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pro vyhledávání: '"Annuradha Jain"'
Autor:
Yibin Xiang, Hans-Peter Biemann, Tatiana Gladysheva, Markus Metz, J. David Stepp, Renato Skerlj, Andrew T Papoulis, Andrew C. Good, Kimberly Bishop, Annuradha Jain, Gary Asmussen, Bradford H. Hirth, Katherine Jancsics, Maria Fitzgerald, Ronnie Wei, Jinyu Liu
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(10)
Novel benzofuran-2-carboxylic acids, exemplified by 29, 38 and 39, have been discovered as potent Pim-1 inhibitors using fragment based screening followed by X-ray structure guided medicinal chemistry optimization. The compounds demonstrate potent in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f2a70806999950d2d3da86a2785090
https://pubmed.ncbi.nlm.nih.gov/21507633
https://pubmed.ncbi.nlm.nih.gov/21507633
