Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anouk A Hamers"'
Publikováno v:
Annual Review of Immunology. 37:439-456
Monocytes are innate blood cells that maintain vascular homeostasis and are early responders to pathogens in acute infections. There are three well-characterized classes of monocytes: classical (CD14+CD16− in humans and Ly6Chi in mice), intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ee3f0c59cfc096351be7814d7e13ea
https://doi.org/10.1146/annurev-immunol-042617-053119
https://doi.org/10.1146/annurev-immunol-042617-053119
Autor:
Geoffrey Neale, Kelly A. Andrews, Xiaodian Sun, Daniel E. Geraghty, Asha Pillai, Shalini Pereira, Paige Tedrick, Anouk A.J. Hamers, Kim E. Nichols, Katherine Verbist
Publikováno v:
Cytotherapy
Background aims Key obstacles in human iNKT cell translational research and immunotherapy include the lack of robust protocols for dependable expansion of human iNKT cells and the paucity of data on phenotypes in post-expanded cells. Methods We delin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d987de827b6ef67310f6220b2bfab42
https://europepmc.org/articles/PMC7666372/
https://europepmc.org/articles/PMC7666372/
Autor:
Vivian de Waard, Iker Otermin Rubio, Lejla Medzikovic, Mariska Vos, Anouk A.J. Hamers, Duco S. Koenis, Carlie J.M. de Vries, Claudia M. van Tiel, Pieter B. van Loenen, Thijs J. Beldman
Publikováno v:
Journal of biological chemistry, 293(39), 15070-15083. American Society for Biochemistry and Molecular Biology Inc.
Gene targeting via homologous recombination can occasionally result in incomplete disruption of the targeted gene. Here, we show that a widely used Nur77-deficient transgenic mouse model expresses a truncated protein encoding for part of the N-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ff0a4167c620fbfdc9444636b8dcac
https://doi.org/10.1074/jbc.ra118.002720
https://doi.org/10.1074/jbc.ra118.002720
Autor:
Catherine Nakao, Angela M. Taylor, Graham D. Thomas, Chantel McSkimming, Coleen A. McNamara, Catherine C. Hedrick, Anouk A.J. Hamers, Anh T. Nguyen, Paola Marcovecchio
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37:1548-1558
Objective— Human monocyte subsets are defined as classical (CD14 ++ CD16 − ), intermediate (CD14 ++ CD16 + ), and nonclassical (CD14 + CD16 + ). Alterations in monocyte subset frequencies are associated with clinical outcomes, including cardiovas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a180fd69ebae77f3e67a96d6d551e986
https://doi.org/10.1161/atvbaha.117.309145
https://doi.org/10.1161/atvbaha.117.309145
Publikováno v:
J Vis Exp
The intestine is the home to the largest number of immune cells in the body. The small and large intestinal immune systems police exposure to exogenous antigens and modulate responses to potent microbially derived immune stimuli. For this reason, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5afe2ec34df4f9a96fc1a8036d690a
https://pubmed.ncbi.nlm.nih.gov/31609324
https://pubmed.ncbi.nlm.nih.gov/31609324
Autor:
Paola Marcovecchio, Anh T. Nguyen, Anouk A.J. Hamers, Angela M. Taylor, Coleen A. McNamara, Chantel McSkimming, Catherine C. Hedrick, Cheryl Kim, Catherine Nakao, Huy Q. Dinh, Amy Blatchley, Graham D. Thomas
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 39(1)
Objective— Three distinct human monocyte subsets have been identified based on the surface marker expression of CD14 and CD16. We hypothesized that monocytes were likely more heterogeneous in composition. Approach and Results— We used the high di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc3718454266d48f639d4d1469b32a4
https://pubmed.ncbi.nlm.nih.gov/30580568
https://pubmed.ncbi.nlm.nih.gov/30580568
Autor:
Anouk A.J. Hamers, Asha Pillai
Publikováno v:
Sci Immunol
Glycolytic metabolism functions as a backup mechanism for M2 macrophage polarization when oxidative phosphorylation is disrupted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1594d4233d2df9009ba2baa130b4233
https://pubmed.ncbi.nlm.nih.gov/30389801
https://pubmed.ncbi.nlm.nih.gov/30389801
Autor:
Alma Zernecke, Antoine E Saliba, Huy Q. Dinh, Dennis Wolf, Catherine C. Hedrick, Natalie Hoppe, Andreas Zirlik, Klaus Ley, Anouk A.J. Hamers, Pramod Akula Bala, Ehsan Vafadarnejad, Melanie Vassalo, Clément Cochain, Konrad Buscher, Erik Ehinger, Kouji Kobiyama, Holger Winkels, Amlan K. Ghosh, Ingo Hilgendorf, Nathaly Anto Michel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Atherosclerosis, an inflammatory disease of large arteries, is - through its clinical manifestations stroke and myocardial infarction - globally the leading cause of morbidity and mortality. The interplay of pro- and anti-inflammatory leukocytes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508941802c7f913b9acd764f1b235b4b
https://doi.org/10.1161/atvb.38.suppl_1.004
https://doi.org/10.1161/atvb.38.suppl_1.004
Autor:
Akula Bala Pramod, Anouk A.J. Hamers, Konrad Buscher, Kouji Kobiyama, Alma Zernecke, Dennis Wolf, Huy Q. Dinh, Ehsan Vafadarnejad, Clément Cochain, Erik Ehinger, Antoine-Emmanuel Saliba, Andreas Zirlik, Amlan K. Ghosh, Ingo Hilgendorf, Melanie Vassallo, Catherine C. Hedrick, Klaus Ley, Nathaly Anto Michel, Natalie Hoppe, Holger Winkels
Publikováno v:
Circulation research
United States
United States
Rationale: Atherosclerosis is a chronic inflammatory disease that is driven by the interplay of pro- and anti-inflammatory leukocytes in the aorta. Yet, the phenotypic and transcriptional diversity of aortic leukocytes is poorly understood. Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90decf5de1a2ea4c4fb3fa9da7a6f6e
https://europepmc.org/articles/PMC5993603/
https://europepmc.org/articles/PMC5993603/
Autor:
Anouk A Hamers, Graham D Thomas, Cheryl Kim, Anh T Nguyen, Chantel McSkimming, Angela M Taylor, Coleen A McNamara, Catherine C Hedrick
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: Monocytes are critical to the initiation and development of atherosclerosis. To date, 3 distinct human monocyte subsets have been identified based primarily on their expression of the surface markers CD14 and CD16. With the emerging knowl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc08d84a0b3592c4c25c4a1b8629141
https://doi.org/10.1161/atvb.37.suppl_1.1
https://doi.org/10.1161/atvb.37.suppl_1.1