Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annmarie L. Saab"'
Autor:
Deborah L. Smith, Lee E. Schechter, Michael Z. Kagan, Nicole T. Hatzenbuhler, Amedeo Arturo Failli, Deborah Ann Evrard, Zhang Minsheng, Jeannette Golembieski, Richard Eric Mewshaw, Margaret Lai, Steven Edward Lenicek, Michael Chlenov, Jean Sze, Terrance H. Andree, Dahui Zhou, Annmarie L. Saab, Geoffrey Hornby, Reinhardt Bernhard Baudy, Boyd L. Harrison, Uresh Shantilal Shah, Kelly Sullivan
Publikováno v:
Journal of Medicinal Chemistry. 51:6980-7004
Novel compounds combining a 5-HT 1A moiety (3-aminochroman scaffold) and a 5-HT transporter (indole analogues) linked through a common basic nitrogen via an alkyl chain attached at the 1- or 3-position of the indole were evaluated for dual affinity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0888e59808afb3d9088f68290cf3d60e
https://doi.org/10.1021/jm8007097
https://doi.org/10.1021/jm8007097
Autor:
Deborah L. Smith, Annmarie L. Saab, Heidi van der Lee, Terrance H. Andree, Wayne E. Childers, Zoe A. Hughes, Meiyi Zhang, Thomas A. Comery, Suzan Aschmies, John Kao, Michael G. Kelly, Lee E. Schechter, Warren D. Hirst, Sharon Rosenzweig-Lipson, Lee A. Dawson, Stacey J. Sukoff Rizzo, Mark Day, Cesario O. Tio, Steven M. Grauer, Kelly Sullivan, Irene B. Feingold, Boyd L. Harrison
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 325:134-145
5-Hydroxytryptamine (5-HT) 1A receptors play an important role in multiple cognitive processes, and compelling evidence suggests that 5-HT 1A antagonists can reverse cognitive impairment. We have examined the therapeutic potential of a potent ( K i =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2afe00ebb88c6f091a09af7c416f2132
https://doi.org/10.1124/jpet.107.133082
https://doi.org/10.1124/jpet.107.133082
Autor:
Warren D, Hirst, Terrance H, Andree, Suzan, Aschmies, Wayne E, Childers, Thomas A, Comery, Lee A, Dawson, Mark, Day, Irene B, Feingold, Steven M, Grauer, Boyd L, Harrison, Zoë A, Hughes, John, Kao, Michael G, Kelly, Heidi, van der Lee, Sharon, Rosenzweig-Lipson, Annmarie L, Saab, Deborah L, Smith, Kelly, Sullivan, Stacey J Sukoff, Rizzo, Cesario, Tio, Mei-Yi, Zhang, Lee E, Schechter
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 325(1)
5-Hydroxytryptamine (5-HT)(1A) receptors play an important role in multiple cognitive processes, and compelling evidence suggests that 5-HT(1A) antagonists can reverse cognitive impairment. We have examined the therapeutic potential of a potent (K(i)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f7ea980c14b207af60e5928c9242743
https://pubmed.ncbi.nlm.nih.gov/18182558
https://pubmed.ncbi.nlm.nih.gov/18182558