Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Annika von Seggern"'
Autor:
Dandan Han, Lars Schomacher, Katrin M Schüle, Medhavi Mallick, Michael U Musheev, Emil Karaulanov, Laura Krebs, Annika von Seggern, Christof Niehrs
Publikováno v:
eLife, Vol 8 (2019)
Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and epigenetic gene regulation. This dual role raises the question if phenotypic abnormalities resulting from deficiency of BER
Externí odkaz:
https://doaj.org/article/bc4ad1438cc94abd8d81ba2802e6ceab
Autor:
Laura Krebs, Emil Karaulanov, Katrin M. Schüle, Christof Niehrs, Annika von Seggern, Lars Schomacher, Medhavi Mallick, Michael U. Musheev, Dandan Han
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b599c9b1c7ae613958c88d928166fa
https://doi.org/10.7554/elife.49044.038
https://doi.org/10.7554/elife.49044.038
Publikováno v:
Developmental Cell
SummaryMale sex determination in mammals is induced by Sry, a gene whose regulation is poorly understood. Here we show that mice mutant for the stress-response gene Gadd45g display complete male-to-female sex reversal. Gadd45g and Sry have a striking
Autor:
Khelifa Arab, Christof Niehrs, Sabine Kienhöfer, Lars Schomacher, Annika von Seggern, Michael U. Musheev, Dandan Han
Publikováno v:
Nature structural & molecular biology
DNA 5-methylcytosine is a dynamic epigenetic mark which plays important roles in development and disease. In the Tet-Tdg demethylation pathway, methylated cytosine is iteratively oxidized by Tet dioxygenases and unmodified cytosine is restored via th