Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Annika Wahlström"'
Autor:
Annika Wahlström, Ariel Brumbaugh, Wilhelm Sjöland, Lisa Olsson, Hao Wu, Marcus Henricsson, Annika Lundqvist, Kassem Makki, Stanley L. Hazen, Göran Bergström, Hanns-Ulrich Marschall, Michael A. Fischbach, Fredrik Bäckhed
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Alterations in gut microbiota composition are suggested to contribute to cardiometabolic diseases, in part by producing bioactive molecules. Some of the metabolites are produced by very low abundant bacterial taxa, which largely have been ne
Externí odkaz:
https://doaj.org/article/7c3061f41e2741e1be79161e6894712b
Autor:
Annika Wahlström, Ömrüm Aydin, Lisa M. Olsson, Wilhelm Sjöland, Marcus Henricsson, Annika Lundqvist, Hanns-Ulrich Marschall, Rutger Franken, Arnold van de Laar, Victor Gerdes, Abraham S. Meijnikman, Dag Hofsø, Albert K. Groen, Jøran Hjelmesæth, Max Nieuwdorp, Fredrik Bäckhed
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105265- (2024)
Summary: Background: Bariatric surgery is an effective treatment option for obesity and provides long-term weight loss and positive effects on metabolism, but the underlying mechanisms are poorly understood. Alterations in bile acid metabolism have b
Externí odkaz:
https://doaj.org/article/64840ca30a314f63b2613355386bee20
Autor:
Claudia D. Fuchs, Emmanuel D. Dixon, Tim Hendrikx, Veronika Mlitz, Annika Wahlström, Marcus Ståhlman, Hubert Scharnagl, Tatjana Stojakovic, Christoph J. Binder, Hanns‐Ulrich Marschall, Michael Trauner
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2368-2378 (2022)
Abstract Bile salt export pump (Bsep) (Abcb11)−/− mice are protected from acquired cholestatic injury due to metabolic preconditioning with a hydrophilic bile acid (BA) pool with formation of tetrahydroxylated bile acids (THBAs). We aimed to expl
Externí odkaz:
https://doaj.org/article/2eb49cbe92514bb2bf2ca7d245d3ffe7
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 70-75 (2017)
Humans and mice differ substantially in their bile acid profiles as mice in addition to cholic acid (CA) predominantly synthesize 6β-hydroxylated muricholic acids (MCAs) whereas humans produces chenodeoxycholic acid (CDCA) and CA as primary bile aci
Externí odkaz:
https://doaj.org/article/ca20225155c145ab9aa9deda94ea35d9
Autor:
Annika Wahlström, Petia Kovatcheva-Datchary, Marcus Ståhlman, Muhammad-Tanweer Khan, Fredrik Bäckhed, Hanns-Ulrich Marschall
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 2, Pp 412-419 (2017)
The gut microbiota influences the development and progression of metabolic diseases partly by metabolism of bile acids (BAs) and modified signaling through the farnesoid X receptor (FXR). In this study, we aimed to determine how the human gut microbi
Externí odkaz:
https://doaj.org/article/a67b6b21e24b47a494f4720dc7d74bef
Autor:
Petia Kovatcheva-Datchary, Saeed Shoaie, Sunjae Lee, Annika Wahlström, Intawat Nookaew, Anna Hallen, Rosie Perkins, Jens Nielsen, Fredrik Bäckhed
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3772-3783.e6 (2019)
Summary: The gut microbiota can modulate human metabolism through interactions with macronutrients. However, microbiota-diet-host interactions are difficult to study because bacteria interact in complex food webs in concert with the host, and many of
Externí odkaz:
https://doaj.org/article/83a39968fbf24982bd3018fcb9ab8f2e
Autor:
