Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Annkristin Heine"'
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/dbde80898ef5402090d16f87a166c077
Autor:
Rebekka Mispelbaum, Tessa Hattenhauer, Franz-Georg Bauernfeind, Jan-Frederic Lau, Peter Brossart, Annkristin Heine
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
In the setting of metastatic adrenocortical cancer, there are limited therapy options such as mitotane and platinum-based chemotherapy with only low response rates. Ipilimumab and nivolumab are approved for several solid cancer types. Tumor mutationa
Externí odkaz:
https://doaj.org/article/da2771142a4841c2a2ee8d6f51af0ae3
Autor:
Tanja Fetter, Simon Fietz, Maya Bertlich, Christine Braegelmann, Luka de Vos-Hillebrand, Joerg Wenzel, Annkristin Heine, Jennifer Landsberg, Philipp Jansen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionOver the past decade, immune checkpoint inhibitors such as antibodies against cytotoxicity T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) have become an important armamentarium against a broad spectr
Externí odkaz:
https://doaj.org/article/5b1358c322a14c438a32a1c798e8b362
Autor:
Annkristin Heine, Niels A. W. Lemmermann, Chrystel Flores, Janine Becker-Gotot, Natalio Garbi, Peter Brossart, Christian Kurts
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionProphylactic vaccines generate strong and durable immunity to avoid future infections, whereas post-exposure vaccinations are intended to establish rapid protection against already ongoing infections. Antiviral cytotoxic CD8+ T cells (CTL
Externí odkaz:
https://doaj.org/article/051e31edb5824e1484a74bf513adbdb8
Autor:
Annkristin Heine, Stefanie Andrea Erika Held, Solveig Nora Daecke, Chrystel Flores, Peter Brossart
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSeveral anaplastic lymphoma kinase (ALK)-inhibitors (ALKi) have been approved for the treatment of ALK-translocated advanced or metastatic Non Small Cell Lung Cancer (NSCLC), amongst crizotinib and alectinib. This forces physicians to cho
Externí odkaz:
https://doaj.org/article/af57a727ecae4f81a24f43ecce0cfebe
Autor:
Mümtaz Köksal, Oğuzhan Özkan, Tobias Holderried, Annkristin Heine, Peter Brossart, Ahmed Gawish, Davide Scafa, Gustavo R. Sarria, Christina Leitzen, Leonard C. Schmeel, Thomas Müdder
Publikováno v:
Cancers, Vol 15, Iss 17, p 4220 (2023)
Modern irradiation techniques for optimized conformal TBI can be realized by Helical Tomotherapy (HT) or Volumetric Modulated Arc Therapy (VMAT), depending on the availability of suitable specialized equipment. In this dosimetric planning study, we c
Externí odkaz:
https://doaj.org/article/3bce0aef7c3644fbb213a008184be99e
Autor:
Rebekka Mispelbaum, Sandra Tessa Hattenhauer, Stefanie Andrea Erika Held, Peter Brossart, Annkristin Heine
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe use of immunotherapy (IT) is rapidly increasing across different tumor entities. PD-L1 expression is primarily used for therapy evaluation. The disadvantages of PD-L1 status are spatial and temporal heterogeneity as well as tumor type-d
Externí odkaz:
https://doaj.org/article/5e7515240e014904aadf76a896a7182a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Red blood cell (RBC) transfusions have been shown to exert immunosuppressive effects in different diseases. In consequence, RBC transfusions might also negatively influence the response to immunotherapeutic treatment approaches. To address how RBC tr
Externí odkaz:
https://doaj.org/article/0fadd418522849c6a01f8ea4c54a8de4
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Nucleic acids can fold into non-canonical secondary structures named G-quadruplexes (G4s), which consist of guanine-rich sequences stacked into guanine tetrads stabilized by Hoogsteen hydrogen bonding, π-π interactions, and mono
Externí odkaz:
https://doaj.org/article/434443b8e28f4375a881de111208c1f0
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract In vitro-transcribed messenger RNA-based therapeutics represent a relatively novel and highly efficient class of drugs. Several recently published studies emphasize the potential efficacy of mRNA vaccines in treating different types of malig
Externí odkaz:
https://doaj.org/article/158216bf52054bf8bee5dfe9287bddb1