The Guanine-Nucleotide Exchange Factor Caldag Gefi Fine-Tunes Functional Properties of Regulatory T Cells

Autor: Jill R. Crittenden, Christian Freund, Jana Niemz, Ann M. Graybiel, Marina C. Pils, Lothar Jänsch, Melanie Galla, Jochen Huehn, Annika Manns, Eliot Morrison, Stefanie Kliche

Publikováno v: European Journal of Microbiology & Immunology
European Journal of Microbiology & Immunology, Vol 7, Iss 2, Pp 112-126 (2017)
European Journal of Microbiology and Immunology

Using quantitative phosphopeptide sequencing of unstimulated versus stimulated primary murine Foxp3(+) regulatory and Foxp3(-) conventional T cells (Tregs and Tconv, respectively), we detected a novel and differentially regulated tyrosine phosphoryla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c0fa0e859499db3ee5cb5f4acd73f7
https://pubmed.ncbi.nlm.nih.gov/28690878

The FKBP-type domain of the human aryl hydrocarbon receptor-interacting protein reveals an unusual Hsp90 interaction

Autor: Gunter Fischer, Anne-Katrin Paschke, Miriam Linnert, Annika Manns, Christian Lücke, Katja Haupt, Yi-Jan Lin, Matthias Weiwad

Publikováno v: Biochemistry. 52(12)

The aryl hydrocarbon receptor-interacting protein (AIP) has been predicted to consist of an N-terminal FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) domain and a C-terminal tetratricopeptide repeat (TPR) domain, as typically found in FK506-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847edf43ce74a8dd99796cabf51eb840
https://pubmed.ncbi.nlm.nih.gov/23418784