Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Annika Lehmann"'
Autor:
Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Liliana H. Mochmann, Emma Payá Capilla, Rebecca Fritz, Carsten Dittmayer, Corinna Friedrich, Anne Thieme, Philipp Keyl, Armin Jarosch, Simon Schallenberg, Hendrik Bläker, Inga Hoffmann, Claudia Vollbrecht, Annika Lehmann, Michael Hummel, Daniel Heim, Mohamed Haji, Patrick Harter, Benjamin Englert, Stephan Frank, Jürgen Hench, Werner Paulus, Martin Hasselblatt, Wolfgang Hartmann, Hildegard Dohmen, Ursula Keber, Paul Jank, Carsten Denkert, Christine Stadelmann, Felix Bremmer, Annika Richter, Annika Wefers, Julika Ribbat-Idel, Sven Perner, Christian Idel, Lorenzo Chiariotti, Rosa Della Monica, Alfredo Marinelli, Ulrich Schüller, Michael Bockmayr, Jacklyn Liu, Valerie J. Lund, Martin Forster, Matt Lechner, Sara L. Lorenzo-Guerra, Mario Hermsen, Pascal D. Johann, Abbas Agaimy, Philipp Seegerer, Arend Koch, Frank Heppner, Stefan M. Pfister, David T. W. Jones, Martin Sill, Andreas von Deimling, Matija Snuderl, Klaus-Robert Müller, Erna Forgó, Brooke E. Howitt, Philipp Mertins, Frederick Klauschen, David Capper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Sinonasal tumour diagnosis can be complicated by the heterogeneity of disease and classification systems. Here, the authors use machine learning to classify sinonasal undifferentiated carcinomas into 4 molecular classe with differences in differentia
Externí odkaz:
https://doaj.org/article/6b6e398cca1d45b0ab123d7e7294892a
Autor:
Jana Ihlow, Edward Michaelis, Selina Greuel, Verena Heynol, Annika Lehmann, Helena Radbruch, Jenny Meinhardt, Florian Miller, Hermann Herbst, Victor Max Corman, Jörg Westermann, Lars Bullinger, David Horst, Ann-Christin von Brünneck, Sefer Elezkurtaj
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss , Pp 628-635 (2021)
Objectives: In coronavirus disease 2019 (COVID-19), the adaptive immune response is of considerable importance, and detailed cellular immune reactions in the hematological system of patients with severe acute respiratory syndrome coronavirus 2 (SARS-
Externí odkaz:
https://doaj.org/article/30ec50fe0c0e452885856e3244668cf3
Autor:
Claudia Vollbrecht, Dido Lenze, Michael Hummel, Annika Lehmann, Markus Moebs, Nikolaj Frost, Philipp Jurmeister, Leonille Schweizer, Udo Kellner, Manfred Dietel, Maximilian von Laffert
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Rearrangements of the anaplastic lymphoma kinase (ALK) belong to the promising targets in the therapy of advanced non-small cell lung cancer (NSCLC) and are predominantly detected by immunohistochemistry (IHC) and/or fluorescence
Externí odkaz:
https://doaj.org/article/af72e0ed2bf34fe08603e87cd561159e
Autor:
Berit Maria Müller, Elke Keil, Annika Lehmann, Klaus-Jürgen Winzer, Christiane Richter-Ehrenstein, Judith Prinzler, Nikola Bangemann, Angela Reles, Sylvia Stadie, Winfried Schoenegg, Jan Eucker, Marcus Schmidt, Frank Lippek, Korinna Jöhrens, Stefan Pahl, Bruno Valentin Sinn, Jan Budczies, Manfred Dietel, Carsten Denkert
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68252 (2013)
The validated EndoPredict assay is a novel tool to predict the risk of metastases of patients with estrogen receptor positive, HER2 negative breast cancer treated with endocrine therapy alone. It has been designed to integrate genomic and clinical in
Externí odkaz:
https://doaj.org/article/ae95c19dc59548368152647d4ca103a0
Autor:
Claudia Vollbrecht, Inga Hoffmann, Annika Lehmann, Sabine Merkelbach-Bruse, Jana Fassunke, Svenja Wagener-Ryczek, Markus Ball, Lora Dimitrova, Arndt Hartmann, Robert Stöhr, Ramona Erber, Wilko Weichert, Nicole Pfarr, Lisa Bohlmann, Andreas Jung, Wolfgang Dietmaier, Manfred Dietel, David Horst, Michael Hummel
