Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anou Londesborough"'
Autor:
Niklas Ekman, Marianne Tiainen, Tea Vallenius, Pekka Katajisto, Tomi P. Mäkelä, Kari Vaahtomeri, Anou Londesborough
Publikováno v:
Development. 135:2331-2338
Inactivation of the tumor suppressor kinase Lkb1 in mice leads to vascular defects and midgestational lethality at embryonic day 9-11 (E9-E11). Here, we have used conditional targeting to investigate the defects underlying the Lkb1(-/-) phenotype. En
Autor:
Derrick J. Rossi, Eero Lehtonen, Anou Londesborough, Mark Henkemeyer, Arno Pihlak, Tomi P. Mäkelä, Nina Korsisaari
Publikováno v:
The EMBO Journal. 20:2844-2856
The trimeric Cdk7-cyclin H-Mat1 complex comprises the kinase subunit of basal transcription factor TFIIH and has been shown to function as a cyclin-dependent kinase (Cdk)-activating kinase. Herein we report that disruption of the murine Mat1 gene lea
CD2-associated protein is widely expressed and differentially regulated during embryonic development
Autor:
Anou Londesborough, Jukka Tienari, Ari Ora, Sanna Lehtonen, Ulla Pirvola, Eero Lehtonen, Ilkka Reima
Publikováno v:
Differentiation; research in biological diversity. 76(5)
CD2-associated protein (CD2AP) is an adapter protein that is involved in various signaling and vesicular trafficking processes and also functions as a linker between plasma membrane proteins and the actin cytoskeleton. The protein is known to have im