Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Annoor Awadasseid"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116257- (2024)
In recent years, several monoclonal antibodies (mAbs) targeting PD-L1 have been licensed by the FDA for use in the treatment of cancer, demonstrating the effectiveness of blocking immune checkpoints, particularly the PD-1/PD-L1 pathway. Although mAb-
Externí odkaz:
https://doaj.org/article/bff2fc1956e042578c9989b27b859fdf
Autor:
Hua Zhang, Shi-Jia Zhou, Chen-Feng Shen, Yong-Nan Zhou, Cai-Yun Wu, Meng-Yu Zhu, Qi-Meng Yu, Annoor Awadasseid, Yan-Ling Wu, Wen Zhang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Recent studies on biphenyl-containing compounds, a type of PD-1/PD-L1 blocker which binds to PD-L1 and induces dimerisation, have focussed on its immune function. Herein, 10 novel biphenyl derivatives were designed and synthesised. The results of the
Externí odkaz:
https://doaj.org/article/9d7cce7ff27c465eb153017393b673d4
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114057- (2023)
PD-1 (Programmed cell death-1) is a receptor that inhibits the activation of T cells and is an important target for cancer immunotherapy. PD-1 expression stays high on antigen-specific T cells that have been stimulated for a long time, making them le
Externí odkaz:
https://doaj.org/article/4007e3093fa74a2fa3a19ec8a9d6ebb4
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112764- (2022)
Externí odkaz:
https://doaj.org/article/996aa7e35ab74df6bac080e69d5c9a6e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 111957- (2021)
The outbreak of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, in December 2019, and its global dissemination became the coronavirus disease 2019 (COVID-19) pandemic declared by the World Health Organization (WHO) on 11
Externí odkaz:
https://doaj.org/article/2c6937d66fc94d09b5d91ce4c8eac73e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111550- (2021)
G-quadruplexes (G4) are secondary four-stranded DNA helical structures consisting of guanine-rich nucleic acids, which can be formed in the promoter regions of several genes under proper conditions. Several cancer cells have been shown to emerge from
Externí odkaz:
https://doaj.org/article/fff0cbe337f847eeb2e2a6f599cb9e4a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111330- (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causal factor of the coronavirus disease 2019 (COVID-19). Drug repurposing, portraying patented drugs as a successful drug development technique, could shorten the period and minimize
Externí odkaz:
https://doaj.org/article/f81c7d80d417464ca5e9bb97de9b5ae5
Autor:
Mohnad Abdalla, Wafa Ali Eltayb, Amr Ahmed El-Arabey, Raihan Mo, T. I. M. Dafaalla, Hamed I. Hamouda, Eijaz Ahmed Bhat, Annoor Awadasseid, Hassan Abdellha Ahmed Ali
Publikováno v:
Genes and Environment, Vol 40, Iss 1, Pp 1-9 (2018)
Abstract Background Grx6 is a yeast Golgi/endoplasmic reticulum protein involved in iron-sulfur binding that belongs to monothiol glutaredoxin-protein family. Grx6 has been biochemically characterized previously. Grx6 contains a conserved cysteine re
Externí odkaz:
https://doaj.org/article/6cc470f09d204068a188a4d75c46eb7b
Publikováno v:
Cells, Vol 10, Iss 10, p 2533 (2021)
Exosomes are extracellular vesicles released by most of the eukaryotic cells. Exosomes’ components include proteins, lipids, microRNA, circular RNA, long noncoding RNA, DNA, etc. Exosomes may carry both pro and anti-inflammatory cargos; however, ex
Externí odkaz:
https://doaj.org/article/c449b2bdd7124e5498af47f7713ee185
Autor:
Annoor Awadasseid, Jie Hou, Yaser Gamallat, Shang Xueqi, Kuugbee D Eugene, Ahmed Musa Hago, Djibril Bamba, Abdo Meyiah, Chiwala Gift, Yi Xin
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171270 (2017)
Cancer is one of the most common causes of deaths worldwide. Herein, we report an efficient natural anticancer glucan (CVG) extracted from Coriolus Versicolar (CV). CVG was extracted by the hot water extraction method followed by ethanol precipitatio
Externí odkaz:
https://doaj.org/article/1dc9551f73144991a7043e5e473de914