Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annika H. Runegaard"'
Autor:
David P.D. Woldbye, Amaia de Diego Ajenjo, Søren H. Christiansen, Annika H. Runegaard, Anders Petersen, Ulrik Gether, Søren H. Jørgensen, Ciarán M. Fitzpatrick, Andreas T. Sørensen, Jesper T. Andreasen, Julia C. McGirr, Nikolaj W. Hansen, Jean-François Perrier
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 90:264-276
Attention-deficit/hyperactivity disorder (ADHD) is a psychiatric disorder characterized by inattention, aberrant impulsivity, and hyperactivity. Although the underlying pathophysiology of ADHD remains unclear, dopamine and norepinephrine signaling or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8d5de9f449a0be076b6dc001930aeb
https://doi.org/10.1016/j.pnpbp.2018.12.004
https://doi.org/10.1016/j.pnpbp.2018.12.004
Autor:
David P.D. Woldbye, Ciarán M. Fitzpatrick, Andreas T. Sørensen, Annika H. Runegaard, Jesper T. Andreasen, Ulrik Gether
Publikováno v:
Pharmacological Reviews. 71:123-156
For more than 60 years, dopamine (DA) has been known as a critical modulatory neurotransmitter regulating locomotion, reward-based motivation, and endocrine functions. Disturbances in DA signaling have been linked to an array of different neurologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a9a922233629e5b8c60b5e9f153b05
https://doi.org/10.1124/pr.117.013995
https://doi.org/10.1124/pr.117.013995
Publikováno v:
European Journal of Neuroscience. 50:2156-2163
In rodents, only a single dose of cocaine or amphetamine is required to cause a marked increase in extracellular dopamine, induce hyperlocomotion and cause persistent plasticity changes within dopaminergic neurons of the ventral tegmental area (VTA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2434fc8b5e83a4d8a2f97a3586d629b
https://doi.org/10.1111/ejn.14082
https://doi.org/10.1111/ejn.14082
Publikováno v:
Gene Therapy. 23:760-766
Epilepsy is a neurological disorder with a prevalence of ≈1% of general population. Available antiepileptic drugs (AEDs) have multiple side effects and are ineffective in 30% of patients. Therefore, development of effective treatment strategies is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a3941d11d962ca76a2a6d641b72590
https://doi.org/10.1038/gt.2016.56
https://doi.org/10.1038/gt.2016.56
Publikováno v:
Neuropharmacology. 161:107663
Amphetamine (AMPH) acts as a substrate of the dopamine transporter (DAT) and causes a dramatic increase in extracellular dopamine (DA). Upon entering DA neurons, AMPH promotes DA efflux via DAT through a mechanism implicating depletion of DA from ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d0748154ddb70efd5c9062dcd6b64b
https://doi.org/10.1016/j.neuropharm.2019.06.002
https://doi.org/10.1016/j.neuropharm.2019.06.002
Publikováno v:
Journal of Visualized Experiments.
Dopamine (DA) is a modulatory neurotransmitter controlling motor activity, reward processes and cognitive function. Impairment of dopaminergic (DAergic) neurotransmission is strongly associated with several central nervous system-associated diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b315acd0427e477c179ac28afa74bea
https://doi.org/10.3791/56093
https://doi.org/10.3791/56093
Publikováno v:
Journal of neuroscience methods. 289
Background The potential of abused drugs to induce addiction and compulsive drug-related behavior is associated with their ability to alter dopamine signaling. Dopamine plays a key role in reward signaling and it has been of great interest to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4b7b9871ef3fa9967b3f214f1df4ef
https://pubmed.ncbi.nlm.nih.gov/28711378
https://pubmed.ncbi.nlm.nih.gov/28711378
Autor:
Ciarán M. Fitzpatrick, Mattias Rickhag, Ulrik Gether, Pia Weikop, Annika H. Runegaard, Kathrine L. Jensen, Ditte Dencker
Cre-driver mouse lines have been extensively used as genetic tools to target and manipulate genetically defined neuronal populations by expression of Cre recombinase under selected gene promoters. This approach has greatly advanced neuroscience but i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eca5a4221b31ab63a3a44ec31e81082
https://europepmc.org/articles/PMC5294347/
https://europepmc.org/articles/PMC5294347/
Autor:
Gitta Wörtwein, Anders Fink-Jensen, Kenneth L. Madsen, Gunnar Sørensen, William A. Owens, Annika H. Runegaard, Lynette C. Daws, Michael Brett Lever, Mattias Rickhag, Pia Weikop, Troels Rahbek-Clemmensen, Kathrine L. Jensen, Nikolaj R. Christensen, Ditte Dencker, Ulrik Gether
Publikováno v:
Jensen, K L, Sørensen, G, Dencker, D, Owens, W A, Rahbek-Clemmensen, T, Brett Lever, M, Runegaard, A H, Riis Christensen, N, Weikop, P, Wörtwein, G, Fink-Jensen, A, Madsen, K L, Daws, L, Gether, U & Rickhag, M 2018, ' PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis ', eNeuro, vol. 5, no. 3 . https://doi.org/10.1523/ENEURO.0422-17.2018
Protein interacting with C-kinase 1 (PICK1) is a widely expressed scaffold protein known to interact via its PSD-95/discs-large/ZO-1 (PDZ)-domain with several membrane proteins including the dopamine (DA) transporter (DAT), the primary target for coc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98271dc35fcf9229351acd751da921f3
https://doi.org/10.1523/eneuro.0422-17.2018
https://doi.org/10.1523/eneuro.0422-17.2018