Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annika Trei"'
Autor:
Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA int
Externí odkaz:
https://doaj.org/article/50205bb260684d2cbb3e422b4eefcc20
Autor:
Ade Kallas-Kivi, Annika Trei, Artjom Stepanjuk, Katrin Ruisu, Keiu Kask, Margus Pooga, Toivo Maimets
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
The maintenance of the pluripotency of human embryonic stem (hES) cells requires special conditions for culturing. These conditions include specific growth factors containing media and extracellular matrix (ECM) or an appropriate substrate for adhesi
Externí odkaz:
https://doaj.org/article/fc5de05542b24598b284a81302eedffd
Publikováno v:
Stem Cells International, Vol 2016 (2016)
The lipophilic statin lovastatin decreases cholesterol synthesis and is a safe and effective treatment for the prevention of cardiovascular diseases. Growing evidence points at antitumor potential of lovastatin. Therefore, understanding the molecular
Externí odkaz:
https://doaj.org/article/37cc1f4f69de465fa8df3fb699395129
Publikováno v:
Stem Cells International, Vol 2014 (2014)
Transcription factors NANOG, OCT4, and SOX2 regulate self-renewal and pluripotency in human embryonic stem (hES) cells; however, their expression profiles during early differentiation of hES cells are unclear. In this study, we used multiparameter fl
Externí odkaz:
https://doaj.org/article/9ab50573cdac458b91086b7a178258d1
Publikováno v:
International Journal of Cell Biology, Vol 2014 (2014)
As cyclin-dependent kinases (CDKs) regulate cell cycle progression and RNA transcription, CDKs are attractive targets for creating cancer cell treatments. In this study we investigated the effects of the small molecular agent NU6140 (inhibits CDK2 an
Externí odkaz:
https://doaj.org/article/0e5362c80e754ff2ab7b495fe0d68bd1
Autor:
Arnold Kristjuhan, Helen Vaher, Annika Trei, Inge Varik, Tõnis Org, Laura Pajusaar, Toivo Maimets, Indrek Teino, Antti Matvere, Martin Pook, Keyt Uudeküll
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9052, p 9052 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9052, p 9052 (2020)
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor, which mediates the effects of a variety of environmental stimuli in multiple tissues. Recent advances in AHR biology have underlined its importance in cells with high develop
Autor:
Martin Pook, Annika Trei, Egle-Helene Ervin, Indrek Teino, Valmar Kasuk, Margus Pooga, Toivo Maimets
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2014 (2014)
Stem Cells International, Vol 2014 (2014)
Transcription factors NANOG, OCT4, and SOX2 regulate self-renewal and pluripotency in human embryonic stem (hES) cells; however, their expression profiles during early differentiation of hES cells are unclear. In this study, we used multiparameter fl
Publikováno v:
International Journal of Cell Biology, Vol 2014 (2014)
International Journal of Cell Biology
International Journal of Cell Biology
As cyclin-dependent kinases (CDKs) regulate cell cycle progression and RNA transcription, CDKs are attractive targets for creating cancer cell treatments. In this study we investigated the effects of the small molecular agent NU6140 (inhibits CDK2 an