Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anookh Mohanan"'
Autor:
Deepa Joshi, Prashant Jamadarkhana, Suchit Kumbhare, Amarinder Singh, Jignesh Kotecha, Deepak Bunger, Ajay Shiwalkar, Anookh Mohanan, Chaitanya Dutt
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after co
Externí odkaz:
https://doaj.org/article/ff36814b8f394b3c9435aa0235b956ed
Autor:
Fleur van der Valk, Carlijne Hassing, Maartje Visser, Purav Thakkar, Anookh Mohanan, Kaushal Pathak, Chaitanya Dutt, Vijay Chauthaiwale, Mariette Ackermans, Aart Nederveen, Mireille Serlie, Max Nieuwdorp, Erik Stroes
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86890 (2014)
BACKGROUND AND AIMS:Obesity and its associated cardiometabolic co-morbidities are increasing worldwide. Since thyroid hormone mimetics are capable of uncoupling the beneficial metabolic effects of thyroid hormones from their deleterious effects on he
Externí odkaz:
https://doaj.org/article/1813bd211091417ab7237a0398d0b8fe
Autor:
Anookh Mohanan, Ram Gupta, Amita Dubey, Vikrant Jagtap, Appaji Mandhare, Ramesh C. Gupta, Vijay Chauthaiwale, Chaitanya Dutt
Publikováno v:
International Journal of Hypertension, Vol 2011 (2011)
In hypertensive subjects, angiotensin II and endothelin participate in a manner involving closely interwoven pathways in increasing blood pressure (BP) and inducing end organ damage. The primary objective of this study was to determine the effect of
Externí odkaz:
https://doaj.org/article/7355224542374c0793e2dd182310855b
Autor:
Deepa Joshi, Prashant GJ, Shohini Ghosh, Anookh Mohanan, Shashank Joshi, Viswanathan Mohan, Subhankar Chowdhury, Chaitanya Dutt, Nikhil Tandon
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 15:615-631
Deepa Joshi,1 Prashant GJ,1 Shohini Ghosh,1 Anookh Mohanan,1 Shashank Joshi,2 Viswanathan Mohan,3 Subhankar Chowdhury,4 Chaitanya Dutt,1 Nikhil Tandon5 1Torrent Pharmaceuticals Ltd., Ahmedabad, Gujarat, India; 2Lilavati Hospital, Mumbai, India; 3Dr.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b425577e2dd3a3924dc42401f4483d74
https://doi.org/10.2147/dmso.s330515
https://doi.org/10.2147/dmso.s330515
Autor:
Vijay Chauthaiwale, Anookh Mohanan, Appaji Baburao Mandhare, Vikrant Vijaykumar Jagtap, Amita Dubey, Ram Gupta, Ramesh C. Gupta, Chaitanya Dutt
Publikováno v:
International Journal of Hypertension, Vol 2011 (2011)
International Journal of Hypertension
International Journal of Hypertension
In hypertensive subjects, angiotensin II and endothelin participate in a manner involving closely interwoven pathways in increasing blood pressure (BP) and inducing end organ damage. The primary objective of this study was to determine the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3277248c228d4828883a8f2cbc415e8b
https://doi.org/10.4061/2011/751513
https://doi.org/10.4061/2011/751513
Publikováno v:
High Blood Pressure & Cardiovascular Prevention. 16:39-45
Background: Hypertension is a multifactorial disease, with angiotensin II (Ang II) as the established target of pharmacological intervention. However, there has been increasing interest in the biological effects of other vasoactive peptides such as e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d7e7bc89f42424ca3831e6cb233c27
https://doi.org/10.2165/00151642-200916020-00002
https://doi.org/10.2165/00151642-200916020-00002
Autor:
Shailesh Deshpande, Anita Chaudhary, Prashant G. Jamadarkhana, Anookh Mohanan, Rameshchandra Gupta, Amita Dubey, Laxmikant Chhipa
Publikováno v:
American journal of nephrology. 36(3)
Background: Hypoxia-inducible factor (HIF) transcriptional system plays a central role in cellular adaptation to low oxygen levels. Preconditional activation of HIF and/or expression of its individual target gene products leading to cytoprotection ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6e7d092590a61641063fad25047b94
https://pubmed.ncbi.nlm.nih.gov/22948183
https://pubmed.ncbi.nlm.nih.gov/22948183
Autor:
Anookh Mohanan, Chaitanya Dutt, Ram Gupta, Kumarprafull Chandra, Shitalkumar Zambad, Siralee Parikh, Vijay Chauthaiwale
Publikováno v:
Cardiomyopathies-From Basic Research to Clinical Management
1.1 Evolving profile of heart failure There have been many definitions of Heart Failure and yet the most recent definitions rely heavily on clinical manifestations: dyspnoea or undue fatigue on exertion, along with the evidence of fluid retention, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c05ce2ef1f13d8ab934724f28bae96c
https://doi.org/10.5772/28065
https://doi.org/10.5772/28065
Autor:
Vijay Chauthaiwale, Ramesh Chandra Gupta, Prashant G. Jamadarkhana, Anookh Mohanan, Prabhat Kumar, Shailesh Deshpande, Chaitanya Dutt
Publikováno v:
Neuropharmacology. 60(6)
Induction of HSPs is a natural response of stressed cells that protects against many insults including acute ischemia. TRC051384, a novel compound belonging to substituted 2-propen-1-one class is a potent inducer of heat shock protein 70 (HSP70). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a958a2b57b9bf56a3aa4b4e7a9bad5
https://pubmed.ncbi.nlm.nih.gov/21167846
https://pubmed.ncbi.nlm.nih.gov/21167846
Autor:
Maartje E. Visser, Vijay Chauthaiwale, Chaitanya Dutt, Erik S.G. Stroes, Kaushal Y. Pathak, Mireille J. Serlie, Fleur van der Valk, Mariëtte T. Ackermans, Aart J. Nederveen, Purav Thakkar, Anookh Mohanan, Carlijne Hassing, Max Nieuwdorp
Publikováno v:
PLoS ONE, 9(2). Public Library of Science
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e86890 (2014)
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e86890 (2014)
Background and aims Obesity and its associated cardiometabolic co-morbidities are increasing worldwide. Since thyroid hormone mimetics are capable of uncoupling the beneficial metabolic effects of thyroid hormones from their deleterious effects on he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c51d7df439fddaa3d72914b9c47502
https://doi.org/10.1371/journal.pone.0086890
https://doi.org/10.1371/journal.pone.0086890