Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Annita Ngatchou Weiss"'
Publikováno v:
Biophysical Journal. 107:16-25
We investigated the basis for previous observations that fluorescent-labeled neuropeptide Y (NPY) is usually released within 200 ms after fusion, whereas labeled tissue plasminogen activator (tPA) is often discharged over many seconds. We found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0e82f6c23417440e9e69def705f93f
https://doi.org/10.1016/j.bpj.2014.04.063
https://doi.org/10.1016/j.bpj.2014.04.063
Publikováno v:
Biophysical Journal. 107:26-33
It is often assumed that upon fusion of the secretory granule membrane with the plasma membrane, lumenal contents are rapidly discharged and dispersed into the extracellular medium. Although this is the case for low-molecular-weight neurotransmitters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9234aff5cefca5832c19c3e9a22979e
https://doi.org/10.1016/j.bpj.2014.04.064
https://doi.org/10.1016/j.bpj.2014.04.064
Autor:
Annita Ngatchou Weiss, Trine Lisberg Toft-Bertelsen, Julia Kurps, Jakob B. Sørensen, Juliane Lauks, Alexander M. Walter, Alexander Schulz, Iwona Ziomkiewicz, Heidi de Wit, Gabriele Fischer von Mollard, Susanne Schöning, Matthijs Verhage
Publikováno v:
Walter, A M, Kurps, J, de Wit, H, Schöning, S, Toft-Bertelsen, R L, Lauks, J, Ziomkiewicz, I, Weiss, A N, Schulz, A, Fischer von Mollard, G, Verhage, M & Sørensen, J B 2014, ' The SNARE protein vti1a functions in dense-core vesicle biogenesis ', EMBO Journal, vol. 33, no. 15, pp. 1681-1697 . https://doi.org/10.15252/embj.201387549
EMBO Journal, 33(15), 1681-1697. Nature Publishing Group
EMBO Journal, 33(15), 1681-1697. Wiley-Blackwell
EMBO Journal, 33(15), 1681-1697. Nature Publishing Group
EMBO Journal, 33(15), 1681-1697. Wiley-Blackwell
The SNARE protein vti1a is proposed to drive fusion of intracellular organelles, but recent data also implicated vti1a in exocytosis. Here we show that vti1a is absent from mature secretory vesicles in adrenal chromaffin cells, but localizes to a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93162c2f07a023de92f404a0c190724
https://hdl.handle.net/1871.1/7524140a-d2d7-4473-a539-f3cfaccedd41
https://hdl.handle.net/1871.1/7524140a-d2d7-4473-a539-f3cfaccedd41
Publikováno v:
Biophysical Journal. 106(2)
We evaluated the importance on post-fusion discharge rates of the mobility of specific lumenal proteins within chromaffin granules in living cells. Two fluorescent proteins were investigated: tissue plasminogen activator (tPA-cerulean), which is disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4f76286e5b6561319a0867f3b0d606
Publikováno v:
Biophysical Journal. 104:619a
Although a great deal is known about events leading to the release of secretory granule contents into the extracellular space, little is known about the physical state of the granule lumenal contents prior to exocytosis. We have used TIRFM as our cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812cfcda1ca416a26292017b801869dd
https://doi.org/10.1016/j.bpj.2012.11.3427
https://doi.org/10.1016/j.bpj.2012.11.3427