Publikováno v:
Virchows Archiv. 482:697-706
Precision oncology based on specific molecular alterations requires precise and reliable detection of therapeutic targets in order to initiate the optimal treatment. In many European countries—including Germany—assays employed for this purpose ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a855143283d4575525aced9df5df0d
https://doi.org/10.1007/s00428-022-03445-x
https://doi.org/10.1007/s00428-022-03445-x
Autor:
Ralf Kronenwett, Paul Jank, David Horst, Carsten Denkert, Judith Lea Lindner, J. U. Blohmer, Berit M. Pfitzner, Wolfgang D. Schmitt, Annika Lehmann
Publikováno v:
Breast Cancer Research and Treatment
Background Risk assessment on the molecular level is important in predictive pathology to determine the risk of metastatic disease for ERpos, HER2neg breast cancer. The gene expression test EndoPredict (EP) was trained and validated for prediction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb6587a58ffbfb389e0714ce136191
https://doi.org/10.1007/s10549-021-06415-0
https://doi.org/10.1007/s10549-021-06415-0
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
Autor:
Christine Sers, Alexandra Trinks, Frederick Klauschen, David Horst, Annika Lehmann, Nils Blüthgen, Philipp Jurmeister, Markus Morkel, Jennifer Wiederspahn, Benedikt Obermayer, Jens Neudecker, Xizi Liang, Christine S. Falk, Jan Patrick Pett, Florian Uhlitz, Jens-Carsten Rückert, Aron Elsner, Philip Bischoff, Tomasz Dziodzio, Dieter Beule
Publikováno v:
Oncogene
Recent developments in immuno-oncology demonstrate that not only cancer cells, but also the tumor microenvironment can guide precision medicine. A comprehensive and in-depth characterization of the tumor microenvironment is challenging since its cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe55482497558cb207949eeea1a5bab
https://doi.org/10.1038/s41388-021-02054-3
https://doi.org/10.1038/s41388-021-02054-3
Autor:
Martina Kirchner, Peter Schirmacher, Michael Hummel, Volker Endris, Matthias Evert, Carolin Ploeger, Ulrich Lehmann, Marcel Trautmann, Julia Glade, Andreas Jung, Nicole Pfarr, Sabine Merkelbach-Bruse, Eva Wardelmann, Albrecht Stenzinger, Annika Lehmann, Wilko Weichert, Reinhard Büttner, Manfred Dietel, Jörg Kumbrink, Thomas Kirchner, Hans Kreipe, Daniel Kazdal, Wolfgang Dietmaier, David Horst
Publikováno v:
Genes, Chromosomes and Cancer. 59:445-453
Gene fusions involving the three neurotrophic tyrosine receptor kinase genes NTRK1, NTRK2, or NTRK3 were identified as oncogenic drivers in many cancer types. Two small molecule inhibitors have been tested in clinical trials recently and require the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbc8ccd2e4ac88ef0ec9de70dee807d
https://doi.org/10.1002/gcc.22853
https://doi.org/10.1002/gcc.22853
Autor:
CHRISTIAN DOLL, CLAUDIUS STEFFEN, BENEDICTA BECK-BROICHSITTER, MAXIMILIAN RICHTER, KONRAD NEUMANN, ANNE POHRT, PHILIPP LOHNEIS, ANNIKA LEHMANN, MAX HEILAND, CARMEN STROMBERGER, ANNEKATRIN COORDES, KORINNA JOHRENS, JAN-DIRK RAGUSE
Publikováno v:
Anticancer research. 42(5)
This study analyzed the expression of p16 in a large cohort of patients suffering from oral squamous cell carcinoma (OSCC) who received initial surgical therapy in order to evaluate the prognostic significance of p16 expression and to analyze its val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48aae8cf60c3ad48bbc5ec6fdc0437a5
https://pubmed.ncbi.nlm.nih.gov/35489745
https://pubmed.ncbi.nlm.nih.gov/35489745
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a38af078426eb9827bbce26dc8d7317
https://doi.org/10.2139/ssrn.4074690
https://doi.org/10.2139/ssrn.4074690