Protective effect of PDE4B subtype-specific inhibition in an Appknock-in mouse model for Alzheimer’s disease

Autor: Armstrong, Paul, Güngör, Hüseyin, Anongjanya, Pariya, Tweedy, Clare, Parkin, Edward, Johnston, Jamie, Carr, Ian M., Dawson, Neil, Clapcote, Steven J.

Publikováno v: Neuropsychopharmacology; 20240101, Issue: Preprints p1-10, 10p

Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer's disease.

Autor: Armstrong P; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK., Güngör H; Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, LA1 4YG, Lancaster, UK.; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Cumhuriyet University, Sivas, 58140, Turkey., Anongjanya P; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK., Tweedy C; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK., Parkin E; Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, LA1 4YG, Lancaster, UK., Johnston J; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK., Carr IM; Leeds Institute of Medical Research, University of Leeds, LS9 7TF, Leeds, UK., Dawson N; Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, LA1 4YG, Lancaster, UK., Clapcote SJ; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK. s.j.clapcote@leeds.ac.uk.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2024 Sep; Vol. 49 (10), pp. 1559-1568. Date of Electronic Publication: 2024 Mar 23.