Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Annika Wiedemann"'
Autor:
Marta Ferreira-Gomes, Yidan Chen, Pawel Durek, Hector Rincon-Arevalo, Frederik Heinrich, Laura Bauer, Franziska Szelinski, Gabriela Maria Guerra, Ana-Luisa Stefanski, Antonia Niedobitek, Annika Wiedemann, Marina Bondareva, Jacob Ritter, Katrin Lehmann, Sebastian Hardt, Christian Hipfl, Sascha Hein, Eberhard Hildt, Mareen Matz, Henrik E. Mei, Qingyu Cheng, Van Duc Dang, Mario Witkowski, Andreia C. Lino, Andrey Kruglov, Fritz Melchers, Carsten Perka, Eva V. Schrezenmeier, Andreas Hutloff, Andreas Radbruch, Thomas Dörner, Mir-Farzin Mashreghi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Bone marrow plasma cells (BMPC) are the correlate of humoral immunity, consistently releasing antibodies into the bloodstream. It remains unclear if BMPC reflect different activation environments or maturation of their precursors. Here we de
Externí odkaz:
https://doaj.org/article/6afb3ecd327947ce81ffe2bed6522ae5
Autor:
Hector Rincon-Arevalo, Ana-Luisa Stefanski, Tuan Anh Le, Marcos Cases, Annika Wiedemann, Franziska Szelinski, Jacob Ritter, Van Duc Dang, Andreia C. Lino, Thomas Dörner, Eva Schrezenmeier
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Memory B cells (mBCs) are characterized by their long-term stability, fast reactivation, and capability to rapidly differentiate into antibody-secreting cells (ASCs). However, the role of T cells in the differentiation of mBCs, in contrast to naive B
Externí odkaz:
https://doaj.org/article/7a594cb5eb1e42ba98d13e234f77e8cc
Autor:
Gino Kwon, Annika Wiedemann, Lisa M. Steinheuer, Ana-Luisa Stefanski, Franziska Szelinski, Tomas Racek, Andreas Philipp Frei, Klas Hatje, Tony Kam-Thong, David Schubert, Thomas Schindler, Thomas Dörner, Kevin Thurley
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) share clinical as well as pathogenic similarities. Although previous studies suggest various abnormalities in different immune cell compartments, dedicated cell-type
Externí odkaz:
https://doaj.org/article/d842d9b1ede44c8c9b4c539caeb38071
Autor:
Tobias Alexander, Thomas Dörner, Franziska Szelinski, Andreia C Lino, Karin Reiter, Annika Wiedemann, Sebastian Fuchs, Ana-Luisa Stefanski, Eva Vanessa Schrezenmeier, Hector Rincon-arevalo, Jacob Ritter, Marie Lettau, Duc Van Dang, Andreas P Frei
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0c4e5e03657d4a2ca9407037720619d6
Autor:
Annika Wiedemann, Marie Lettau, Sarah Y. Weißenberg, Ana-Luisa Stefanski, Eva-Vanessa Schrezenmeier, Hector Rincon-Arevalo, Karin Reiter, Tobias Alexander, Falk Hiepe, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B- and T-lymphocyte attenuator (BTLA/CD272) is an inhibitory checkpoint molecule expressed on T and B cells. Prior studies reported defective function of BTLA by T cells in patients with systemic lupus erythematosus (SLE), whereas nothing is known ab
Externí odkaz:
https://doaj.org/article/0d325ee477fd4493886422919bf70fff
Autor:
Hector Rincon-Arevalo, Annika Wiedemann, Ana-Luisa Stefanski, Marie Lettau, Franziska Szelinski, Sebastian Fuchs, Andreas Philipp Frei, Malte Steinberg, Tony Kam-Thong, Klas Hatje, Baerbel Keller, Klaus Warnatz, Andreas Radbruch, Andreia C. Lino, Eva Schrezenmeier, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Circulating CD11c+ B cells are a key phenomenon in certain types of autoimmunity but have also been described in the context of regular immune responses (i.e., infections, vaccination). Using mass cytometry to profile 46 different markers on individu
Externí odkaz:
https://doaj.org/article/880ec4a29f2f4fdd9fe4bdff19f5ee45
Autor:
Annika Wiedemann, Marie Lettau, Ina Wirries, Annemarie Jungmann, Abdulrahman Salhab, Gilles Gasparoni, Henrik E. Mei, Carsten Perka, Jörn Walter, Andreas Radbruch, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The functions of bone marrow plasma cells (BMPC) beyond antibody production are not fully elucidated and distinct subsets of BMPC suggest potential different functions. Phenotypic differences were identified for human BMPC depending on CD19 expressio
Externí odkaz:
https://doaj.org/article/e0343bc094fc42fb81cd129a2e315050
Autor:
Marie Lettau, Annika Wiedemann, Eva Vanessa Schrezenmeier, Claudia Giesecke-Thiel, Thomas Dörner
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229778 (2020)
BACKGROUND:Memory B cell (mBC) induction and maintenance is one of the keys to long-term protective humoral immunity. MBCs are fundamental to successful medical interventions such as vaccinations and therapy in autoimmunity. However, their lifestyle
Externí odkaz:
https://doaj.org/article/7796f4c22d1d44ab88eede04d2cea4a5
Autor:
Sarah Y. Weißenberg, Franziska Szelinski, Eva Schrezenmeier, Ana-Luisa Stefanski, Annika Wiedemann, Hector Rincon-Arevalo, Anna Welle, Annemarie Jungmann, Karl Nordström, Jörn Walter, Juliana Imgenberg-Kreuz, Gunnel Nordmark, Lars Rönnblom, Prathyusha Bachali, Michelle D. Catalina, Amrie C. Grammer, Peter E. Lipsky, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoimmune diseases (AID) such as systemic lupus erythematosus (SLE), primary Sjögren's syndrome (pSS), and rheumatoid arthritis (RA) are chronic inflammatory diseases in which abnormalities of B cell function play a central role. Although it is wid
Externí odkaz:
https://doaj.org/article/d9ed2fdab4744e97827ac0c5501dd134
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212525 (2019)
The bone marrow (BM) is, in addition to being the site of B cell development, a tissue that harbors long-lived plasma cells (PC), the cells that protect the body against foreign antigens by continuous production of antibodies. Nothing is known about
Externí odkaz:
https://doaj.org/article/9b6ca895048643fc8b494933cc5fe8a7