Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Annika Pfeiffer"'
Autor:
Christina Wolf, Alireza Pouya, Sara Bitar, Annika Pfeiffer, Diones Bueno, Liliana Rojas-Charry, Sabine Arndt, David Gomez-Zepeda, Stefan Tenzer, Federica Dal Bello, Caterina Vianello, Sandra Ritz, Jonas Schwirz, Kristina Dobrindt, Michael Peitz, Eva-Maria Hanschmann, Pauline Mencke, Ibrahim Boussaad, Marion Silies, Oliver Brüstle, Marta Giacomello, Rejko Krüger, Axel Methner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
GDAP1 mutations effect Charcot-Marie-Tooth disease 4A by inhibiting the pyruvate dehydrogenase complex and restricting mitochondrial localization of dynamin-related protein 1 through alterations of the actin cytoskeleton.
Externí odkaz:
https://doaj.org/article/9641c18a790e4040bf3d22838d1e06f0
Autor:
Geethani Bandara, Guido H. Falduto, Andrea Luker, Yun Bai, Annika Pfeiffer, Justin Lack, Dean D. Metcalfe, Ana Olivera
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The HMC-1.2 human mast cell (huMC) line is often employed in the study of attributes of neoplastic huMCs as found in patients with mastocytosis and their sensitivity to interventional drugs in vitro and in vivo. HMC-1.2 cells express constitutively a
Externí odkaz:
https://doaj.org/article/f228152ee4b24e9aa7a9dcf036833746
Autor:
Denisa Bojkova, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Joshua D. Kandler, Annika Pfeiffer, Julian U.G. Wagner, Mariana Shumliakivska, Stefanie Dimmeler, Ruth Olmer, Ulrich Martin, Florian W.R. Vondran, Tuna Toptan, Florian Rothweiler, Richard Zehner, Holger F. Rabenau, Karen L. Osman, Steven T. Pullan, Miles W. Carroll, Richard Stack, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl, Jr.
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105944- (2023)
Summary: Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for monitoring the replication of SARS-CoV-2 isolates from different v
Externí odkaz:
https://doaj.org/article/4a88cf04c85349bf88133734b02945c5
Autor:
Annika Pfeiffer, Jennifer D. Petersen, Guido H. Falduto, David Eric Anderson, Joshua Zimmerberg, Dean D. Metcalfe, Ana Olivera
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract Activating mutations in the receptor KIT promote the dysregulated proliferation of human mast cells (huMCs). The resulting neoplastic huMCs secrete extracellular vesicles (EVs) that can transfer oncogenic KIT among other cargo into recipient
Externí odkaz:
https://doaj.org/article/165c68a2761947fb95bb85c81dfb9874
Autor:
Guido Hernan Falduto, Annika Pfeiffer, Qunshu Zhang, Yuzhi Yin, Dean Darrel Metcalfe, Ana Olivera
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mast cell hyperactivity and accumulation in tissues are associated with allergy and other mast cell-related disorders. However, the molecular pathways regulating mast cell survival in homeostasis and disease are not completely understood. As glioma-a
Externí odkaz:
https://doaj.org/article/d9c1cd69537c452ca1740f80125ad1e7
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007315 (2018)
Ribonucleotides (rNMPs) are frequently incorporated during replication or repair by DNA polymerases and failure to remove them leads to instability of nuclear DNA (nDNA). Conversely, rNMPs appear to be relatively well-tolerated in mitochondrial DNA (
Externí odkaz:
https://doaj.org/article/ff328a5568ff4d1db9e664e303f9af7c
Autor:
Guido Hernan Falduto, Annika Pfeiffer, Qunshu Zhang, Yuzhi Yin, Dean Darrel Metcalfe, Ana Olivera
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mast cell hyperactivity and accumulation in tissues are associated with allergy and other mast cell-related disorders. However, the molecular pathways regulating mast cell survival in homeostasis and disease are not completely understood. As glioma-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf172e7ccb5c64c66a94ea523ae8851
https://pubmed.ncbi.nlm.nih.gov/35251038
https://pubmed.ncbi.nlm.nih.gov/35251038
Autor:
Annika Pfeiffer, Eva-Maria Hanschmannn, Jonas Schwirz, Sara Bitar, Ibrahim Boussaad, Oliver Brüstle, Kristina Dobrindt, Caterina Vianello, Diones Caeran Bueno, Michael Peitz, Alireza Pouya, Christina Wolf, Stefan Tenzer, Rejko Krüger, Marta Giacomello, Sandra Ritz, Federica Dal Bello, Axel Methner, Sabine Arndt
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d5f3c035b64521c93d8c55a7eb823e
https://doi.org/10.21203/rs.3.rs-209468/v1
https://doi.org/10.21203/rs.3.rs-209468/v1
Autor:
Christina Wolf, Alireza Pouya, Sara Bitar, Annika Pfeiffer, Diones Bueno, Sabine Arndt, Stefan Tenzer, Federica Dal Bello, Caterina Vianello, Sandra Ritz, Jonas Schwirz, Kristina Dobrindt, Michael Peitz, Eva-Maria Hanschmann, Ibrahim Boussaad, Oliver Brüstle, Marta Giacomello, Rejko Krüger, Axel Methner
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c2652e4c4416ccc58c62e557cb4e95
https://doi.org/10.1101/2021.03.04.433895
https://doi.org/10.1101/2021.03.04.433895
Autor:
Laura K. Herzog, Magdalena B. Rother, Ulrike Kühbacher, Martijn S. Luijsterburg, Haico van Attikum, Rashmi G. Shah, Henriette Stoy, Girish M. Shah, Nico P. Dantuma, Annika Pfeiffer
Publikováno v:
Journal of Cell Science, 134(3). COMPANY BIOLOGISTS LTD
DNA damage-induced SUMOylation serves as a signal for two antagonizing proteins that both stimulate repair of DNA double-strand breaks (DSBs). Here, we demonstrate that the SUMO-dependent recruitment of the deubiquitylating enzyme ataxin-3 to DSBs, u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59659e8781fbba2c9bbf54ca8176fa63
https://hdl.handle.net/1887/3213867
https://hdl.handle.net/1887/3213867