Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Annika Sommer"'
Autor:
Markus Schulze, Annika Sommer, Sonja Plötz, Michaela Farrell, Beate Winner, Janina Grosch, Jürgen Winkler, Markus J. Riemenschneider
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-18 (2018)
Abstract Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson’s disease (PD) have allowed insights into the mechanisms of neurodegeneration. In the larger cohort of patients with sporadic PD, iPSC based inf
Externí odkaz:
https://doaj.org/article/9bc705bbdc794478a15e25e4938f2b62
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Neuronal degeneration is a common mechanism of many neurological diseases including Parkinson’s disease (PD), Alzheimer’s disease (AD), and Multiple Sclerosis (MS). While AD and PD are classical neurodegenerative diseases, the primary pa
Externí odkaz:
https://doaj.org/article/1e639803ced94d399290f585a59bf2af
Autor:
Heiko Zimmermann, Julia Majer, Johanna Kaindl, Ina Meiser, Florian Krach, Jürgen Winkler, Alisa Katsen-Globa, Julia C. Neubauer, Beate Winner, Annika Sommer
Publikováno v:
Stem Cells Translational Medicine
Human induced pluripotent stem cells (hiPSCs) are an important tool for research and regenerative medicine, but their efficient cryopreservation remains a major challenge. The current gold standard is slow-rate freezing of dissociated colonies in sus
Autor:
Martin Regensburger, Mandy Krumbiegel, Steffen Uebe, Sonja Ploetz, Anita Rauch, Udo Trautmann, Arif B. Ekici, Frank Edenhofer, Katharina Günther, Annika Sommer, Beate Winner, Bernt Popp, Cornelia Kraus, Zacharias Kohl, André Reis, Michaela Farrell, Janina Grosch, Jürgen Winkler, Reza Asadollahi
Publikováno v:
Scientific reports
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disease models and for potential therapeutic use. We describe the comprehensive analysis in the ForIPS consortium: an iPSC collection from donors with neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a1174c087161ef3c0f9230fa525275
http://gala.gre.ac.uk/id/eprint/36707/1/36707_ASADOLLAHI_Need_for_high_resolution.pdf
http://gala.gre.ac.uk/id/eprint/36707/1/36707_ASADOLLAHI_Need_for_high_resolution.pdf
Autor:
Steffen Uebe, Cornelia Kraus, Arif B. Ekici, Beate Winner, Katharina Günther, Michaela Farrell, André Reis, Sonja Ploetz, Janina Grosch, Bernt Popp, J. Winkler, Zacharias Kohl, Martin Regensburger, Anita Rauch, Reza Asadollahi, Udo Trautmann, Mandy Krumbiegel, Frank Edenhofer, Annika Sommer
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disease models and for potential therapeutic use. We describe the comprehensive analysis in the ForIPS consortium: an iPSC collection from donors with neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48792d209918b9a905eaf693e7924ee6
https://doi.org/10.1101/379818
https://doi.org/10.1101/379818
Autor:
Jürgen Winkler, Daniela Graef, Fred H. Gage, Franz Marxreiter, Florian Krach, Michele Maroni, Wei Xiang, Iryna Prots, Markus J. Riemenschneider, Gene W. Yeo, Beate Winner, Esther Eberhardt, Annika Sommer, Zacharias Kohl, Janina Grosch, Tanja Fadler
Publikováno v:
Cell stem cell. 23(1)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive degeneration of midbrain neurons (MBNs). Recent evidence suggests contribution of the adaptive immune system in PD. Here, we show a role for human T lymphocytes
Publikováno v:
Biotechnology journal. 10(10)
Reprogramming of patient cells to human induced pluripotent stem cells (hiPSC) has facilitated in vitro disease modeling studies aiming at deciphering the molecular and cellular mechanisms that contribute to disease pathogenesis and progression. To f
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1427-1445 (2019)
Externí odkaz:
https://doaj.org/article/b2df231c5db7440cb7b83b260ac40900
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 3, Pp 866-883 (2015)
Background/Aims: Ursodeoxycholic acid, which in vivo is rapidly converted into its taurine conjugate, is frequently used for the treatment of cholestatic liver disease. Apart from its choleretic effects, tauroursodeoxycholate (TUDC) can protect hepat
Externí odkaz:
https://doaj.org/article/13cb487776b147049f76050d7478b78b
Autor:
Tabea A Mundinger, Annika Sommerfeld, Roland Reinehr, Joachim P Spatz, Dieter Häussinger, Heike Boehm
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48100 (2012)
Hepatocyte volume regulation has been shown to play an important role in cellular metabolism, proliferation, viability and especially in hepatic functions such as bile formation and proteolysis. Recent studies on liver explants led to the assumption
Externí odkaz:
https://doaj.org/article/1fbc59316af744c7b433d0b65656fce0