Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Annika N, Alexopoulou"'
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 1 and 2. Generation and Characterisation of ECCre+;FAKY397F/Y397F and ECCre+;FAKY861F/Y861F mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5282133926484d2f37715e73d3989246
https://doi.org/10.1158/0008-5472.22422237.v1
https://doi.org/10.1158/0008-5472.22422237.v1
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 6. Knocking down Ang-2 in B16F0s cells ablates angiogenic response in ECCre+;FAKY861F/Y861F mice in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ed9c4100bd25c2f70043fe68231339
https://doi.org/10.1158/0008-5472.22422225.v1
https://doi.org/10.1158/0008-5472.22422225.v1
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 4. Loss of endothelial cell FAK-Y397 or FAK-Y861 phosphorylation has no detectable effect on blood vessel perfusion or maturation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b8458471374ff022d35c585257d1ec
https://doi.org/10.1158/0008-5472.22422231
https://doi.org/10.1158/0008-5472.22422231
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Expression of focal adhesion kinase (FAK) in endothelial cells (EC) is essential for angiogenesis, but how FAK phosphorylation at tyrosine-(Y)397 and Y861 regulate tumor angiogenesis in vivo is unknown. Here, we show that tumor growth and angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eee9a002e76a2569618268b1a0af530
https://doi.org/10.1158/0008-5472.c.6511158.v1
https://doi.org/10.1158/0008-5472.c.6511158.v1
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 3. Levels of tumour hypoxia are enhanced in ECCre+;FAK397F/397F mice and blood vessel density reduced in early stage CMT19T tumours in ECCre+;FAKY861F/Y861F mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257505d4dbf7c16768e926fe05e65283
https://doi.org/10.1158/0008-5472.22422234
https://doi.org/10.1158/0008-5472.22422234
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 7. Loss of endothelial cell FAK-Y397 or FAK-Y861-phosphorylation does not affect total levels of β1 Integrin, but affects clustering at focal contact sites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8d3777bbcd7178823c9b386a6b6e0f
https://doi.org/10.1158/0008-5472.22422222
https://doi.org/10.1158/0008-5472.22422222
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 5. PlGF and bFGF-induced angiogenesis in vivo is significantly reduced in ECCre+;FAKY397F/Y397F but not ECCre+;FAKY861F/Y861F mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9fccc73757eae95642a8724d1e77a2
https://doi.org/10.1158/0008-5472.22422228.v1
https://doi.org/10.1158/0008-5472.22422228.v1
Autor:
Natalia Bodrug, Ana Rita Pedrosa, Isabelle Fernandez, Kairbaan Hodivala-Dilke, Annika N. Alexopoulou, Maddy Parsons, Bernardo Tavora, Thomas Iskratsch, Edward P. Carter, Vassiliki Kostourou, Silvia Batista, Paraskivi Natalia Georgiou, Delphine M. Lees, Louise E. Reynolds, Jesus Gomez-Escudero, Bryan Serrels
Publikováno v:
Cancer Research. 79:4371-4386
Expression of focal adhesion kinase (FAK) in endothelial cells (EC) is essential for angiogenesis, but how FAK phosphorylation at tyrosine-(Y)397 and Y861 regulate tumor angiogenesis in vivo is unknown. Here, we show that tumor growth and angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d87d678f62910e07ccb9b5d9e53806
https://doi.org/10.1158/0008-5472.can-18-3934
https://doi.org/10.1158/0008-5472.can-18-3934
Autor:
Demetra S.M. Chatzileontiadou, Martina Samiotaki, Melina Stamatiadi, Marina Cotsiki, Nikolaos A.A. Balatsos, Maria Kontou, Demetres D. Leonidas, Annika N. Alexopoulou, George Panayotou
Publikováno v:
Journal of proteome research. 16(10)
Human Angiogenin (hAng) is a member of the ribonuclease A superfamily and a potent inducer of neovascularization. Protein interactions of hAng in the nucleus and cytoplasm of the human umbilical vein cell line EA.hy926 have been investigated by mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d75ad0f100a60f73cd95dfe2f22eec6
https://pubmed.ncbi.nlm.nih.gov/28777577
https://pubmed.ncbi.nlm.nih.gov/28777577
Autor:
Delphine M. Lees, Bernardo Tavora, Isabelle Fernandez, Silvia Batista, Stephen D. Robinson, Kairbaan Hodivala-Dilke, Bryan Serrels, Vassiliki Kostourou, Annika N. Alexopoulou
Publikováno v:
genesis. 52:907-915
Summary Focal adhesion kinase is a non-receptor protein tyrosine kinase with signaling functions downstream of integrins and growth factor receptors. In addition to its role in adhesion, migration, and proliferation it also has non-kinase scaffolding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6835c8f9d6d27665c8127d0da542e73
https://doi.org/10.1002/dvg.22823
https://doi.org/10.1002/dvg.22823