs possess this extraordinary capacity to discern external signals using re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0035417a74558bbc80c64413df61478d
https://pubmed.ncbi.nlm.nih.gov/33968084

Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Autor: Joyce Lübbers, Yvette van Kooyk, Sven C. M. Bruijns, Anouk Zaal, Sandra J. van Vliet, R. J. Eveline Li, Hakan Kalay

Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, 11:305. Frontiers Media S.A.
Zaal, A, Li, R J E, Lübbers, J, Bruijns, S C M, Kalay, H, van Kooyk, Y & van Vliet, S J 2020, ' Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells ', Frontiers in Immunology, vol. 11, 305 . https://doi.org/10.3389/fimmu.2020.00305
Frontiers in Immunology

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247cedcf3fd18efd1f623ae6f5e22aaf
https://www.frontiersin.org/article/10.3389/fimmu.2020.00305/full