Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Annunziata Cascone"'
Publikováno v:
Cells, Vol 11, Iss 10, p 1703 (2022)
LACTB is a relatively unknown mitochondrial protein structurally related to the bacterial penicillin-binding and beta-lactamase superfamily of serine proteases. LACTB has recently gained an increased interest due to its potential role in lipid metabo
Externí odkaz:
https://doaj.org/article/9c250afdace143eeb049119d50310ab6
Autor:
Giulio Calza, Elisabeth Nyberg, Matias Mäkinen, Rabah Soliymani, Annunziata Cascone, Dan Lindholm, Emanuele Barborini, Marc Baumann, Maciej Lalowski, Ove Eriksson
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Metformin is the first line drug for type 2 diabetes but its molecular mechanisms remain unclear. Here, we have studied the acute effect of a therapeutically relevant intrahepatic concentration of metformin on glucose production from lactate. We sele
Externí odkaz:
https://doaj.org/article/34a02892da69404dad71df530c58a0df
c-Abl inhibitors enable insights into the pathophysiology and neuroprotection in Parkinson’s disease
Autor:
Dan Lindholm, Dan Duc Pham, Annunziata Cascone, Ove Eriksson, Krister Wennerberg, Mart Saarma
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Parkinson’s disease (PD) is a progressive neurodegenerative disorder causing movement disabilities and several non-motor symptoms in afflicted patients. Recent studies in animal models of PD and analyses of brain specimen from PD patients revealed
Externí odkaz:
https://doaj.org/article/15e29f3c636941be8274da118b910165
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35357 (2012)
BackgroundExtensive DNA damage leads to apoptosis. Histones play a central role in DNA damage sensing and may mediate signals of genotoxic damage to cytosolic effectors including mitochondria.Methodology/principal findingsWe have investigated the eff
Externí odkaz:
https://doaj.org/article/db81b922028b4698be8b8a5c99af8b66
Autor:
Luca Bevilacqua, Nicola Capuano, Annunziata Cascone, Federico Ceccarini, Fabio Corvino, Ciro D'Apice, Ivano De Furio, Giovanna Scafuro, Gianluca Supino
Publikováno v:
Je-LKS: Journal of E-Learning and Knowledge Society, Vol 5, Iss 3 (2009)
This paper outlines an original approach to e-learning systems which integrates the most recent results in the feld of human-computer interaction. Notably it will show the applicability of multimodal, attentive, affective and perceptual user interfac
Externí odkaz:
https://doaj.org/article/e5cc4bd257514d27b73154897747e8fb
Publikováno v:
Journal of Mathematical Sciences. 196:23-29
Simulation allows one to realize models of complex systems, processes, or components and carry out experiments on them with the purpose to determine how the real systems perform. The aim of this paper is to present a simulator able to analyze the sto
c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s Disease
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
Parkinson's disease (PD) is a progressive neurodegenerative disorder causing movement disabilities and several non-motor symptoms in afflicted patients. Recent studies in animal models of PD and analyses of brain specimen from PD patients revealed an
Publikováno v:
Automation and Remote Control. 72:99-110
Consideration was given to the discrete-time queuing system with inversive servicing without interrupts, second-order geometrical arrivals, arbitrary (discrete) distribution of the customer length, and finite buffer. Each arriving customer has length
Autor:
Elisabeth Nyberg, Maciej Lalowski, Matias Mäkinen, Dan Lindholm, Annunziata Cascone, Ove Eriksson, Emanuele Barborini, Marc Baumann, Rabah Soliymani, Giulio Calza
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e87
Publikováno v:
Discrete & Continuous Dynamical Systems - B. 13:59-78
This paper concerns optimization of data traffic flows on a telecommunication network, modelled using a fluid - dynamic approach. Flows can be controlled adjusting traffic distribution and priority parameters. Two cost functionals are considered, whi