Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Annika Raschdorf"'
Autor:
Annika Sünderhauf, Maren Hicken, Heidi Schlichting, Kerstin Skibbe, Mohab Ragab, Annika Raschdorf, Misa Hirose, Holger Schäffler, Arne Bokemeyer, Dominik Bettenworth, Anne G. Savitt, Sven Perner, Saleh Ibrahim, Ellinor I. Peerschke, Berhane Ghebrehiwet, Stefanie Derer, Christian Sina
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 229-250 (2021)
Background & Aims: Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC). We hy
Externí odkaz:
https://doaj.org/article/3c9778069d6f49cc96087014960b017d
Autor:
Annika Raschdorf, Annika Sünderhauf, Kerstin Skibbe, Berhane Ghebrehiwet, Ellinor I. Peerschke, Christian Sina, Stefanie Derer
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity. It i
Externí odkaz:
https://doaj.org/article/c0e6039d992e48e782be4ae85be3b831
Autor:
Annika Sünderhauf, Annika Raschdorf, Maren Hicken, Heidi Schlichting, Franziska Fetzer, Ann-Kathrin Brethack, Sven Perner, Claudia Kemper, Berhane Ghebrehiwet, Christian Sina, Stefanie Derer
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Self-sustained cell proliferation constitutes one hallmark of cancer enabled by aerobic glycolysis which is characterized by imbalanced glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) activity, named the Warburg effect. The C1q bindin
Externí odkaz:
https://doaj.org/article/576dd1fe5c224107a13177e1f38d0d39
Autor:
Kerstin Skibbe, Ann-Kathrin Brethack, Annika Sünderhauf, Mohab Ragab, Annika Raschdorf, Maren Hicken, Heidi Schlichting, Joyce Preira, Jennifer Brandt, Darko Castven, Bandik Föh, René Pagel, Jens U. Marquardt, Christian Sina, Stefanie Derer
Publikováno v:
Cancers, Vol 13, Iss 22, p 5817 (2021)
To enable rapid proliferation, colorectal tumor cells up-regulate epidermal growth factor receptor (EGFR) signaling and aerobic glycolysis, resulting in substantial lactate release into the tumor microenvironment and impaired anti-tumor immune respon
Externí odkaz:
https://doaj.org/article/5cd64188174e4c99bfdca3d7276a666f
Autor:
Dominik Bettenworth, Anne G. Savitt, Annika Raschdorf, Berhane Ghebrehiwet, Annika Sünderhauf, Stefanie Derer, Holger Schäffler, Ellinor I.B. Peerschke, Kerstin Skibbe, Misa Hirose, Heidi Schlichting, Maren Hicken, Christian Sina, Saleh M. Ibrahim, Mohab Ragab, Arne Bokemeyer, Sven Perner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 229-250 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 229-250 (2021)
Background & Aims Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC). We hyp
Loss of p32 triggers energy deficiency and impairs goblet cell differentiation in ulcerative colitis
Autor:
Dominik Bettenworth, Arne Bokemeyer, Kerstin Skibbe, Ellinor I.B. Peerschke, Heidi Schlichting, Annika Raschdorf, Mohab Ragab, Misa Hirose, Sven Perner, Anne G. Savitt, Holger Schäffler, Berhane Ghebrehiwet, Maren Hicken, Stefanie Derer, Christian Sina, Saleh M. Ibrahim, Annika Sünderhauf
Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell (GC) dysfunction have been attributed to the pathology of ulcerative colitis (UC). We hypothesized tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc7900c708a48e64b3650b180fe1b7e
https://doi.org/10.1101/2020.12.09.417915
https://doi.org/10.1101/2020.12.09.417915
Autor:
Annika, Raschdorf, Annika, Sünderhauf, Kerstin, Skibbe, Berhane, Ghebrehiwet, Ellinor I, Peerschke, Christian, Sina, Stefanie, Derer
Publikováno v:
Frontiers in Oncology
Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity. It i