Kassem Makki, Harald Brolin, Natalia Petersen, Marcus Henricsson, Dan Ploug Christensen, Muhammad Tanweer Khan, Annika Wahlström, Per-Olof Bergh, Valentina Tremaroli, Kristina Schoonjans, Hanns-Ulrich Marschall, Fredrik Bäckhed
Publikováno v:
Gut, 72 (2)
Makki, K, Brolin, H, Petersen, N, Henricsson, M, Christensen, D P, Khan, M T, Wahlström, A, Bergh, P-O, Tremaroli, V, Schoonjans, K, Marschall, H-U & Bäckhed, F 2023, ' 6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice ', Gut, vol. 72, pp. 314-324 . https://doi.org/10.1136/gutjnl-2021-326541
Makki, K, Brolin, H, Petersen, N, Henricsson, M, Christensen, D P, Khan, M T, Wahlström, A, Bergh, P-O, Tremaroli, V, Schoonjans, K, Marschall, H-U & Bäckhed, F 2023, ' 6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice ', Gut, vol. 72, pp. 314-324 . https://doi.org/10.1136/gutjnl-2021-326541
Objective Dietary fibres are essential for maintaining microbial diversity and the gut microbiota can modulate host physiology by metabolising the fibres. Here, we investigated whether the soluble dietary fibre oligofructose improves host metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bf96e61639223e36cacfb3ff99cc01
https://hdl.handle.net/20.500.11850/553802
https://hdl.handle.net/20.500.11850/553802
Autor:
Caroline Ovadia, Georgia Papacleovoulou, Catherine Williamson, Julian R. Marchesi, Vanessa Pataia, Julie A. K. McDonald, Saraid McIlvride, Hanns-Ulrich Marschall, David Shapiro, Eugène H.J.M. Jansen, Annika Wahlström, Luciano Adorini
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology
Pataia, V, Mcilvride, S, Papacleovoulou, G, Ovadia, C, Mcdonald, J A K, Wahlström, A, Jansen, E, Adorini, L, Shapiro, D, Marchesi, J R, Marschall, H & Williamson, C 2020, ' Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia ', AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 319, no. 2, pp. G197-G211 . https://doi.org/10.1152/ajpgi.00126.2020
Pataia, V, Mcilvride, S, Papacleovoulou, G, Ovadia, C, Mcdonald, J A K, Wahlström, A, Jansen, E, Adorini, L, Shapiro, D, Marchesi, J R, Marschall, H & Williamson, C 2020, ' Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia ', AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 319, no. 2, pp. G197-G211 . https://doi.org/10.1152/ajpgi.00126.2020
Intrahepatic cholestasis of pregnancy (ICP) is characterized by elevated maternal circulating bile acid levels and associated dyslipidemia. ICP leads to accumulation of bile acids in the fetal compartment, and the elevated bile acid concentrations ar
Autor:
Thierry Claudel, Tatjana Stojakovic, Michael Trauner, Marcus Ståhlman, Hanns-Ulrich Marschall, Hubert Scharnagl, Veronika Mlitz, Claudia D. Fuchs, Sebastian Krivanec, Annika Wahlström, Daniel Steinacher
Publikováno v:
Liver International
Background Bile acids (BAs) regulate hepatic lipid metabolism and inflammation. Bile salt export pump (BSEP) KO mice are metabolically preconditioned with a hydrophilic BA composition protecting them from cholestasis. We hypothesize that changes in h
Autor:
Carolin V. Schneider, Hanns-Ulrich Marschall, Ahmed Ghallab, Reham Hassan, Annika Wahlström, Dirk Drasdo, Tom H. Karlsen, Maiju Myllys, Till Strowig, Konrad Kilic, Ejc Galvez, Christian Trautwein, Kai Markus Schneider, Maximilian Hatting, Antonio Molinaro, Jan G. Hengstler, Johannes R. Hov, Sebastian Zühlke, Marcus Henricsson, M. Frissen, Lena Susanna Candels, C Elfers, A Zaza, Lijun Liao, Antje Mohs
Publikováno v:
Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).