Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Annika Timm"'
Autor:
Ingo Ott, Valentina Gandin, Claudia Schmidt, Annika Timm, Viktor Brabec, Uttara Basu, Hana Kostrhunova, Dan Gibson, Tomer Babu
Publikováno v:
Journal of Medicinal Chemistry. 64:11364-11378
"Multi-action" Pt(IV) derivatives of cisplatin with combretastatin A4 (CA4) bioactive ligands that are conjugated to Pt(IV) by carbonate are unique because the ligand (IC50 < 10 nM) is dramatically 1000-folds more cytotoxic than cisplatin in vitro. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a36b6b434ae105733f5a0b2986452a0
https://doi.org/10.1021/acs.jmedchem.1c00706
https://doi.org/10.1021/acs.jmedchem.1c00706
Autor:
Ingo Ott, Stefanie Haeberle, Rodrigo A. Gama-Brambila, Andrea Savarino, Marina Lusic, Uttara Basu, Claudia Schmidt, Shahrouz Ghafoory, Miguel A. Andrade-Navarro, Eva Hadaschik, Annika Timm, Nikolaos Tsopoulidis, Oliver T. Fackler, Stefan Wölfl, Iart Luca Shytaj, Andrea S. Bauer, Katerina Taškova, Jörg D. Hoheisel, Jannick Theobald, Xinlai Cheng, Jessica Wölker
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Gold compounds have a long history of use as immunosuppressants, but their precise mechanism of action is not completely understood. Using our recently developed liver-on-a-chip platform we now show that gold compounds containing planar N-heterocycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d39cf27594a4f9d5195032ccc8521d
https://doi.org/10.1038/s42003-019-0716-8
https://doi.org/10.1038/s42003-019-0716-8