Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anouch Matevossian"'
Autor:
David J. Pedersen, Adilson Guilherme, Laura V. Danai, Lauren Heyda, Anouch Matevossian, Jessica Cohen, Sarah M. Nicoloro, Juerg Straubhaar, Hye Lim Noh, DaeYoung Jung, Jason K. Kim, Michael P. Czech
Publikováno v:
Molecular Metabolism, Vol 4, Iss 7, Pp 507-518 (2015)
Objective: Adipose tissue (AT) inflammation is associated with systemic insulin resistance and hyperinsulinemia in obese rodents and humans. A longstanding concept is that hyperinsulinemia may promote systemic insulin resistance through downregulatio
Externí odkaz:
https://doaj.org/article/25dbea29984f42b69a63ebc38311b475
Autor:
Kimberly A Negrin, Rachel J Roth Flach, Marina T DiStefano, Anouch Matevossian, Randall H Friedline, DaeYoung Jung, Jason K Kim, Michael P Czech
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107265 (2014)
Non-alcoholic fatty liver disease is prevalent in human obesity and type 2 diabetes, and is characterized by increases in both hepatic triglyceride accumulation (denoted as steatosis) and expression of pro-inflammatory cytokines such as IL-1β. We re
Externí odkaz:
https://doaj.org/article/66320ee6e11440dabb45ca7cea33b6bf
Autor:
Anouch Matevossian, Laura V. Danai, Jason K. Kim, Adilson L. Guilherme, Dae Young Jung, Jessica Cohen, Hye Lim Noh, Lauren Heyda, Sarah M. Nicoloro, David J. Pedersen, Juerg R. Straubhaar, Michael P. Czech
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 4, Iss 7, Pp 507-518 (2015)
Molecular Metabolism, Vol 4, Iss 7, Pp 507-518 (2015)
Objective Adipose tissue (AT) inflammation is associated with systemic insulin resistance and hyperinsulinemia in obese rodents and humans. A longstanding concept is that hyperinsulinemia may promote systemic insulin resistance through downregulation
Autor:
Abdalla Hassan, David Kearney, Anouch Matevossian, Ashraf Abugroun, Nikolaos Kakouros, Gerard P. Aurigemma, Cecilia Wong
Publikováno v:
Journal of the American College of Cardiology. 73:1204
The long term impact of the transcatheter aortic valve implantation (TAVI) on the right sided filing pressures is not clearly identified. We aimed to evaluate the effect of TAVI on the estimated pulmonary artery systolic pressure (PASP) at 1 year pos
Autor:
Kimberly A. Negrin, Anouch Matevossian, Marina T. Paul, Rachel J. Roth Flach, Thomas E. Akie, Michael P. Czech
Publikováno v:
Journal of Biological Chemistry. 288:2882-2892
Inflammation induced by wound healing or infection activates local vascular endothelial cells to mediate leukocyte rolling, adhesion, and extravasation by up-regulation of leukocyte adhesion molecules such as E-selectin and P-selectin. Obesity-associ
Autor:
Joseph C. Yawe, Lorena Garcia Menendez, Samit Kumar Bhattacharya, Christian Cortes, Myriam Aouadi, Pranitha Vangala, Anouch Matevossian, Timothy P. Fitzgibbons, Wei Zheng, Rachel J. Roth Flach, Michael P. Czech, Leonard Buckbinder, Laura V. Danai, Nana Hagan, Marcus P. Cooper, Athanasia Skoura
Publikováno v:
Nature Communications
Nature Publishing Group
Nature Publishing Group
Signalling pathways that control endothelial cell (EC) permeability, leukocyte adhesion and inflammation are pivotal for atherosclerosis initiation and progression. Here we demonstrate that the Sterile-20-like mitogen-activated protein kinase kinase
Publikováno v:
Neuropharmacology. 60:1088-1097
Rett syndrome (RTT, OMIM # 312750), a neurodevelopmental disorder of early childhood, is primarily caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MECP2). Various molecular functions have been ascribed to MECP2, including the r
Autor:
Zhiping Weng, Iris Cheung, Yan Jiang, Hennady P. Shulha, Jie Wang, Anouch Matevossian, Schahram Akbarian
Publikováno v:
Proceedings of the National Academy of Sciences. 107:8824-8829
Little is known about the regulation of neuronal and other cell-type specific epigenomes from the brain. Here, we map the genome-wide distribution of trimethylated histone H3K4 (H3K4me3), a mark associated with transcriptional regulation, in neuronal
Autor:
Frederick Albert Schroeder, Sara R. Jones, Krista L. Penta, Christine Konradi, Andrew R. Tapper, Schahram Akbarian, Anouch Matevossian
Publikováno v:
Neuropsychopharmacology. 33:2981-2992
Chromatin remodeling, including histone modification, is involved in stimulant-induced gene expression and addiction behavior. To further explore the role of dopamine D(1) receptor signaling, we measured cocaine-related locomotor activity and place p
Autor:
Jason K. Kim, Kimberly A. Negrin, Randall H. Friedline, Michael P. Czech, Anouch Matevossian, Marina T. DiStefano, Rachel J. Roth Flach, Dae Young Jung
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107265 (2014)
PLoS ONE
PLoS ONE
Non-alcoholic fatty liver disease is prevalent in human obesity and type 2 diabetes, and is characterized by increases in both hepatic triglyceride accumulation (denoted as steatosis) and expression of pro-inflammatory cytokines such as IL-1β. We re